ES448787A1 - Chemical compounds process for preparing said compounds and process for preparing 6-(p-hydroxyphenyl-glycylamido)-penam or 7-(p-hydroxyphenyl-glycylamido)-cephem compounds - Google Patents
Chemical compounds process for preparing said compounds and process for preparing 6-(p-hydroxyphenyl-glycylamido)-penam or 7-(p-hydroxyphenyl-glycylamido)-cephem compoundsInfo
- Publication number
- ES448787A1 ES448787A1 ES448787A ES448787A ES448787A1 ES 448787 A1 ES448787 A1 ES 448787A1 ES 448787 A ES448787 A ES 448787A ES 448787 A ES448787 A ES 448787A ES 448787 A1 ES448787 A1 ES 448787A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- preparing
- glycylamido
- hydroxyphenyl
- penam
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 4
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- AOJFQRQNPXYVLM-UHFFFAOYSA-N pyridin-1-ium;chloride Chemical compound [Cl-].C1=CC=[NH+]C=C1 AOJFQRQNPXYVLM-UHFFFAOYSA-N 0.000 abstract 2
- RHEFYFUGIMENJN-GLGOKHISSA-N (2,5-dioxopyrrolidin-3-yl) (2R)-2-amino-2-(4-trimethylsilyloxyphenyl)acetate Chemical compound C[Si](OC1=CC=C([C@@H](N)C(=O)OC2C(=O)NC(C2)=O)C=C1)(C)C RHEFYFUGIMENJN-GLGOKHISSA-N 0.000 abstract 1
- XVMSFILGAMDHEY-UHFFFAOYSA-N 6-(4-aminophenyl)sulfonylpyridin-3-amine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=N1 XVMSFILGAMDHEY-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Process for preparing p-trimethylsilyloxy-d - (-) - phenylglycyloxysuccinimide or -phthalimide. The process of the invention comprises reacting d - (-) - p-trimethylsilyloxyphenylglycyl-N-carboxyanhydride with an N-hydroxyimide of the general formula: ** (formula) ** wherein y is defined as above, in the presence of a hydrochloride of a weak amine and in an inert solvent. The reaction is preferably carried out in the presence of pyridine hydrochloride and in methylene chloride. The new compounds thus prepared can be isolated or used in situ in a process for the production of 6- (p-hydroxyphenylglycylamido) -penam or 7- (p-hydroxyphenylglycylamido) -cefem compounds as active esters. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB25447/75A GB1546077A (en) | 1975-06-13 | 1975-06-13 | Chemical compounds process for preparing said compounds and process for preparing 6-(p-hydroxyphenyl-glycylamido)-penam or 7-(p-hydroxyphenyl-glycylamido)-cephem compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES448787A1 true ES448787A1 (en) | 1978-01-01 |
Family
ID=10227825
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES448787A Expired ES448787A1 (en) | 1975-06-13 | 1976-06-11 | Chemical compounds process for preparing said compounds and process for preparing 6-(p-hydroxyphenyl-glycylamido)-penam or 7-(p-hydroxyphenyl-glycylamido)-cephem compounds |
| ES461244A Expired ES461244A1 (en) | 1975-06-13 | 1977-08-01 | Chemical compounds process for preparing said compounds and process for preparing 6-(p-hydroxyphenyl-glycylamido)-penam or 7-(p-hydroxyphenyl-glycylamido)-cephem compounds |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES461244A Expired ES461244A1 (en) | 1975-06-13 | 1977-08-01 | Chemical compounds process for preparing said compounds and process for preparing 6-(p-hydroxyphenyl-glycylamido)-penam or 7-(p-hydroxyphenyl-glycylamido)-cephem compounds |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS52260A (en) |
| BR (1) | BR7603793A (en) |
| CA (1) | CA1071189A (en) |
| DE (1) | DE2626280A1 (en) |
| DK (1) | DK263976A (en) |
| ES (2) | ES448787A1 (en) |
| FI (1) | FI761627A (en) |
| GB (1) | GB1546077A (en) |
| NL (1) | NL7606360A (en) |
| PT (1) | PT65212B (en) |
| SE (1) | SE7606567L (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0379892A (en) * | 1989-08-21 | 1991-04-04 | Yoshihisa Miura | Ferrule with chuck |
| DE102008063055A1 (en) | 2008-12-23 | 2010-08-05 | Uhde Gmbh | Process for using the gas from a gasifier synthesis gas |
-
1975
- 1975-06-13 GB GB25447/75A patent/GB1546077A/en not_active Expired
-
1976
- 1976-06-08 FI FI761627A patent/FI761627A/fi not_active Application Discontinuation
- 1976-06-09 CA CA254,379A patent/CA1071189A/en not_active Expired
- 1976-06-10 SE SE7606567A patent/SE7606567L/en unknown
- 1976-06-11 PT PT65212A patent/PT65212B/en unknown
- 1976-06-11 DK DK263976A patent/DK263976A/en not_active Application Discontinuation
- 1976-06-11 BR BR7603793A patent/BR7603793A/en unknown
- 1976-06-11 DE DE19762626280 patent/DE2626280A1/en not_active Withdrawn
- 1976-06-11 ES ES448787A patent/ES448787A1/en not_active Expired
- 1976-06-11 NL NL7606360A patent/NL7606360A/en not_active Application Discontinuation
- 1976-06-14 JP JP51069639A patent/JPS52260A/en active Pending
-
1977
- 1977-08-01 ES ES461244A patent/ES461244A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2626280A1 (en) | 1976-12-30 |
| PT65212B (en) | 1977-11-23 |
| FI761627A (en) | 1976-12-14 |
| BR7603793A (en) | 1977-02-08 |
| NL7606360A (en) | 1976-12-15 |
| SE7606567L (en) | 1976-12-14 |
| PT65212A (en) | 1976-07-01 |
| JPS52260A (en) | 1977-01-05 |
| GB1546077A (en) | 1979-05-16 |
| DK263976A (en) | 1976-12-14 |
| ES461244A1 (en) | 1978-05-01 |
| CA1071189A (en) | 1980-02-05 |
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