ES460678A1 - Un procedimiento para la preparacion de nuevos derivados delcromano. - Google Patents

Un procedimiento para la preparacion de nuevos derivados delcromano.

Info

Publication number
ES460678A1
ES460678A1 ES460678A ES460678A ES460678A1 ES 460678 A1 ES460678 A1 ES 460678A1 ES 460678 A ES460678 A ES 460678A ES 460678 A ES460678 A ES 460678A ES 460678 A1 ES460678 A1 ES 460678A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
hydrogen
chromenes
chromane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES460678A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES460678A1 publication Critical patent/ES460678A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Abstract

Un procedimiento para la preparación de nuevos derivados del cromano de fórmula (I), o una sal del mismo, donde R1 es un átomo de hidrógeno o un grupo alquilo C1-4 o benciclo; R2 es un átomo de hidrógeno o un grupo alquilo C1-4 o está unido a R1 de manera que el radical NR1R2 es un grupo heterociclico saturado de 5,6 o 7 miembros; R3 es hidrógeno o un grupo alquilo C1-4 o acilo C1-4; R4 es un grupo aromático;
ES460678A 1975-06-03 1977-07-12 Un procedimiento para la preparacion de nuevos derivados delcromano. Expired ES460678A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB24005/75A GB1493998A (en) 1975-06-03 1975-06-03 Propanolamine derivatives

Publications (1)

Publication Number Publication Date
ES460678A1 true ES460678A1 (es) 1978-05-16

Family

ID=10204870

Family Applications (2)

Application Number Title Priority Date Filing Date
ES448484A Expired ES448484A1 (es) 1975-06-03 1976-06-02 Un procedimiento para la preparacion de nuevos derivados de cromado.
ES460678A Expired ES460678A1 (es) 1975-06-03 1977-07-12 Un procedimiento para la preparacion de nuevos derivados delcromano.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES448484A Expired ES448484A1 (es) 1975-06-03 1976-06-02 Un procedimiento para la preparacion de nuevos derivados de cromado.

Country Status (20)

Country Link
US (2) US4093631A (es)
JP (1) JPS51146449A (es)
AT (1) AT347944B (es)
AU (1) AU497811B2 (es)
BE (1) BE842352A (es)
CA (1) CA1095517A (es)
CH (1) CH622241A5 (es)
DE (1) DE2624570A1 (es)
DK (1) DK243176A (es)
ES (2) ES448484A1 (es)
FR (2) FR2313034A1 (es)
GB (1) GB1493998A (es)
HK (1) HK5381A (es)
HU (1) HU174100B (es)
IE (1) IE43312B1 (es)
IL (1) IL49655A (es)
KE (1) KE3112A (es)
NL (1) NL7605922A (es)
SE (1) SE422795B (es)
ZA (1) ZA763267B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2857224A (en) * 1956-10-05 1958-10-21 Re Domenic Del Self waiting table serving apparatus
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
EP0020018B1 (en) * 1979-05-19 1983-06-01 Beecham Group Plc Chroman derivatives, processes for their preparation and pharmaceutical compositions containing them
US4255426A (en) * 1979-07-09 1981-03-10 Pfizer Inc. 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines
US4316899A (en) * 1979-08-24 1982-02-23 Beecham Group Limited Chromanone derivatives, a process for their preparation and compositions containing them
US4394382A (en) * 1980-06-17 1983-07-19 Kowa Company, Ltd. Dihydrobenzopyran compounds and pharmaceutical composition comprising said compounds
HU184359B (en) * 1980-12-16 1984-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing substituted acyl-carbamides
JPS5832847A (ja) * 1981-08-20 1983-02-25 Mitsubishi Chem Ind Ltd （３−アミノプロポキシ）ビベンジル類
US4513135A (en) * 1982-03-05 1985-04-23 Eli Lilly And Company Diaryl-pyrazine derivatives affecting GABA binding
EP0107615B1 (de) * 1982-09-30 1992-10-28 Ciba-Geigy Ag Mit Bis- oder Tris-(polyalkylpiperidinyl-amino)-1,3,5-triazine stabilisierte Polyolefine
AU548450B2 (en) * 1983-08-08 1985-12-12 G.D. Searle & Co. Substituted dihydrobenzopyrans
JPS60202872A (ja) * 1984-03-27 1985-10-14 Kaken Pharmaceut Co Ltd ベンゾフラン誘導体、その製法およびそれを有効成分とする降圧剤
US4758678A (en) * 1986-07-18 1988-07-19 Pennwalt Corporation Preparation of 7-(2,3-epoxypropoxy)flavone
US5093353A (en) * 1988-05-20 1992-03-03 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US4950684A (en) * 1988-05-20 1990-08-21 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US5219883A (en) * 1988-05-20 1993-06-15 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US6372776B2 (en) * 1997-06-12 2002-04-16 Novo Nordisk A/S Crystalline(−)-3R,4R-trans-7-methoxy-2,2-dimethyl-3-phenyl-4-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}chromane, hydrogen maleate
JP2007008822A (ja) * 2005-06-28 2007-01-18 Tokuyama Corp ジヒドロベンゾピラン誘導体の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518002C3 (de) * 1965-01-02 1975-01-23 Merck Patent Gmbh, 6100 Darmstadt Isoflavane und Isoflavene und Verfahren zu Ihrer Herstellung sowie diese enthaltende Arzneimittel
US3506654A (en) * 1966-09-15 1970-04-14 Syntex Corp Benzylidene derivatives of chromene,thiochromene,quinoline,and n-alkyl quinoline and corresponding benzyl tertiary carbinol intermediates
DE2162721A1 (de) * 1970-12-19 1972-06-22 Dr L Zambeletti SpA, Mailand (Italien) Substituierte Cumarine und Verfahren zu ihrer Herstellung
US4146539A (en) * 1974-07-30 1979-03-27 Beecham Group Limited Anorexic chromans
GB1497161A (en) * 1975-07-19 1978-01-05 Beecham Group Ltd Naphthyl derivatives

Also Published As

Publication number Publication date
BE842352A (fr) 1976-11-29
IL49655A (en) 1979-10-31
FR2361868A1 (fr) 1978-03-17
US4093631A (en) 1978-06-06
NL7605922A (nl) 1976-12-07
IE43312B1 (en) 1981-01-28
CH622241A5 (es) 1981-03-31
FR2361868B1 (es) 1980-03-21
GB1493998A (en) 1977-12-07
IE43312L (en) 1976-12-03
AU1461576A (en) 1977-12-08
DK243176A (da) 1976-12-04
ES448484A1 (es) 1977-12-01
ZA763267B (en) 1977-05-25
HU174100B (es) 1979-11-28
KE3112A (en) 1981-02-20
AU497811B2 (en) 1979-01-11
FR2313034B1 (es) 1979-03-30
HK5381A (en) 1981-02-27
IL49655A0 (en) 1976-09-30
SE422795B (sv) 1982-03-29
CA1095517A (en) 1981-02-10
SE7605825L (sv) 1976-12-04
US4234726A (en) 1980-11-18
DE2624570A1 (de) 1976-12-23
JPS51146449A (en) 1976-12-16
ATA403076A (de) 1978-06-15
AT347944B (de) 1979-01-25
FR2313034A1 (fr) 1976-12-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202