ES459838A1 - Un procedimiento para preparar cloruro de sulfinilo. - Google Patents

Un procedimiento para preparar cloruro de sulfinilo.

Info

Publication number
ES459838A1
ES459838A1 ES459838A ES459838A ES459838A1 ES 459838 A1 ES459838 A1 ES 459838A1 ES 459838 A ES459838 A ES 459838A ES 459838 A ES459838 A ES 459838A ES 459838 A1 ES459838 A1 ES 459838A1
Authority
ES
Spain
Prior art keywords
preparing
exomethylenecepham sulfoxide
sulfoxide
penicillin sulfoxides
exomethylenecepham
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES459838A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES459838A1 publication Critical patent/ES459838A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Un procedimiento para preparar cloruro de sulfinilo de fórmula (Ver fórmula 1), haciendo reaccionar un sulfóxido de penicilina de fórmula (Ver fórmula 2), con un agente de halogenación de N-cloro a una temperatura de aproximadamente 75ºC a aproximadamente 135ºC en un solvente inerte, bajo condiciones anhidras y en presencia de un compuesto epóxido.
ES459838A 1976-06-16 1977-06-16 Un procedimiento para preparar cloruro de sulfinilo. Expired ES459838A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/696,674 US4075203A (en) 1976-06-16 1976-06-16 Process for preparing a 3-exomethylenecepham sulfoxide from penicillin sulfoxides

Publications (1)

Publication Number Publication Date
ES459838A1 true ES459838A1 (es) 1978-04-01

Family

ID=24798089

Family Applications (1)

Application Number Title Priority Date Filing Date
ES459838A Expired ES459838A1 (es) 1976-06-16 1977-06-16 Un procedimiento para preparar cloruro de sulfinilo.

Country Status (27)

Country Link
US (1) US4075203A (es)
JP (1) JPS6043339B2 (es)
AR (1) AR219926A1 (es)
AT (1) AT352138B (es)
AU (1) AU508748B2 (es)
BE (1) BE855694A (es)
CA (1) CA1083579A (es)
CH (1) CH627161A5 (es)
CS (1) CS198246B2 (es)
DD (1) DD131018A5 (es)
DE (1) DE2726394A1 (es)
DK (1) DK264577A (es)
ES (1) ES459838A1 (es)
FR (1) FR2355005A1 (es)
GB (1) GB1584105A (es)
HU (1) HU179966B (es)
IE (1) IE45195B1 (es)
IL (1) IL52117A (es)
NL (1) NL189609C (es)
NZ (1) NZ184136A (es)
PH (1) PH13001A (es)
PL (1) PL103103B1 (es)
PT (1) PT66642B (es)
RO (1) RO71066A (es)
SE (1) SE438329B (es)
YU (1) YU143177A (es)
ZA (1) ZA772907B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138553A (en) * 1976-11-11 1979-02-06 Teijin Limited 3-Methylene cephalosporanic acid derivatives and process for preparation thereof
US4159272A (en) * 1977-09-01 1979-06-26 Eli Lilly And Company Process for 2-chlorosulfinylazetidin-4-ones
US4289695A (en) * 1978-11-13 1981-09-15 Eli Lilly And Company Process for preparing 2-chlorosulfinylazetidinones
US5126446A (en) * 1991-01-04 1992-06-30 Eli Lilly And Company Process for 3-exomethylenecepham sulfoxide esters
US5350845A (en) * 1992-04-08 1994-09-27 Eli Lilly And Company Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters
US5347000A (en) * 1992-11-05 1994-09-13 Ranbaxy Laboratories Ltd. Process for the preparation of 2-chlorosulfinylazetidinone
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
US6116362A (en) * 1998-07-09 2000-09-12 Case Corporation Articulated vehicle

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS551272B2 (es) * 1972-04-14 1980-01-12
US3843682A (en) * 1972-05-15 1974-10-22 Lilly Co Eli 2-chlorosulfinyl-3-imido-azetedin-4-ones
GB1442785A (en) * 1972-12-09 1976-07-14 Nikken Chemicals Co Ltd Desacetoxy ceaphalosporanic acids
NL7411505A (nl) * 1973-09-06 1975-03-10 Rhone Poulenc Sa Werkwijze voor de bereiding en toepassing van nieuwe 7-trichlooraceetamido-3-desacetoxy-cefa- losporanzuurpreparaten.
CA1069126A (en) * 1974-12-24 1980-01-01 Eli Lilly And Company Sulfinyl halides and their preparation from penicillin sulfoxides

Also Published As

Publication number Publication date
CS198246B2 (en) 1980-05-30
AT352138B (de) 1979-09-10
US4075203A (en) 1978-02-21
ZA772907B (en) 1978-12-27
IE45195B1 (en) 1982-07-14
AU508748B2 (en) 1980-04-03
YU143177A (en) 1982-10-31
RO71066A (ro) 1982-10-26
PT66642B (en) 1978-11-09
CA1083579A (en) 1980-08-12
DD131018A5 (de) 1978-05-24
DE2726394C2 (es) 1990-03-15
PT66642A (en) 1977-07-01
DK264577A (da) 1977-12-17
BE855694A (fr) 1977-12-15
PL198878A1 (pl) 1978-04-10
AU2542777A (en) 1978-11-30
JPS537668A (en) 1978-01-24
IL52117A (en) 1980-06-30
NL189609C (nl) 1993-06-01
SE438329B (sv) 1985-04-15
NL7706604A (nl) 1977-12-20
HU179966B (en) 1983-01-28
GB1584105A (en) 1981-02-04
IE45195L (en) 1977-12-16
FR2355005B1 (es) 1980-03-07
FR2355005A1 (fr) 1978-01-13
JPS6043339B2 (ja) 1985-09-27
IL52117A0 (en) 1977-07-31
AR219926A1 (es) 1980-09-30
NZ184136A (en) 1978-09-20
ATA423777A (de) 1979-02-15
PH13001A (en) 1979-11-09
DE2726394A1 (de) 1977-12-29
CH627161A5 (es) 1981-12-31
SE7706948L (sv) 1977-12-17
PL103103B1 (pl) 1979-05-31
NL189609B (nl) 1993-01-04

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