ES457805A1 - Un procedimiento para la preparacion de derivados de tiou- rea. - Google Patents
Un procedimiento para la preparacion de derivados de tiou- rea.Info
- Publication number
- ES457805A1 ES457805A1 ES457805A ES457805A ES457805A1 ES 457805 A1 ES457805 A1 ES 457805A1 ES 457805 A ES457805 A ES 457805A ES 457805 A ES457805 A ES 457805A ES 457805 A1 ES457805 A1 ES 457805A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- tiourea
- derivatives
- procedure
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003585 thioureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Ceramic Products (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67710676A | 1976-04-15 | 1976-04-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES457805A1 true ES457805A1 (es) | 1978-11-01 |
Family
ID=24717351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES457805A Expired ES457805A1 (es) | 1976-04-15 | 1977-04-14 | Un procedimiento para la preparacion de derivados de tiou- rea. |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US4066695A (OSRAM) |
| JP (1) | JPS52128332A (OSRAM) |
| AR (1) | AR218247A1 (OSRAM) |
| AT (1) | AT353282B (OSRAM) |
| AU (1) | AU509570B2 (OSRAM) |
| BE (1) | BE853578A (OSRAM) |
| DE (1) | DE2716838A1 (OSRAM) |
| DK (1) | DK165677A (OSRAM) |
| ES (1) | ES457805A1 (OSRAM) |
| FI (1) | FI771199A7 (OSRAM) |
| FR (1) | FR2350340A1 (OSRAM) |
| GB (1) | GB1579181A (OSRAM) |
| GR (1) | GR63193B (OSRAM) |
| HU (1) | HU176110B (OSRAM) |
| IE (1) | IE44425B1 (OSRAM) |
| IL (1) | IL51850A (OSRAM) |
| IT (1) | IT1075834B (OSRAM) |
| LU (1) | LU77137A1 (OSRAM) |
| MC (1) | MC1143A1 (OSRAM) |
| NL (1) | NL7704153A (OSRAM) |
| NO (1) | NO771309L (OSRAM) |
| NZ (1) | NZ183848A (OSRAM) |
| PH (1) | PH13392A (OSRAM) |
| PT (1) | PT66440B (OSRAM) |
| SE (1) | SE7704322L (OSRAM) |
| ZA (1) | ZA772083B (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1980000151A1 (en) * | 1978-07-03 | 1980-02-07 | American Home Prod | N-(3-alkylaminopropyl)-n'-phenylureas |
| US4224242A (en) * | 1978-07-03 | 1980-09-23 | American Home Products Corporation | N-[3-(lower)alkylaminopropyl]-N'-(disubstituted)phenylureas |
| US4290971A (en) * | 1979-01-19 | 1981-09-22 | Dso "Pharmachim" | Method of preparing 2-(phenylamino)-imidazolines-(2) |
| US4348413A (en) * | 1979-05-21 | 1982-09-07 | American Home Products Corporation | Anti-arrhythmic N-[3-alkylaminopropyl]-N'-phenylureas |
| EP0025010B1 (de) * | 1979-07-03 | 1983-07-20 | Ciba-Geigy Ag | Thioharnstoffderivate und Isothioharnstoffderivate, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Mittel und ihre Verwendung zur Bekämpfung von Schädlingen |
| US4328247A (en) * | 1979-09-19 | 1982-05-04 | Ciba-Geigy Corporation | Phenoxyphenylisothioureas, production thereof and use thereof in pest control, and phenoxyphenylthioureas as intermediates for the production of the phenoxyphenylisothioureas and use thereof in pest control |
| US4474707A (en) * | 1980-10-09 | 1984-10-02 | American Home Products Corporation | N-3-Propenylaminopropyl-N'-phenylureas |
| US4399286A (en) * | 1981-07-16 | 1983-08-16 | Mead Johnson & Company | Antiarrhythmic phenethylpiperidine compounds |
| US5593993A (en) * | 1991-08-02 | 1997-01-14 | Medivir Ab | Method for inhibition of HIV related viruses |
| IL102548A (en) * | 1991-08-02 | 1998-08-16 | Medivir Ab | Thiourea derivatives for use in the preparation of medicaments for the inhibition of hiv and the treatment of aids and some such novel compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2849306A (en) * | 1954-03-19 | 1958-08-26 | Du Pont | Herbicidal method and composition employing aryl pseudoureas |
| US3717633A (en) * | 1965-10-01 | 1973-02-20 | Boehringer Sohn Ingelheim | 2-anilino-1,3-diazacyclopentene-(2) derivative |
| DE1618158A1 (de) * | 1967-05-16 | 1970-10-29 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung neuer Guanidinderivate |
| US3950537A (en) * | 1973-06-29 | 1976-04-13 | Rohm And Haas Company | Gastrointestinally active thioureas |
-
1977
- 1977-01-27 US US05/763,189 patent/US4066695A/en not_active Expired - Lifetime
- 1977-01-27 US US05/763,172 patent/US4096276A/en not_active Expired - Lifetime
- 1977-04-05 ZA ZA00772083A patent/ZA772083B/xx unknown
- 1977-04-08 IL IL51850A patent/IL51850A/xx unknown
- 1977-04-13 MC MC771238A patent/MC1143A1/fr unknown
- 1977-04-13 NZ NZ183848A patent/NZ183848A/xx unknown
- 1977-04-13 GR GR53213A patent/GR63193B/el unknown
- 1977-04-13 FR FR7711082A patent/FR2350340A1/fr not_active Withdrawn
- 1977-04-14 GB GB15523/77A patent/GB1579181A/en not_active Expired
- 1977-04-14 AT AT262977A patent/AT353282B/de not_active IP Right Cessation
- 1977-04-14 SE SE7704322A patent/SE7704322L/xx unknown
- 1977-04-14 LU LU77137A patent/LU77137A1/xx unknown
- 1977-04-14 NO NO771309A patent/NO771309L/no unknown
- 1977-04-14 BE BE176697A patent/BE853578A/xx unknown
- 1977-04-14 IE IE775/77A patent/IE44425B1/en unknown
- 1977-04-14 DK DK165677A patent/DK165677A/da not_active IP Right Cessation
- 1977-04-14 HU HU77HO1973A patent/HU176110B/hu unknown
- 1977-04-14 JP JP4211977A patent/JPS52128332A/ja active Pending
- 1977-04-14 PT PT66440A patent/PT66440B/pt unknown
- 1977-04-14 AU AU24253/77A patent/AU509570B2/en not_active Expired
- 1977-04-14 AR AR267224A patent/AR218247A1/es active
- 1977-04-14 ES ES457805A patent/ES457805A1/es not_active Expired
- 1977-04-15 NL NL7704153A patent/NL7704153A/xx not_active Application Discontinuation
- 1977-04-15 FI FI771199A patent/FI771199A7/fi not_active Application Discontinuation
- 1977-04-15 PH PH19665A patent/PH13392A/en unknown
- 1977-04-15 IT IT22536/77A patent/IT1075834B/it active
- 1977-04-15 DE DE19772716838 patent/DE2716838A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ATA262977A (de) | 1979-04-15 |
| FR2350340A1 (fr) | 1977-12-02 |
| IT1075834B (it) | 1985-04-22 |
| DE2716838A1 (de) | 1977-10-27 |
| HU176110B (en) | 1980-12-28 |
| IE44425L (en) | 1977-10-15 |
| NZ183848A (en) | 1978-09-20 |
| JPS52128332A (en) | 1977-10-27 |
| NL7704153A (nl) | 1977-10-18 |
| NO771309L (no) | 1977-10-18 |
| PT66440B (en) | 1979-03-09 |
| LU77137A1 (OSRAM) | 1978-06-01 |
| AU2425377A (en) | 1978-10-19 |
| SE7704322L (sv) | 1977-10-16 |
| DK165677A (da) | 1977-10-16 |
| MC1143A1 (fr) | 1978-01-30 |
| GB1579181A (en) | 1980-11-12 |
| PT66440A (en) | 1977-05-01 |
| US4066695A (en) | 1978-01-03 |
| AU509570B2 (en) | 1980-05-15 |
| IE44425B1 (en) | 1981-11-18 |
| US4096276A (en) | 1978-06-20 |
| GR63193B (en) | 1979-10-04 |
| AT353282B (de) | 1979-11-12 |
| BE853578A (fr) | 1977-10-14 |
| PH13392A (en) | 1980-03-28 |
| FI771199A7 (OSRAM) | 1977-10-16 |
| IL51850A (en) | 1980-03-31 |
| AR218247A1 (es) | 1980-05-30 |
| ZA772083B (en) | 1978-03-29 |
| IL51850A0 (en) | 1977-06-30 |
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