ES453665A1 - Diazepine derivatives - Google Patents
Diazepine derivativesInfo
- Publication number
- ES453665A1 ES453665A1 ES453665A ES453665A ES453665A1 ES 453665 A1 ES453665 A1 ES 453665A1 ES 453665 A ES453665 A ES 453665A ES 453665 A ES453665 A ES 453665A ES 453665 A1 ES453665 A1 ES 453665A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- dihydro
- phenyl
- amino
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Novel 5-amino-7-phenyl-2,3-dihydro-1H-1,4-diazepines of the formula I are prepared. < IMAGE > R1, R2 and R3 are, independently of one another, hydrogen, an alkyl group with 1-4 carbon atoms, an alkoxy group with 1-4 carbon atoms, fluorine, chlorine or bromine, or two of the substituents R1, R2 and R3, which are located on adjacent carbon atoms, represent a methylenedioxy group. The compounds of the formula Ia < IMAGE > in which R1 is t-butyl are heated in the presence of free acid for this purpose. The compounds are active against obesity and have an antidiabetic effect. 5-Amino-7-phenyl-2,3-dihydro-1H-1,4-diazepine is preferred.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US456017A US3929884A (en) | 1974-03-29 | 1974-03-29 | Intermediates in the synthesis of 5-alkylamino-7-phenyl or substituted phenyl-2,3-dihydro-1H-1,4-diazepines |
US52834474A | 1974-11-29 | 1974-11-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES453665A1 true ES453665A1 (en) | 1977-11-16 |
Family
ID=27038065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES453665A Expired ES453665A1 (en) | 1974-03-29 | 1976-11-25 | Diazepine derivatives |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS5136482A (en) |
AU (1) | AU500509B2 (en) |
CA (1) | CA1064488A (en) |
CH (1) | CH613696A5 (en) |
DE (1) | DE2512510A1 (en) |
DK (1) | DK137127B (en) |
ES (1) | ES453665A1 (en) |
FI (1) | FI750827A (en) |
FR (1) | FR2265397B1 (en) |
GB (1) | GB1494433A (en) |
IE (1) | IE40951B1 (en) |
IL (1) | IL46958A (en) |
NL (1) | NL7503532A (en) |
NO (1) | NO750978L (en) |
SE (1) | SE7503278L (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0608655D0 (en) * | 2006-05-03 | 2006-06-14 | Merck Sharp & Dohme | Therapeutic Treatment |
-
1975
- 1975-03-19 CH CH349975A patent/CH613696A5/en not_active IP Right Cessation
- 1975-03-20 DK DK117975AA patent/DK137127B/en unknown
- 1975-03-20 FI FI750827A patent/FI750827A/fi not_active Application Discontinuation
- 1975-03-21 SE SE7503278A patent/SE7503278L/xx unknown
- 1975-03-21 NO NO750978A patent/NO750978L/no unknown
- 1975-03-21 DE DE19752512510 patent/DE2512510A1/en not_active Withdrawn
- 1975-03-25 NL NL7503532A patent/NL7503532A/en not_active Application Discontinuation
- 1975-03-26 FR FR7509428A patent/FR2265397B1/fr not_active Expired
- 1975-03-27 AU AU79601/75A patent/AU500509B2/en not_active Expired
- 1975-03-27 GB GB12866/75A patent/GB1494433A/en not_active Expired
- 1975-03-27 CA CA223,292A patent/CA1064488A/en not_active Expired
- 1975-03-27 IE IE699/75A patent/IE40951B1/en unknown
- 1975-03-27 JP JP50036157A patent/JPS5136482A/en active Pending
- 1975-03-28 IL IL46958A patent/IL46958A/en unknown
-
1976
- 1976-11-25 ES ES453665A patent/ES453665A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DK137127C (en) | 1978-06-26 |
NL7503532A (en) | 1975-10-01 |
AU500509B2 (en) | 1979-05-24 |
FI750827A (en) | 1975-09-21 |
IE40951L (en) | 1975-09-29 |
GB1494433A (en) | 1977-12-07 |
IE40951B1 (en) | 1979-09-12 |
DK137127B (en) | 1978-01-23 |
NO750978L (en) | 1975-09-30 |
SE7503278L (en) | 1975-09-30 |
CH613696A5 (en) | 1979-10-15 |
DE2512510A1 (en) | 1975-10-02 |
DK117975A (en) | 1975-09-30 |
IL46958A (en) | 1978-07-31 |
FR2265397B1 (en) | 1978-08-04 |
AU7960175A (en) | 1976-09-30 |
CA1064488A (en) | 1979-10-16 |
FR2265397A1 (en) | 1975-10-24 |
JPS5136482A (en) | 1976-03-27 |
IL46958A0 (en) | 1975-05-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES467565A1 (en) | 1-(4-Acylamino-phenyl)-2-amino-ethanols and salts thereof | |
ES391026A1 (en) | Benzonaphthyridine derivatives | |
ES405983A1 (en) | N-fluoroalkylated phenylethylamine | |
ES440426A1 (en) | Thienothiazines | |
JPS5637244B2 (en) | ||
AU562515B2 (en) | Pyridinecarbinols | |
ES448175A1 (en) | Propargyl-substituted 2-phenylamino-2-imidazolines and salts thereof | |
ES404598A1 (en) | 2-alkylamino-' -phenyl-1-cyclohexene-1-methyleneimine, its salts and preparation | |
ES453665A1 (en) | Diazepine derivatives | |
ES438044A1 (en) | 2-Amino-1,3-thiazines their use and preparation | |
IE790996L (en) | Phenylaminothiophene derivatives | |
ES475457A1 (en) | 2-(Pyridyl-amino)-benzoic acids and salts thereof | |
ES436317A1 (en) | 3-Piperazino-isoquinolines and salts thereof | |
CS137083A2 (en) | Zpusob vyroby novych bazicky substituovanych 4 fenyl 4,5,6,7 tetrahydrothieno ( 2,3 c ) pyridinu | |
ES470751A1 (en) | Morpholino pyridazinylhydrazones | |
ES456400A1 (en) | Thienothiazine derivatives | |
ES475596A1 (en) | Phenoxyalkanolamine derivatives | |
ES446329A1 (en) | Acetamidoxime compounds | |
ES457260A1 (en) | Derivatives of dithiepino{8 1,4{9 {8 2,3-C{9 pyrrole | |
ES465560A1 (en) | Phenylalkylamino-alkyl derivatives of quinazolinone and phthalazinone | |
ES451696A1 (en) | Pyrazolone derivatives and their use as herbicides | |
ES482437A1 (en) | 4H-s-Triazolo[3,4-c]thieno[2,3-e] 1,4-diazepines | |
ES442327A1 (en) | Hydrodipyrano-phthalazine compounds | |
SE7607818L (en) | WAY TO PREPARE NEW PHENOXIALKYLAMINE PYRIDYLETERS | |
ES439006A1 (en) | Procedure for the obtaining of new derivatives of 2-arilamino-2-imidazoline. (Machine-translation by Google Translate, not legally binding) |