ES452392A1 - Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES452392A1
ES452392A1 ES452392A ES452392A ES452392A1 ES 452392 A1 ES452392 A1 ES 452392A1 ES 452392 A ES452392 A ES 452392A ES 452392 A ES452392 A ES 452392A ES 452392 A1 ES452392 A1 ES 452392A1
Authority
ES
Spain
Prior art keywords
formula
arilalcohylamins
translation
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES452392A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES452392A1 publication Critical patent/ES452392A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

Compounds of the formula I are prepared by reacting a compound of the formula II with an appropriately substituted phenylethyl derivative which has a group which can undergo nucleophilic exchange. The symbols in the formulae have the meaning stated in Claim 1. When R4 in formula I is hydrogen, a compound with R4 = lower alkyl can be obtained by alkylation. The compounds of the formula I and their acid addition salts have mild blood pressure-lowering and selective heart rate-lowering effects.
ES452392A 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding) Expired ES452392A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752558273 DE2558273A1 (en) 1975-12-23 1975-12-23 NEW PROCESSES FOR THE PRODUCTION OF ARYLALKYLAMINES

Publications (1)

Publication Number Publication Date
ES452392A1 true ES452392A1 (en) 1977-11-01

Family

ID=5965417

Family Applications (6)

Application Number Title Priority Date Filing Date
ES452397A Expired ES452397A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)
ES452394A Expired ES452394A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)
ES452392A Expired ES452392A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)
ES452396A Expired ES452396A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)
ES452393A Expired ES452393A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)
ES452395A Expired ES452395A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES452397A Expired ES452397A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)
ES452394A Expired ES452394A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES452396A Expired ES452396A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)
ES452393A Expired ES452393A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)
ES452395A Expired ES452395A1 (en) 1975-12-23 1976-10-14 Procedure for the preparation of new substitute arilalcohylamins. (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
CH (6) CH627165A5 (en)
DE (1) DE2558273A1 (en)
ES (6) ES452397A1 (en)
SU (1) SU615855A3 (en)

Also Published As

Publication number Publication date
ES452396A1 (en) 1977-11-01
ES452393A1 (en) 1977-11-01
DE2558273A1 (en) 1977-07-14
ES452397A1 (en) 1977-11-01
ES452394A1 (en) 1977-11-01
ES452395A1 (en) 1977-11-01
CH626606A5 (en) 1981-11-30
CH626608A5 (en) 1981-11-30
CH627450A5 (en) 1982-01-15
CH627165A5 (en) 1981-12-31
CH627164A5 (en) 1981-12-31
SU615855A3 (en) 1978-07-15
CH626607A5 (en) 1981-11-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103