ES451772A1 - Dibenzo(b,e)-(1,4)diazepines - Google Patents

Dibenzo(b,e)-(1,4)diazepines

Info

Publication number
ES451772A1
ES451772A1 ES451772A ES451772A ES451772A1 ES 451772 A1 ES451772 A1 ES 451772A1 ES 451772 A ES451772 A ES 451772A ES 451772 A ES451772 A ES 451772A ES 451772 A1 ES451772 A1 ES 451772A1
Authority
ES
Spain
Prior art keywords
carbon atoms
diazepines
dibenzo
alkoxyalkyl
hydroxyalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES451772A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1241375A external-priority patent/CH599196A5/en
Priority claimed from CH1241475A external-priority patent/CH602709A5/en
Priority claimed from CH725076A external-priority patent/CH602708A5/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES451772A1 publication Critical patent/ES451772A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Electroplating Methods And Accessories (AREA)

Abstract

A process for the production of dibenzo [b, e] [1,4] diazepines, of formula I, ** (Formula) ** wherein R1 is hydrogen, alkyl of 1 to 4 carbon atoms, hydroxyalkyl of 2 to 4 carbon atoms or alkoxyalkyl of 2 to 5 carbon atoms in total, R2 is fluorine or chlorine, and R3 is alkyl of 1 to 4 carbon atoms, hydroxyalkyl of 2 to 4 carbon atoms, alkoxyalkyl of 2 to 5 carbon atoms total. Or 3 or 4 carbon alkenyl, provided that when R3 is methyl, then R2 is fluorine. (Machine-translation by Google Translate, not legally binding)
ES451772A 1975-09-24 1976-09-22 Dibenzo(b,e)-(1,4)diazepines Expired ES451772A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1241375A CH599196A5 (en) 1975-09-24 1975-09-24 (11)-Piperazinyl dibenzo-(b,e) (1,4)-diazepine derivs.
CH1241475A CH602709A5 (en) 1975-09-24 1975-09-24 (11)-Piperazinyl dibenzo-(b,e) (1,4)-diazepine derivs.
CH725076A CH602708A5 (en) 1976-06-09 1976-06-09 (11)-Piperazinyl dibenzo-(b,e) (1,4)-diazepine derivs.

Publications (1)

Publication Number Publication Date
ES451772A1 true ES451772A1 (en) 1978-01-01

Family

ID=27175741

Family Applications (1)

Application Number Title Priority Date Filing Date
ES451772A Expired ES451772A1 (en) 1975-09-24 1976-09-22 Dibenzo(b,e)-(1,4)diazepines

Country Status (16)

Country Link
JP (1) JPS5239689A (en)
AU (1) AU1808576A (en)
DE (1) DE2641378A1 (en)
DK (1) DK416476A (en)
ES (1) ES451772A1 (en)
FI (1) FI762646A (en)
FR (1) FR2325381A1 (en)
GB (1) GB1554275A (en)
IE (1) IE43727B1 (en)
IL (1) IL50531A0 (en)
NL (1) NL7610420A (en)
NO (1) NO763172L (en)
NZ (1) NZ182137A (en)
PT (1) PT65629B (en)
SE (1) SE7610219L (en)
SU (1) SU668602A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991010661A1 (en) * 1990-01-11 1991-07-25 Novokuznetsky Nauchno-Issledovatelsky Khimiko-Farmatsevtichesky Institut DERIVATIVES OF 5-AMINO-8-CHLORINE-DIBENZO[b,e][1,4]-DIAZEPINE AND A PHARMACEUTICAL PREPARATION FOR TREATMENT OF EPILEPSY AND EPILEPTIC STATUS BASED THEREON
US6034078A (en) * 1992-05-29 2000-03-07 Eli Lilly And Company Limited Thienobenzodiazepine compounds
NO305125B1 (en) * 1992-05-29 1999-04-06 Lilly Industries Ltd Pharmaceutical compounds
ES2324713T3 (en) 2003-12-22 2009-08-13 Acadia Pharmaceuticals Inc. DIARIL ANALOGS (A, D) AMINO-SUBSTITUTED CYCLHEPTENE AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS.
WO2013070107A1 (en) * 2011-11-09 2013-05-16 Общество С Ограниченной Ответственностью "Валентек" 5h-dibenzo[b,e][1,4]diazepine derivatives and use thereof

Also Published As

Publication number Publication date
NZ182137A (en) 1978-12-18
IE43727B1 (en) 1981-05-06
NL7610420A (en) 1977-03-28
DK416476A (en) 1977-03-25
FR2325381A1 (en) 1977-04-22
PT65629B (en) 1978-05-10
AU1808576A (en) 1978-04-06
PT65629A (en) 1976-10-01
GB1554275A (en) 1979-10-17
NO763172L (en) 1977-03-25
DE2641378A1 (en) 1977-04-07
FI762646A (en) 1977-03-25
JPS5239689A (en) 1977-03-28
IE43727L (en) 1977-03-24
IL50531A0 (en) 1976-11-30
SU668602A3 (en) 1979-06-15
SE7610219L (en) 1977-03-25
FR2325381B1 (en) 1978-11-17

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