ES482442A1 - 4H-s-Triazolo[3,4-c]thieno[2,3-e] 1,4-diazepines - Google Patents

4H-s-Triazolo[3,4-c]thieno[2,3-e] 1,4-diazepines

Info

Publication number
ES482442A1
ES482442A1 ES482442A ES482442A ES482442A1 ES 482442 A1 ES482442 A1 ES 482442A1 ES 482442 A ES482442 A ES 482442A ES 482442 A ES482442 A ES 482442A ES 482442 A1 ES482442 A1 ES 482442A1
Authority
ES
Spain
Prior art keywords
bromine
chlorine
alkyl
hydrogen
diazepines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES482442A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES482442A1 publication Critical patent/ES482442A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Compounds of general formula (I> < IMAGE > (wherein R2 is hydrogen, fluorine, chlorine or bromine R3 is chlorine, bromine or alkyl and R4 and R5 independently are hydrogen, alkyl, or hydroxyalkyl, or, together with the nitrogen atom to which they are attached, form a 5- or 6-membered saturated heterocyclic ring optionally substituted by one or two methyl groups and when a 6-membered ring, optionally containing an oxygen atom) exhibit neuroleptic activity and show tranquilizing, anxiolytic and/or tensiolytic properties.
ES482442A 1978-07-13 1979-07-12 4H-s-Triazolo[3,4-c]thieno[2,3-e] 1,4-diazepines Expired ES482442A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782830782 DE2830782A1 (en) 1978-07-13 1978-07-13 NEW SUBSTITUTED 4H-S-TRIAZOLO ANGLE CLAMP ON 3.4C ANGLE CLAMP ON THIENO ANGLE CLAMP ON 2.3E ANGLE CLAMP ON 1,4-DIAZEPINE, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS

Publications (1)

Publication Number Publication Date
ES482442A1 true ES482442A1 (en) 1980-04-01

Family

ID=6044278

Family Applications (2)

Application Number Title Priority Date Filing Date
ES482442A Expired ES482442A1 (en) 1978-07-13 1979-07-12 4H-s-Triazolo[3,4-c]thieno[2,3-e] 1,4-diazepines
ES482437A Expired ES482437A1 (en) 1978-07-13 1979-07-12 4H-s-Triazolo[3,4-c]thieno[2,3-e] 1,4-diazepines

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES482437A Expired ES482437A1 (en) 1978-07-13 1979-07-12 4H-s-Triazolo[3,4-c]thieno[2,3-e] 1,4-diazepines

Country Status (25)

Country Link
JP (1) JPS5513297A (en)
AT (1) AT370735B (en)
BE (1) BE877669A (en)
BG (1) BG34451A3 (en)
CS (1) CS209929B2 (en)
DD (1) DD144777A5 (en)
DE (1) DE2830782A1 (en)
DK (1) DK295179A (en)
ES (2) ES482442A1 (en)
FI (1) FI792185A (en)
FR (1) FR2430949A1 (en)
GB (1) GB2029408B (en)
GR (1) GR69815B (en)
HU (1) HU177960B (en)
IL (1) IL57776A (en)
IT (1) IT1188845B (en)
LU (1) LU81494A1 (en)
NL (1) NL7905483A (en)
NO (1) NO792319L (en)
PL (1) PL120417B1 (en)
PT (1) PT69910A (en)
RO (1) RO78104A (en)
SE (1) SE7906093L (en)
SU (1) SU833160A3 (en)
ZA (1) ZA793509B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
DE540766T1 (en) * 1991-11-04 2002-11-28 Ruth-Maria Korth Treatment of eosinophil-mediated diseases with PAF antagonists, and method for determining their effectiveness.
DE69133083C5 (en) * 1991-11-04 2007-05-31 Korth, Ruth-Maria, Dr.med. Treatment and prevention of elevated lyso-PAF levels mediated mental illnesses with PAF antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709899A (en) * 1971-04-28 1973-01-09 Upjohn Co 6-phenyl-4h-s-triazolo(4,3-a)(1,4)benzodiazepines and their production
AT338799B (en) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim PROCESS FOR PREPARING NEW SUBSTITUTED 6-ARYL-4H-S-TRIAZOLO- (3,4C) -THIENO- (2,3E) -1,4-DIAZEPINE AND THEIR SALTS
FI63033C (en) * 1977-07-21 1983-04-11 Boehringer Sohn Ingelheim FREQUENCY REQUIREMENT FOR ANXIOLYTIC TRANSQUILLATION OF SEED / ELLER NEUROLEPTIC SUBSTITUTES 1-PIPERAZINYL-4H-S-TRIAZOLO (3,4-C) THIENO (2,3-E) -1,4-DIAZEPERE

Also Published As

Publication number Publication date
IT7949724A0 (en) 1979-07-11
SE7906093L (en) 1980-01-14
HU177960B (en) 1982-02-28
ES482437A1 (en) 1980-04-01
BE877669A (en) 1980-01-14
FR2430949A1 (en) 1980-02-08
BG34451A3 (en) 1983-09-15
IT1188845B (en) 1988-01-28
AT370735B (en) 1983-04-25
NL7905483A (en) 1980-01-15
ATA465279A (en) 1982-09-15
PL120417B1 (en) 1982-02-27
NO792319L (en) 1980-01-15
FR2430949B1 (en) 1982-11-05
IL57776A (en) 1983-06-15
DK295179A (en) 1980-01-14
IL57776A0 (en) 1979-11-30
RO78104A (en) 1982-02-01
GB2029408A (en) 1980-03-19
SU833160A3 (en) 1981-05-23
LU81494A1 (en) 1980-08-08
JPS5513297A (en) 1980-01-30
PT69910A (en) 1979-08-01
GR69815B (en) 1982-07-13
ZA793509B (en) 1981-03-25
DD144777A5 (en) 1980-11-05
PL217029A1 (en) 1980-08-11
DE2830782A1 (en) 1980-01-24
CS209929B2 (en) 1981-12-31
GB2029408B (en) 1982-07-28
FI792185A (en) 1980-01-14

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