ES446239A1 - Procedimiento para preparar un derivado de prostaglandina. - Google Patents

Procedimiento para preparar un derivado de prostaglandina.

Info

Publication number
ES446239A1
ES446239A1 ES446239A ES446239A ES446239A1 ES 446239 A1 ES446239 A1 ES 446239A1 ES 446239 A ES446239 A ES 446239A ES 446239 A ES446239 A ES 446239A ES 446239 A1 ES446239 A1 ES 446239A1
Authority
ES
Spain
Prior art keywords
formula
prostaglandin derivative
azaprostaglandins
preparation
see
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES446239A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Publication of ES446239A1 publication Critical patent/ES446239A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185Saturated compounds having only one carboxyl group and containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES446239A 1975-03-21 1976-03-20 Procedimiento para preparar un derivado de prostaglandina. Expired ES446239A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB12034/75A GB1529852A (en) 1975-03-21 1975-03-21 8-azaprostaglandins and process for the preparation thereof

Publications (1)

Publication Number Publication Date
ES446239A1 true ES446239A1 (es) 1977-07-01

Family

ID=9997230

Family Applications (2)

Application Number Title Priority Date Filing Date
ES446239A Expired ES446239A1 (es) 1975-03-21 1976-03-20 Procedimiento para preparar un derivado de prostaglandina.
ES458389A Expired ES458389A1 (es) 1975-03-21 1977-05-03 Procedimiento para preparar derivados de prostaglandina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES458389A Expired ES458389A1 (es) 1975-03-21 1977-05-03 Procedimiento para preparar derivados de prostaglandina.

Country Status (26)

Country Link
JP (1) JPS607602B2 (ru)
AR (1) AR213172A1 (ru)
AT (1) AT348163B (ru)
AU (1) AU501105B2 (ru)
BE (1) BE839761A (ru)
CA (1) CA1076587A (ru)
CH (2) CH611881A5 (ru)
DE (1) DE2612114A1 (ru)
DK (1) DK140937B (ru)
ES (2) ES446239A1 (ru)
FI (1) FI61692C (ru)
FR (1) FR2304340A1 (ru)
GB (1) GB1529852A (ru)
HU (1) HU173348B (ru)
IE (1) IE42966B1 (ru)
IT (1) IT1061011B (ru)
MX (1) MX3301E (ru)
NL (1) NL7602891A (ru)
NO (1) NO144147C (ru)
NZ (1) NZ180251A (ru)
OA (1) OA05279A (ru)
PT (1) PT64919B (ru)
SE (1) SE418290B (ru)
SU (1) SU614746A3 (ru)
YU (1) YU73876A (ru)
ZA (1) ZA761448B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097489A (en) * 1977-06-17 1978-06-27 The Upjohn Company 9-Deoxy-9α,6-nitrilo or 6,9α-imino-PGF compounds
US5540618A (en) * 1994-10-28 1996-07-30 National University Of Singapore Passive attenuator for shelter protection against explosions
WO2003074483A1 (fr) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif

Also Published As

Publication number Publication date
FR2304340A1 (fr) 1976-10-15
FI760744A (ru) 1976-09-22
GB1529852A (en) 1978-10-25
FI61692C (fi) 1982-09-10
JPS51138671A (en) 1976-11-30
DE2612114A1 (de) 1976-10-07
DK140937C (ru) 1980-05-19
FR2304340B1 (ru) 1979-06-29
ATA195676A (de) 1978-06-15
DK88276A (ru) 1976-09-22
PT64919A (en) 1976-04-01
CH611604A5 (en) 1979-06-15
OA05279A (fr) 1981-02-28
HU173348B (hu) 1979-04-28
ES458389A1 (es) 1978-02-16
IE42966B1 (en) 1980-11-19
BE839761A (fr) 1976-09-20
CA1076587A (en) 1980-04-29
AU1189976A (en) 1977-09-15
IT1061011B (it) 1982-10-20
YU73876A (en) 1982-10-31
NO144147C (no) 1981-07-15
PT64919B (en) 1977-08-24
JPS607602B2 (ja) 1985-02-26
NZ180251A (en) 1978-07-28
NO760994L (ru) 1976-09-22
MX3301E (es) 1980-09-03
IE42966L (en) 1976-09-21
AU501105B2 (en) 1979-06-14
CH611881A5 (en) 1979-06-29
NL7602891A (nl) 1976-09-23
AR213172A1 (es) 1978-12-29
SU614746A3 (ru) 1978-07-05
SE7603400L (sv) 1976-09-22
AT348163B (de) 1979-02-12
NO144147B (no) 1981-03-23
ZA761448B (en) 1977-03-30
FI61692B (fi) 1982-05-31
DK140937B (da) 1979-12-10
SE418290B (sv) 1981-05-18

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