ES445793A1 - Phenoxyphenylbutyric acid derivatives and process for their preparation - Google Patents

Phenoxyphenylbutyric acid derivatives and process for their preparation

Info

Publication number
ES445793A1
ES445793A1 ES445793A ES445793A ES445793A1 ES 445793 A1 ES445793 A1 ES 445793A1 ES 445793 A ES445793 A ES 445793A ES 445793 A ES445793 A ES 445793A ES 445793 A1 ES445793 A1 ES 445793A1
Authority
ES
Spain
Prior art keywords
residue
formula
transformed
phenoxyphenylbutyric
coor1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES445793A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES445793A1 publication Critical patent/ES445793A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Procedure for obtaining derivatives of phenoxyphenylbutyric acid of general formula I ** (See formula) ** where R1 is H, C 1-6 -alkyl or CnH2n-R3, R2 is H, F, Cl or Br, R3 is 2-8 C-dialkylamino, pyrrolidino, piperidino, morpholino, piperazino, 4-alkylpiperazino or 4-hydroxyalkylpiperazine, in each case with 5-8 carbon atoms and n represents 2, 3 or 4, as well as their physiologically compatible salts, characterized in that in a compound of general formula II ** (See formula) ** where X means a transformable residue in the group -CH (CH3) -CH2-COOR1 and R1 and R2 have the meanings indicated in formula I, the residue X is transformed into the group -CH (CH3) -CH2-COOR1, and because, optionally, in a compound obtained of formula I, the residue is transformed by treatment with a solvolizing, esterifying or salt-forming agent in another residue R1, and/or a carboxylic acid obtained is transformed by treatment with a base in a physiologically compatible salt. (Machine-translation by Google Translate, not legally binding)
ES445793A 1975-03-07 1976-03-05 Phenoxyphenylbutyric acid derivatives and process for their preparation Expired ES445793A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752509891 DE2509891A1 (en) 1975-03-07 1975-03-07 PHENOXYPHENYL BUTTERIC ACID DERIVATIVES AND METHOD FOR THEIR PRODUCTION

Publications (1)

Publication Number Publication Date
ES445793A1 true ES445793A1 (en) 1977-09-01

Family

ID=5940676

Family Applications (1)

Application Number Title Priority Date Filing Date
ES445793A Expired ES445793A1 (en) 1975-03-07 1976-03-05 Phenoxyphenylbutyric acid derivatives and process for their preparation

Country Status (14)

Country Link
JP (1) JPS51125348A (en)
AT (1) ATA162476A (en)
AU (1) AU497104B2 (en)
BE (1) BE839211A (en)
DE (1) DE2509891A1 (en)
DK (1) DK97976A (en)
ES (1) ES445793A1 (en)
FR (1) FR2302731A1 (en)
GB (1) GB1494462A (en)
IE (1) IE42502B1 (en)
LU (1) LU74489A1 (en)
NL (1) NL7602341A (en)
SE (1) SE7602744L (en)
ZA (1) ZA761340B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6011483A (en) * 1983-06-29 1985-01-21 Taiho Yakuhin Kogyo Kk Piperazine compound

Also Published As

Publication number Publication date
NL7602341A (en) 1976-09-09
IE42502L (en) 1976-09-07
FR2302731A1 (en) 1976-10-01
LU74489A1 (en) 1977-09-27
BE839211A (en) 1976-09-06
SE7602744L (en) 1976-09-08
DK97976A (en) 1976-09-08
JPS51125348A (en) 1976-11-01
AU1155576A (en) 1977-09-08
IE42502B1 (en) 1980-08-27
ATA162476A (en) 1979-05-15
GB1494462A (en) 1977-12-07
AU497104B2 (en) 1978-11-30
ZA761340B (en) 1977-02-23
DE2509891A1 (en) 1976-09-23

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