ES445054A1 - Un procedimiento para la separacion de cefamicina o de las impurezas del caldo de fermentacion. - Google Patents

Un procedimiento para la separacion de cefamicina o de las impurezas del caldo de fermentacion.

Info

Publication number
ES445054A1
ES445054A1 ES445054A ES445054A ES445054A1 ES 445054 A1 ES445054 A1 ES 445054A1 ES 445054 A ES445054 A ES 445054A ES 445054 A ES445054 A ES 445054A ES 445054 A1 ES445054 A1 ES 445054A1
Authority
ES
Spain
Prior art keywords
fermentation broth
cefamycin
impurities
separation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES445054A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES445054A1 publication Critical patent/ES445054A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
ES445054A 1975-02-10 1976-02-10 Un procedimiento para la separacion de cefamicina o de las impurezas del caldo de fermentacion. Expired ES445054A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/548,466 US3983108A (en) 1975-02-10 1975-02-10 Antibiotic purification process

Publications (1)

Publication Number Publication Date
ES445054A1 true ES445054A1 (es) 1977-08-01

Family

ID=24188957

Family Applications (1)

Application Number Title Priority Date Filing Date
ES445054A Expired ES445054A1 (es) 1975-02-10 1976-02-10 Un procedimiento para la separacion de cefamicina o de las impurezas del caldo de fermentacion.

Country Status (7)

Country Link
US (1) US3983108A (enExample)
JP (1) JPS5830040B2 (enExample)
ES (1) ES445054A1 (enExample)
FR (1) FR2300092A1 (enExample)
GB (1) GB1492021A (enExample)
IE (1) IE42633B1 (enExample)
NL (1) NL7600552A (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196285A (en) * 1977-06-02 1980-04-01 Merck & Co., Inc. Antibiotic purification process
US4137405A (en) * 1977-07-28 1979-01-30 Merck & Co., Inc. Isolation of antibiotic Cephamycin C
US4205165A (en) * 1977-12-06 1980-05-27 Glaxo Group Limited Processing of cephalosporin C
JPS5540615A (en) * 1978-09-14 1980-03-22 Takeda Chem Ind Ltd Separation and purification of cephalosporins
CN101134760B (zh) * 2006-08-31 2010-05-12 上海医药工业研究院 去除粉末状头霉素c中色素的方法
CN103421024B (zh) * 2012-05-21 2016-08-03 上海医药工业研究院 制备头霉素c的方法
CN102993214B (zh) * 2012-12-07 2015-01-28 西北大学 一种头孢菌素的脱色方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3467654A (en) * 1966-08-19 1969-09-16 Lilly Co Eli Process for the recovery and purification of cephalosporin c
US3709880A (en) * 1970-12-09 1973-01-09 Merck & Co Inc Antibiotic purification process
US3733320A (en) * 1971-03-03 1973-05-15 Merck & Co Inc Antibiotic purification processes
JPS5318595B2 (enExample) * 1972-08-31 1978-06-15

Also Published As

Publication number Publication date
IE42633L (en) 1976-08-10
JPS5830040B2 (ja) 1983-06-27
GB1492021A (en) 1977-11-16
FR2300092A1 (fr) 1976-09-03
IE42633B1 (en) 1980-09-24
FR2300092B1 (enExample) 1979-06-22
US3983108A (en) 1976-09-28
NL7600552A (nl) 1976-08-12
JPS51106790A (en) 1976-09-21

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202