ES443415A1 - Procedimiento para la preparacion de nuevos derivados bife- niloxilicos. - Google Patents

Procedimiento para la preparacion de nuevos derivados bife- niloxilicos.

Info

Publication number
ES443415A1
ES443415A1 ES443415A ES443415A ES443415A1 ES 443415 A1 ES443415 A1 ES 443415A1 ES 443415 A ES443415 A ES 443415A ES 443415 A ES443415 A ES 443415A ES 443415 A1 ES443415 A1 ES 443415A1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
general formula
compound
carboxyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES443415A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752500692 external-priority patent/DE2500692C3/de
Priority claimed from DE19752547872 external-priority patent/DE2547872A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES443415A1 publication Critical patent/ES443415A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
ES443415A 1975-01-09 1975-12-11 Procedimiento para la preparacion de nuevos derivados bife- niloxilicos. Expired ES443415A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752500692 DE2500692C3 (de) 1975-01-09 Derivate des 4-Amidoalkylen-4'oxy diphenyle
DE19752547872 DE2547872A1 (de) 1975-10-25 1975-10-25 Verfahren zur herstellung von biphenyloxy-derivaten

Publications (1)

Publication Number Publication Date
ES443415A1 true ES443415A1 (es) 1977-04-16

Family

ID=25768333

Family Applications (1)

Application Number Title Priority Date Filing Date
ES443415A Expired ES443415A1 (es) 1975-01-09 1975-12-11 Procedimiento para la preparacion de nuevos derivados bife- niloxilicos.

Country Status (22)

Country Link
US (1) US4010279A (es)
JP (1) JPS5195047A (es)
AT (1) AT341512B (es)
CA (1) CA1061347A (es)
CS (1) CS188263B2 (es)
DD (1) DD125199A5 (es)
DK (1) DK5976A (es)
ES (1) ES443415A1 (es)
FI (1) FI753702A (es)
FR (1) FR2297037A1 (es)
GB (1) GB1501541A (es)
GR (1) GR59482B (es)
HU (1) HU172100B (es)
IL (1) IL48806A (es)
LU (1) LU74139A1 (es)
NL (1) NL7600144A (es)
NO (1) NO760054L (es)
PH (1) PH13633A (es)
PL (1) PL101301B1 (es)
PT (1) PT64680B (es)
RO (1) RO70525A (es)
SE (1) SE7600139L (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2517229A1 (de) * 1975-04-18 1976-10-28 Boehringer Mannheim Gmbh Phenylalkylcarbonsaeure-derivate und verfahren zu ihrer herstellung
DE2541342A1 (de) * 1975-09-17 1977-03-31 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben
DE2546996C2 (de) * 1975-10-21 1984-07-05 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäure-Derivate, Verfahren zur Herstellung derselben sowie Arzneimittel, die diese Verbindungen als Wirkstoff enthalten
US4214094A (en) * 1977-03-30 1980-07-22 Fujisawa Pharmaceutical Co., Ltd. Substituted-phenyl substituted-alkyl ethers and the preparation thereof
PE20000942A1 (es) * 1998-07-31 2000-09-28 Lilly Co Eli Derivados de amida, carbamato y urea
US6617351B1 (en) 1998-07-31 2003-09-09 Eli Lilly And Company Amide, carbamate, and urea derivatives
CN1703395A (zh) * 2002-08-09 2005-11-30 特兰斯泰克制药公司 芳基和杂芳基化合物以及调节凝血的方法
US7544699B2 (en) 2003-08-08 2009-06-09 Transtech Pharma, Inc. Aryl and heteroaryl compounds, compositions, and methods of use
WO2005014532A1 (en) 2003-08-08 2005-02-17 Transtech Pharma, Inc. Aryl and heteroaryl compounds, compositions and methods of use
US7208601B2 (en) 2003-08-08 2007-04-24 Mjalli Adnan M M Aryl and heteroaryl compounds, compositions, and methods of use
PL1836169T3 (pl) * 2004-12-28 2012-07-31 Kinex Pharmaceuticals Llc Kompozycje i sposoby leczenia zaburzeń związanych z proliferacją komórek
US7968574B2 (en) * 2004-12-28 2011-06-28 Kinex Pharmaceuticals, Llc Biaryl compositions and methods for modulating a kinase cascade
CN101595084B (zh) * 2006-06-29 2013-01-02 金克斯医药品有限公司 用于调整激酶级联的二芳基组合物和方法
US7935697B2 (en) * 2006-12-28 2011-05-03 Kinex Pharmaceuticals, Llc Compositions for modulating a kinase cascade and methods of use thereof
US7939529B2 (en) * 2007-05-17 2011-05-10 Kinex Pharmaceuticals, Llc Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof
US8124605B2 (en) * 2007-07-06 2012-02-28 Kinex Pharmaceuticals, Llc Compositions and methods for modulating a kinase cascade
CA2703615C (en) * 2007-10-20 2017-09-19 Kinex Pharmaceuticals, Llc Pharmaceutical compositions for modulating a kinase cascade and methods of use thereof
WO2011129936A2 (en) 2010-04-16 2011-10-20 Kinex Pharmaceuticals, Llc Compositions and methods for the prevention and treatment of cancer
US9926273B2 (en) 2012-08-30 2018-03-27 Athenex, Inc. Composition and methods for modulating a kinase cascade

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
DE2230383C3 (de) * 1971-10-01 1981-12-03 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäurederivate und Verfahren zur Herstellung derselben

Also Published As

Publication number Publication date
FR2297037B1 (es) 1979-09-21
HU172100B (hu) 1978-05-28
CA1061347A (en) 1979-08-28
IL48806A0 (en) 1976-03-31
SE7600139L (sv) 1976-07-12
PL101301B1 (pl) 1978-12-30
CS188263B2 (en) 1979-02-28
FR2297037A1 (fr) 1976-08-06
US4010279A (en) 1977-03-01
DK5976A (da) 1976-07-10
AU1011476A (en) 1977-07-14
AT341512B (de) 1978-02-10
IL48806A (en) 1978-10-31
DD125199A5 (es) 1977-04-06
GR59482B (en) 1978-01-30
NO760054L (es) 1976-07-12
PT64680B (fr) 1978-01-04
LU74139A1 (es) 1977-03-18
NL7600144A (nl) 1976-07-13
PH13633A (en) 1980-08-14
FI753702A (es) 1976-07-10
RO70525A (ro) 1981-09-24
JPS5195047A (es) 1976-08-20
PT64680A (fr) 1976-05-01
GB1501541A (en) 1978-02-15
ATA886775A (de) 1977-06-15

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