ES438303A1 - Procedimiento para preparar derivados de benzo (b) tiofeno. - Google Patents
Procedimiento para preparar derivados de benzo (b) tiofeno.Info
- Publication number
- ES438303A1 ES438303A1 ES438303A ES438303A ES438303A1 ES 438303 A1 ES438303 A1 ES 438303A1 ES 438303 A ES438303 A ES 438303A ES 438303 A ES438303 A ES 438303A ES 438303 A1 ES438303 A1 ES 438303A1
- Authority
- ES
- Spain
- Prior art keywords
- thiophene derivatives
- procedure
- preparing benzo
- benzo
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004802 benzothiophens Chemical class 0.000 title abstract 2
- -1 dimethylamino, diethylamino, di-n-propylamino Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2525674A GB1456323A (en) | 1974-06-06 | 1974-06-06 | Benzothiophenes process for preparing them and pharmaceutical compositions containing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
ES438303A1 true ES438303A1 (es) | 1977-01-16 |
Family
ID=10224753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES438303A Expired ES438303A1 (es) | 1974-06-06 | 1975-06-06 | Procedimiento para preparar derivados de benzo (b) tiofeno. |
Country Status (20)
Country | Link |
---|---|
US (1) | US4007204A (en:Method) |
JP (1) | JPS516958A (en:Method) |
AR (2) | AR207152A1 (en:Method) |
AT (1) | AT341517B (en:Method) |
BE (1) | BE829837A (en:Method) |
CA (1) | CA1030972A (en:Method) |
CH (1) | CH605910A5 (en:Method) |
DE (1) | DE2522655A1 (en:Method) |
DK (1) | DK135808B (en:Method) |
ES (1) | ES438303A1 (en:Method) |
FI (1) | FI751602A7 (en:Method) |
GB (1) | GB1456323A (en:Method) |
HU (1) | HU172820B (en:Method) |
IT (1) | IT1038094B (en:Method) |
NL (1) | NL7504921A (en:Method) |
NO (1) | NO751989L (en:Method) |
OA (1) | OA05022A (en:Method) |
SE (1) | SE7505482L (en:Method) |
SU (1) | SU578002A3 (en:Method) |
ZA (1) | ZA752871B (en:Method) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU509682B2 (en) * | 1975-10-28 | 1980-05-22 | Eli Lilly And Company | 2-Aroyl-3-Phenylbenzothiophene Derivatives |
US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
US5175184A (en) * | 1982-10-19 | 1992-12-29 | Kotobuki Seiyaku Company Limited | Benzothiophene derivatives and antihyperuricemia thereof |
NZ213986A (en) * | 1984-10-30 | 1989-07-27 | Usv Pharma Corp | Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such |
US4851554A (en) * | 1987-04-06 | 1989-07-25 | University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
US4806663A (en) * | 1987-04-06 | 1989-02-21 | The University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
US4912642A (en) * | 1987-09-03 | 1990-03-27 | The Boeing Company | Coordinated engine autothrottle |
US4831156A (en) * | 1987-09-30 | 1989-05-16 | The University Of Tennessee Research Corp. | 3-substituted 2-alkyl indole derivatives |
WO1989002893A1 (en) * | 1987-09-30 | 1989-04-06 | The University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzothiophene derivatives |
JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
ATE214059T1 (de) * | 1994-04-11 | 2002-03-15 | Chugai Pharmaceutical Co Ltd | 4,6-di-t-butyl-2,3-dihydrobenzothiophene, die ldl oxidation hemmen |
CO4410190A1 (es) * | 1994-09-19 | 1997-01-09 | Lilly Co Eli | 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO |
US6653328B1 (en) * | 1995-03-10 | 2003-11-25 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
US6417199B1 (en) * | 1995-03-10 | 2002-07-09 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
DE69634045T2 (de) | 1995-10-31 | 2005-05-19 | Eli Lilly And Co., Indianapolis | Antithrombotische diamine |
EP0888331A4 (en) * | 1996-03-19 | 2001-05-23 | Lilly Co Eli | SYNTHESIS OF 3- [4- (2-AMINOETHOXY) BENZOYL] -2-ARYL-6-HYDROXY-BENZO [b] THIOPHENES |
AU7170898A (en) | 1997-04-30 | 1998-11-24 | Eli Lilly And Company | Antithrombotic agents |
US6391901B1 (en) | 1997-04-30 | 2002-05-21 | Eli Lilly And Company | Thrombin inhibitors |
AU7165398A (en) * | 1997-04-30 | 1998-11-24 | Eli Lilly And Company | A regioselective alkylation process for preparing substituted benzo{b}thiophenes |
DE69824410T2 (de) | 1997-04-30 | 2005-06-02 | Eli Lilly And Co., Indianapolis | Antithrombosemittel |
US6350774B1 (en) | 1997-04-30 | 2002-02-26 | Eli Lilly And Company | Antithrombotic agents |
US6284756B1 (en) | 1998-04-30 | 2001-09-04 | Eli Lilly And Company | Antithrombotic agents |
PT997460E (pt) * | 1998-10-28 | 2003-03-31 | Lilly Co Eli | Compostos benzotiofenos como agentes antitromboticos e seus intermediarios |
FR2864536B1 (fr) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
JP6030556B2 (ja) * | 2010-08-06 | 2016-11-24 | タスリー・ファーマシューティカル・グループ・カンパニー・リミテッドTasly Pharmaceutical Group Co., Ltd. | 冠動脈心疾患の二次予防薬の調製におけるタンジン組成物の使用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3514465A (en) * | 1966-12-30 | 1970-05-26 | Degussa | Certain thiazolyl- and pyridinylaminoketones |
US3706747A (en) * | 1970-06-05 | 1972-12-19 | Pfizer | Benzothieno(3,2-d)- and benzofuro(3,2-d)pyrimidines |
-
1974
- 1974-06-06 GB GB2525674A patent/GB1456323A/en not_active Expired
-
1975
- 1975-01-01 AR AR258913A patent/AR207152A1/es active
- 1975-04-21 US US05/569,819 patent/US4007204A/en not_active Expired - Lifetime
- 1975-04-25 NL NL7504921A patent/NL7504921A/xx not_active Application Discontinuation
- 1975-05-02 ZA ZA00752871A patent/ZA752871B/xx unknown
- 1975-05-13 SE SE7505482A patent/SE7505482L/xx unknown
- 1975-05-14 IT IT23297/75A patent/IT1038094B/it active
- 1975-05-22 DE DE19752522655 patent/DE2522655A1/de active Pending
- 1975-05-30 FI FI751602A patent/FI751602A7/fi not_active Application Discontinuation
- 1975-05-30 HU HU75LA00000867A patent/HU172820B/hu unknown
- 1975-06-04 BE BE157003A patent/BE829837A/xx unknown
- 1975-06-04 DK DK251975AA patent/DK135808B/da unknown
- 1975-06-05 SU SU7502143254A patent/SU578002A3/ru active
- 1975-06-05 NO NO751989A patent/NO751989L/no unknown
- 1975-06-06 OA OA55520A patent/OA05022A/xx unknown
- 1975-06-06 CA CA228,687A patent/CA1030972A/en not_active Expired
- 1975-06-06 CH CH730375A patent/CH605910A5/xx not_active IP Right Cessation
- 1975-06-06 JP JP50069021A patent/JPS516958A/ja active Pending
- 1975-06-06 AT AT431175A patent/AT341517B/de not_active IP Right Cessation
- 1975-06-06 ES ES438303A patent/ES438303A1/es not_active Expired
- 1975-11-07 AR AR261103A patent/AR210265A1/es active
Also Published As
Publication number | Publication date |
---|---|
HU172820B (hu) | 1978-12-28 |
DE2522655A1 (de) | 1975-12-18 |
DK135808C (en:Method) | 1977-11-28 |
NL7504921A (nl) | 1975-12-09 |
CH605910A5 (en:Method) | 1978-10-13 |
DK251975A (en:Method) | 1975-12-07 |
DK135808B (da) | 1977-06-27 |
AT341517B (de) | 1978-02-10 |
JPS516958A (en) | 1976-01-20 |
US4007204A (en) | 1977-02-08 |
ATA431175A (de) | 1977-06-15 |
SU578002A3 (ru) | 1977-10-25 |
AU8102275A (en) | 1976-11-11 |
IT1038094B (it) | 1979-11-20 |
ZA752871B (en) | 1976-04-28 |
SE7505482L (sv) | 1975-12-08 |
GB1456323A (en) | 1976-11-24 |
FI751602A7 (en:Method) | 1975-12-07 |
CA1030972A (en) | 1978-05-09 |
BE829837A (fr) | 1975-12-04 |
AR210265A1 (es) | 1977-07-15 |
AR207152A1 (es) | 1976-09-15 |
OA05022A (fr) | 1980-12-31 |
NO751989L (en:Method) | 1975-12-09 |
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