ES435757A1 - Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. - Google Patents
Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos.Info
- Publication number
- ES435757A1 ES435757A1 ES435757A ES435757A ES435757A1 ES 435757 A1 ES435757 A1 ES 435757A1 ES 435757 A ES435757 A ES 435757A ES 435757 A ES435757 A ES 435757A ES 435757 A1 ES435757 A1 ES 435757A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- amino
- hydrogen
- radical
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008430 aromatic amides Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 150000001204 N-oxides Chemical class 0.000 abstract 2
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000004442 acylamino group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 239000007800 oxidant agent Substances 0.000 abstract 2
- 125000005420 sulfonamido group Chemical group S(=O)(=O)(N*)* 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000005422 alkyl sulfonamido group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 239000004927 clay Substances 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- -1 formic or acetic Chemical class 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical class [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000001451 organic peroxides Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229930192474 thiophene Natural products 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB12572/74A GB1507462A (en) | 1974-03-21 | 1974-03-21 | N-heterocyclic substituted benzamides methods for their preparation and compositions containing them |
| GB3540274 | 1974-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES435757A1 true ES435757A1 (es) | 1977-04-01 |
Family
ID=26249107
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435757A Expired ES435757A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435754A Expired ES435754A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435756A Expired ES435756A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435753A Expired ES435753A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435755A Expired ES435755A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435754A Expired ES435754A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435756A Expired ES435756A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435753A Expired ES435753A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435755A Expired ES435755A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS584019B2 (OSRAM) |
| AR (1) | AR216043A1 (OSRAM) |
| CH (1) | CH602641A5 (OSRAM) |
| DK (1) | DK147854C (OSRAM) |
| ES (5) | ES435757A1 (OSRAM) |
| FI (1) | FI60200C (OSRAM) |
| FR (1) | FR2264530A1 (OSRAM) |
| KE (1) | KE2900A (OSRAM) |
| NL (1) | NL159660B (OSRAM) |
| NO (1) | NO144108C (OSRAM) |
| SE (1) | SE427750B (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1513631A (en) * | 1976-02-17 | 1978-06-07 | Gallardo Antonio Sa | Piperidine derivatives |
| GB1561023A (en) * | 1977-04-22 | 1980-02-13 | Beecham Group Ltd | 2-methoxy - 5 - chloro aniline derivatives |
| FR2446274A1 (fr) * | 1979-01-15 | 1980-08-08 | Delalande Sa | Nouveaux derives de salicylamide, leur procede de preparation et leur application en therapeutique |
| EP0343307A1 (en) * | 1988-05-26 | 1989-11-29 | Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. | 4-Piperidinealkanamine derivatives |
| FR2674849B1 (fr) * | 1991-04-02 | 1994-12-23 | Logeais Labor Jacques | Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique. |
| FR2766484B1 (fr) * | 1997-07-25 | 1999-09-17 | Logeais Labor Jacques | Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse |
| FR2766486B1 (fr) * | 1997-07-25 | 1999-09-17 | Logeais Labor Jacques | Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse |
| WO2006128803A1 (en) * | 2005-06-02 | 2006-12-07 | F. Hoffmann-La Roche Ag | Piperidin-4-yl-amide derivatives and their use as sst receptor subtype 5 antagonists |
| KR100976063B1 (ko) * | 2007-03-16 | 2010-08-17 | 동아제약주식회사 | 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법 |
| JP6145109B2 (ja) * | 2011-11-29 | 2017-07-05 | ビボゾン インコーポレイテッド | 新規のベンズアミド誘導体、及びこの用途 |
-
1975
- 1975-03-17 AR AR257994A patent/AR216043A1/es active
- 1975-03-18 ES ES435757A patent/ES435757A1/es not_active Expired
- 1975-03-18 ES ES435754A patent/ES435754A1/es not_active Expired
- 1975-03-18 ES ES435756A patent/ES435756A1/es not_active Expired
- 1975-03-18 ES ES435753A patent/ES435753A1/es not_active Expired
- 1975-03-18 ES ES435755A patent/ES435755A1/es not_active Expired
- 1975-03-20 FI FI750825A patent/FI60200C/fi not_active IP Right Cessation
- 1975-03-20 FR FR7509371A patent/FR2264530A1/fr active Granted
- 1975-03-20 NO NO750957A patent/NO144108C/no unknown
- 1975-03-20 DK DK117675A patent/DK147854C/da not_active IP Right Cessation
- 1975-03-20 SE SE7503196A patent/SE427750B/xx not_active IP Right Cessation
- 1975-03-20 CH CH355075A patent/CH602641A5/xx not_active IP Right Cessation
- 1975-03-21 NL NL7503417.A patent/NL159660B/xx not_active IP Right Cessation
- 1975-03-22 JP JP7534871A patent/JPS584019B2/ja not_active Expired
-
1978
- 1978-11-14 KE KE2900A patent/KE2900A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS50129573A (OSRAM) | 1975-10-13 |
| NL159660B (nl) | 1979-03-15 |
| AR216043A1 (es) | 1979-11-30 |
| FI60200C (fi) | 1981-12-10 |
| DK147854C (da) | 1985-07-22 |
| FI750825A7 (OSRAM) | 1975-09-22 |
| NL7503417A (nl) | 1975-09-23 |
| KE2900A (en) | 1978-12-01 |
| ES435756A1 (es) | 1977-04-01 |
| JPS584019B2 (ja) | 1983-01-24 |
| DK147854B (da) | 1984-12-24 |
| NO144108B (no) | 1981-03-16 |
| DK117675A (OSRAM) | 1975-09-22 |
| SE427750B (sv) | 1983-05-02 |
| FI60200B (fi) | 1981-08-31 |
| NO144108C (no) | 1981-06-24 |
| FR2264530A1 (en) | 1975-10-17 |
| FR2264530B1 (OSRAM) | 1978-11-10 |
| NO750957L (OSRAM) | 1975-09-23 |
| SE7503196L (OSRAM) | 1975-09-22 |
| ES435755A1 (es) | 1977-04-01 |
| CH602641A5 (OSRAM) | 1978-07-31 |
| ES435753A1 (es) | 1977-04-01 |
| ES435754A1 (es) | 1977-04-01 |
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