ES435274A1 - Procedimiento de preparacion de n-(2-pirrolidinilalcohil)- benzamidas sustituidas. - Google Patents
Procedimiento de preparacion de n-(2-pirrolidinilalcohil)- benzamidas sustituidas.Info
- Publication number
- ES435274A1 ES435274A1 ES435274A ES435274A ES435274A1 ES 435274 A1 ES435274 A1 ES 435274A1 ES 435274 A ES435274 A ES 435274A ES 435274 A ES435274 A ES 435274A ES 435274 A1 ES435274 A1 ES 435274A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- hydrogen atom
- alcohol
- formula
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940054066 benzamide antipsychotics Drugs 0.000 title abstract 3
- 150000003936 benzamides Chemical class 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- -1 2-pyrrolidinyl alcohol Chemical compound 0.000 abstract 3
- 125000003158 alcohol group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000004466 alkoxycarbonylamino group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000000440 benzylamino group Chemical group [H]N(*)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7407535A FR2262966A1 (fr) | 1974-03-05 | 1974-03-05 | Nouveau benzamide hétérocyclique et son procédé de fabrication |
| FR7503800A FR2299863B1 (fr) | 1975-02-07 | 1975-02-07 | Nouveaux N-(Z-pyrrolidiny alkyl) benzamides substitués, leurs dérivés et leur procédé de préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES435274A1 true ES435274A1 (es) | 1976-12-16 |
Family
ID=26218210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435274A Expired ES435274A1 (es) | 1974-03-05 | 1975-03-04 | Procedimiento de preparacion de n-(2-pirrolidinilalcohil)- benzamidas sustituidas. |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS6015616B2 (is") |
| AR (1) | AR206621A1 (is") |
| AT (1) | AT358570B (is") |
| BG (1) | BG24666A3 (is") |
| CA (1) | CA1047504A (is") |
| CH (1) | CH605794A5 (is") |
| CS (1) | CS189692B2 (is") |
| DD (1) | DD119420A5 (is") |
| DE (1) | DE2507989A1 (is") |
| DK (1) | DK145377C (is") |
| EG (1) | EG12577A (is") |
| ES (1) | ES435274A1 (is") |
| FI (1) | FI750620A7 (is") |
| GB (1) | GB1466822A (is") |
| HK (1) | HK14078A (is") |
| HU (1) | HU170637B (is") |
| IE (1) | IE40818B1 (is") |
| IL (1) | IL46696A (is") |
| LU (1) | LU71949A1 (is") |
| NL (1) | NL7502608A (is") |
| NO (1) | NO750713L (is") |
| OA (1) | OA04966A (is") |
| PH (1) | PH14197A (is") |
| PL (1) | PL97091B1 (is") |
| RO (2) | RO72844A (is") |
| SE (1) | SE411754B (is") |
| SU (1) | SU609464A3 (is") |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ186175A (en) * | 1977-01-27 | 1980-03-05 | Shionogi & Co | Meta-sulphonamidobenzamide derivatives |
| SE8503054D0 (sv) * | 1985-06-19 | 1985-06-19 | Astra Laekemedel Ab | Catecholcarboxamides |
| US4772459A (en) * | 1986-09-09 | 1988-09-20 | Erbamont, Inc. | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein |
| EP0314483A1 (en) * | 1987-10-29 | 1989-05-03 | Erbamont, Inc. | Preparation of benzamides |
| FR2699533A1 (fr) * | 1992-12-21 | 1994-06-24 | Mouhtaram Mohamed | Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3078497A (en) * | 1960-12-29 | 1963-02-26 | Leeds And Mieallef | Dispensing containers |
-
1975
- 1975-02-24 IL IL46696A patent/IL46696A/en unknown
- 1975-02-25 DE DE19752507989 patent/DE2507989A1/de not_active Withdrawn
- 1975-02-26 GB GB809575A patent/GB1466822A/en not_active Expired
- 1975-03-03 AT AT160775A patent/AT358570B/de not_active IP Right Cessation
- 1975-03-03 EG EG109/75A patent/EG12577A/ar active
- 1975-03-03 SE SE7502342A patent/SE411754B/sv not_active IP Right Cessation
- 1975-03-03 LU LU71949A patent/LU71949A1/fr unknown
- 1975-03-04 ES ES435274A patent/ES435274A1/es not_active Expired
- 1975-03-04 CS CS751445A patent/CS189692B2/cs unknown
- 1975-03-04 BG BG029148A patent/BG24666A3/bg unknown
- 1975-03-04 OA OA55430A patent/OA04966A/fr unknown
- 1975-03-04 DK DK86975A patent/DK145377C/da active
- 1975-03-04 FI FI750620A patent/FI750620A7/fi not_active Application Discontinuation
- 1975-03-04 IE IE457/75A patent/IE40818B1/en unknown
- 1975-03-04 HU HUSO1137A patent/HU170637B/hu not_active IP Right Cessation
- 1975-03-04 CA CA221,240A patent/CA1047504A/en not_active Expired
- 1975-03-04 SU SU2112487A patent/SU609464A3/ru active
- 1975-03-04 NO NO750713A patent/NO750713L/no unknown
- 1975-03-05 CH CH279975A patent/CH605794A5/fr not_active IP Right Cessation
- 1975-03-05 RO RO7581558A patent/RO72844A/ro unknown
- 1975-03-05 JP JP50027573A patent/JPS6015616B2/ja not_active Expired
- 1975-03-05 NL NL7502608A patent/NL7502608A/nl not_active Application Discontinuation
- 1975-03-05 RO RO7588831A patent/RO70647A/ro unknown
- 1975-03-05 DD DD184579A patent/DD119420A5/de unknown
- 1975-03-05 PL PL1975178533A patent/PL97091B1/pl unknown
- 1975-04-04 AR AR257837A patent/AR206621A1/es active
-
1977
- 1977-08-22 PH PH20152A patent/PH14197A/en unknown
-
1978
- 1978-03-16 HK HK140/78A patent/HK14078A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK14078A (en) | 1978-03-23 |
| IL46696A (en) | 1978-07-31 |
| DK145377C (da) | 1983-04-11 |
| AT358570B (de) | 1980-09-25 |
| SE7502342L (sv) | 1975-09-08 |
| DD119420A5 (is") | 1976-04-20 |
| LU71949A1 (fr) | 1976-02-04 |
| PL97091B1 (pl) | 1978-02-28 |
| CS189692B2 (en) | 1979-04-30 |
| DE2507989A1 (de) | 1975-09-11 |
| SU609464A1 (ru) | 1978-05-30 |
| JPS50123668A (is") | 1975-09-29 |
| HU170637B (is") | 1977-07-28 |
| NO750713L (is") | 1975-09-08 |
| NL7502608A (nl) | 1975-09-09 |
| SE411754B (sv) | 1980-02-04 |
| BG24666A3 (bg) | 1978-04-12 |
| OA04966A (fr) | 1980-10-31 |
| AR206621A1 (es) | 1976-08-06 |
| DK86975A (da) | 1975-11-03 |
| IL46696A0 (en) | 1975-04-25 |
| EG12577A (en) | 1979-09-30 |
| DK145377B (da) | 1982-11-08 |
| GB1466822A (en) | 1977-03-09 |
| JPS6015616B2 (ja) | 1985-04-20 |
| IE40818L (en) | 1975-09-05 |
| PH14197A (en) | 1981-03-26 |
| RO70647A (ro) | 1980-04-15 |
| IE40818B1 (en) | 1979-08-29 |
| SU609464A3 (ru) | 1978-05-30 |
| FI750620A7 (is") | 1975-09-06 |
| AU7874075A (en) | 1976-09-09 |
| CH605794A5 (fr) | 1978-10-13 |
| ATA160775A (de) | 1980-02-15 |
| RO72844A (ro) | 1981-09-24 |
| CA1047504A (en) | 1979-01-30 |
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