ES434961A1 - Estriol derivatives - Google Patents

Estriol derivatives

Info

Publication number
ES434961A1
ES434961A1 ES434961A ES434961A ES434961A1 ES 434961 A1 ES434961 A1 ES 434961A1 ES 434961 A ES434961 A ES 434961A ES 434961 A ES434961 A ES 434961A ES 434961 A1 ES434961 A1 ES 434961A1
Authority
ES
Spain
Prior art keywords
substitution
estriol
nicotic
etherification
chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES434961A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Theramex SAM
Original Assignee
Laboratoire Theramex SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM
Publication of ES434961A1 publication Critical patent/ES434961A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"PROCEDURE FOR THE PREPARATION OF NEW NICOTINE DERIVATIVES OF ESTRIOL FROM MODULATED HYPOLIPIDEMIANT AND ESTROGEN ACTIVITIES", characterized in that, starting from estriol and in the case that the substitution in position C (3) is an etherification, it proceeds first. to said etherification, then to the substitution of the remaining hydroxyls in positions 16α and 17β by acylation with the nicotic chloride or the N-oxide of the nicotic chloride, and, in the event that the substitution in position is an esterification, proceed directly to the substitution of the hydroxyls in position C (3) 16 and 17, then, eventually, to selectively hydrolyze the ester function in C (3), and to proceed to a new acylation in C (3) by a different acyl residue. (Machine-translation by Google Translate, not legally binding)
ES434961A 1974-02-26 1975-02-21 Estriol derivatives Expired ES434961A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB871274A GB1452794A (en) 1974-02-26 1974-02-26 Estriol derivatives

Publications (1)

Publication Number Publication Date
ES434961A1 true ES434961A1 (en) 1976-12-16

Family

ID=9857798

Family Applications (1)

Application Number Title Priority Date Filing Date
ES434961A Expired ES434961A1 (en) 1974-02-26 1975-02-21 Estriol derivatives

Country Status (14)

Country Link
JP (1) JPS5842199B2 (en)
AR (1) AR206704A1 (en)
BE (1) BE826016A (en)
BR (1) BR7501131A (en)
CA (1) CA1062699A (en)
CH (1) CH614218A5 (en)
ES (1) ES434961A1 (en)
FR (1) FR2261775B1 (en)
GB (1) GB1452794A (en)
IE (1) IE40689B1 (en)
IT (1) IT1048803B (en)
LU (1) LU71909A1 (en)
NL (1) NL180108C (en)
SE (1) SE419091B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60258198A (en) * 1984-06-04 1985-12-20 Amano Pharmaceut Co Ltd Triterpene alcohol organic acid ester and its preparation

Also Published As

Publication number Publication date
NL180108B (en) 1986-08-01
IT1048803B (en) 1980-12-20
FR2261775B1 (en) 1980-05-16
GB1452794A (en) 1976-10-13
AR206704A1 (en) 1976-08-13
IE40689L (en) 1975-08-26
IE40689B1 (en) 1979-08-01
SE7502107L (en) 1975-08-27
FR2261775A1 (en) 1975-09-19
CA1062699A (en) 1979-09-18
NL7502299A (en) 1975-08-28
JPS50142555A (en) 1975-11-17
SE419091B (en) 1981-07-13
LU71909A1 (en) 1975-08-20
BR7501131A (en) 1975-12-02
BE826016A (en) 1975-06-16
CH614218A5 (en) 1979-11-15
JPS5842199B2 (en) 1983-09-17
NL180108C (en) 1987-01-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001