ES428107A1 - Un procedimiento para la preparacion de un compuesto de pi-perazinilquinoxalinas. - Google Patents
Un procedimiento para la preparacion de un compuesto de pi-perazinilquinoxalinas.Info
- Publication number
- ES428107A1 ES428107A1 ES428107A ES428107A ES428107A1 ES 428107 A1 ES428107 A1 ES 428107A1 ES 428107 A ES428107 A ES 428107A ES 428107 A ES428107 A ES 428107A ES 428107 A1 ES428107 A1 ES 428107A1
- Authority
- ES
- Spain
- Prior art keywords
- carbalkoxy
- hydrogen
- alkanoyl
- aryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RELPOLSGTUYMFR-UHFFFAOYSA-N 2-piperazin-1-ylquinoxaline Chemical class C1CNCCN1C1=CN=C(C=CC=C2)C2=N1 RELPOLSGTUYMFR-UHFFFAOYSA-N 0.000 title abstract 2
- 239000001257 hydrogen Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- -1 carbalkoxy Chemical group 0.000 abstract 4
- 125000001589 carboacyl group Chemical group 0.000 abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract 4
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 125000003107 substituted aryl group Chemical group 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229930194542 Keto Chemical group 0.000 abstract 2
- 125000005118 N-alkylcarbamoyl group Chemical group 0.000 abstract 2
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000003435 aroyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000468 ketone group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- XSCHRSMBECNVNS-UHFFFAOYSA-N quinoxaline Chemical compound N1=CC=NC2=CC=CC=C21 XSCHRSMBECNVNS-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005277 alkyl imino group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 125000005098 aryl alkoxy carbonyl group Chemical group 0.000 abstract 1
- 125000005161 aryl oxy carbonyl group Chemical group 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 abstract 1
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 abstract 1
- 125000004995 haloalkylthio group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003252 quinoxalines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37902273A | 1973-07-13 | 1973-07-13 | |
| US46538174A | 1974-04-29 | 1974-04-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES428107A1 true ES428107A1 (es) | 1976-11-16 |
Family
ID=27008442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES428107A Expired ES428107A1 (es) | 1973-07-13 | 1974-07-09 | Un procedimiento para la preparacion de un compuesto de pi-perazinilquinoxalinas. |
Country Status (18)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091098A (en) * | 1977-04-25 | 1978-05-23 | Merck & Co., Inc. | 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides |
| US4082845A (en) * | 1977-04-25 | 1978-04-04 | Merck & Co., Inc. | 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines |
| US4107309A (en) * | 1977-05-23 | 1978-08-15 | American Cyanamid Company | Substituted imidazo[1,2-d]-as-triazines |
| US4091101A (en) * | 1977-06-15 | 1978-05-23 | Merck & Co., Inc. | 6-(1-Piperazinyl)quinoxaline |
| EP0094498A3 (en) * | 1982-05-06 | 1985-04-03 | American Cyanamid Company | Antiatherosclerotic 1-piperazine derivatives |
| ES2042395B1 (es) * | 1992-02-27 | 1994-06-16 | Promotora Catalana De Inversio | Procedimiento para la obtencion de derivados de 2-ciano-3-piperacinilquinoxalinas. |
| FR2731221B1 (fr) * | 1995-03-01 | 1997-05-30 | Pf Medicament | Nouveaux derives de l'ethyl-1 dihydro-1, 2 oxo-2 methylamino-3 quinoxaline, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant |
| AU9810498A (en) * | 1997-10-24 | 1999-05-17 | Neurogen Corporation | 1-(2-naphthyl) and 1-(2-azanaphthyl)-4 -(1-phenylmethyl)piperazines being dopamine d4 receptor subtyp e ligands |
| US6040448A (en) | 1997-10-24 | 2000-03-21 | Neurogen Corporation | Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands |
| WO2000012500A2 (en) * | 1998-09-02 | 2000-03-09 | Neurogen Corporation | 2-aryl-4-(1-[4-heteroaryl]piperazin-1-yl) methylimidazoles: dopamine d4 receptor subtype ligands |
| SE9901884D0 (sv) * | 1999-05-21 | 1999-05-21 | Pharmacia & Upjohn Ab | Novel compounds their use and preparation |
| ES2252004T3 (es) * | 1999-05-21 | 2006-05-16 | Biovitrum Ab | Nuevos compuestos, su uso y preparacion. |
| US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| JP4707261B2 (ja) * | 2001-05-15 | 2011-06-22 | 日本エンバイロケミカルズ株式会社 | キノキサリン系化合物および工業用殺菌組成物 |
| NZ536664A (en) | 2002-06-19 | 2007-07-27 | Biovitrum Ab | Piperazinylpyrazine derivative compounds, their use and preparation |
| CA2492924C (en) * | 2002-07-19 | 2011-12-20 | Biovitrum Ab | Novel piperazinone derivates for the treatment of 5-ht2a receptor-related disorders |
| SE0202287D0 (sv) * | 2002-07-19 | 2002-07-19 | Biovitrum Ab | New compounds |
| CA2517291C (en) * | 2003-03-19 | 2012-05-08 | Exelixis, Inc. | Ortho-substituted aryl and heteroaryl tie-2 modulators and methods of use |
| MXPA06003578A (es) * | 2003-09-30 | 2006-08-31 | Johnson & Johnson | Compuestos de quinoxalina. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL260335A (enrdf_load_stackoverflow) * | 1960-01-22 | |||
| CH450434A (de) * | 1961-12-14 | 1968-01-31 | Ciba Geigy | Verfahren zur Herstellung von Diazinen |
| BE788451A (fr) * | 1971-09-08 | 1973-03-06 | Bayer Ag | Nouvelles 2-amino-quinoxalines, leur procede de preparation et leur application comme insecticides, acaricides et fongicides |
| GB1457400A (en) * | 1972-11-20 | 1976-12-01 | Pfizer | Pharmaceutical compositions containing 2-substituted quinoxa lines |
-
1974
- 1974-06-25 FI FI1939/74A patent/FI193974A7/fi unknown
- 1974-06-26 DK DK342674A patent/DK342674A/da unknown
- 1974-06-27 SE SE7408486A patent/SE417316B/xx unknown
- 1974-06-27 NL NL7408705A patent/NL7408705A/xx not_active Application Discontinuation
- 1974-06-27 NO NO742351A patent/NO742351L/no unknown
- 1974-07-01 IL IL45158A patent/IL45158A0/xx unknown
- 1974-07-02 IE IE1397/74A patent/IE39869B1/xx unknown
- 1974-07-02 AU AU70731/74A patent/AU7073174A/en not_active Expired
- 1974-07-08 GB GB3017674A patent/GB1440722A/en not_active Expired
- 1974-07-09 ES ES428107A patent/ES428107A1/es not_active Expired
- 1974-07-11 LU LU70510A patent/LU70510A1/xx unknown
- 1974-07-11 DE DE2433397A patent/DE2433397A1/de active Pending
- 1974-07-11 DD DD179871A patent/DD112127A5/xx unknown
- 1974-07-11 FR FR7424114A patent/FR2236499B1/fr not_active Expired
- 1974-07-12 CH CH964874A patent/CH605919A5/xx not_active IP Right Cessation
- 1974-07-13 RO RO7400079481A patent/RO63539A/ro unknown
- 1974-07-13 JP JP49079774A patent/JPS5037791A/ja active Pending
- 1974-07-13 BG BG027222A patent/BG21606A3/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LU70510A1 (enrdf_load_stackoverflow) | 1975-03-27 |
| IE39869B1 (en) | 1979-01-17 |
| JPS5037791A (enrdf_load_stackoverflow) | 1975-04-08 |
| FI193974A7 (enrdf_load_stackoverflow) | 1975-01-14 |
| DK342674A (enrdf_load_stackoverflow) | 1975-03-03 |
| DE2433397A1 (de) | 1975-02-06 |
| IE39869L (en) | 1975-01-13 |
| IL45158A0 (en) | 1974-11-29 |
| DD112127A5 (enrdf_load_stackoverflow) | 1975-03-20 |
| NL7408705A (nl) | 1975-01-15 |
| BG21606A3 (bg) | 1976-07-20 |
| RO63539A (fr) | 1978-07-15 |
| SE7408486L (sv) | 1975-01-14 |
| NO742351L (enrdf_load_stackoverflow) | 1975-02-10 |
| FR2236499A1 (enrdf_load_stackoverflow) | 1975-02-07 |
| AU7073174A (en) | 1976-01-08 |
| FR2236499B1 (enrdf_load_stackoverflow) | 1977-04-15 |
| SE417316B (sv) | 1981-03-09 |
| CH605919A5 (enrdf_load_stackoverflow) | 1978-10-13 |
| GB1440722A (en) | 1976-06-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES428107A1 (es) | Un procedimiento para la preparacion de un compuesto de pi-perazinilquinoxalinas. | |
| EP0371731A3 (en) | Quinazolinone derivatives | |
| ES480542A1 (es) | Metodo para producir derivados de imidazol. | |
| HUT42428A (en) | Process for preparing naphthalene derivatives | |
| GB1313689A (en) | Quinoxaline derivatives | |
| ES468173A1 (es) | Un procedimiento para la preparacion de derivados de morfina | |
| GB1374283A (en) | Benzothiazine benzoxazine and indoline derivatives | |
| GB1237008A (en) | Novel indoline derivatives | |
| ES8400440A1 (es) | "procedimiento para preparar nuevas triazoloquinazolonas". | |
| ES468170A1 (es) | Un procedimiento para la preparacion de un nuevo derivado demorfina | |
| ES8104269A1 (es) | Procedimiento para la preparacion de nuevos derivados de 3-amino-1-benzoxepina | |
| ES8401926A1 (es) | Un procedimiento para la preparacion de un compuesto de hidroxibencilaminobenceno, dotado de propiedades antiinflamatorias. | |
| ES8107212A1 (es) | Procedimiento para la preparacion de derivados de 3-amino-1-benzoxepin-5(2h)-ona | |
| ES8703861A1 (es) | Un procedimiento para preparar nuevas 1,2,4-tiadiazinas | |
| GB1254270A (en) | Benzoxazepine derivatives | |
| ES8200339A1 (es) | Metodo de preparar compuestos de la serie de las beta-lacta-mas y similares | |
| HU894471D0 (en) | Process for the preparation of 15-amino-20,21-dinor-eburnamenine derivatives and pharmaceutical compositions containing them | |
| GB1443863A (en) | Aminoethanol derivatives | |
| ES8307250A1 (es) | Un procedimiento para la preparacion de nuevos derivados de ciclohepta (1,2-b) pirrol. | |
| GB1291012A (enrdf_load_stackoverflow) |