ES426998A1 - Procedimiento para la obtencion de aminoglicosidos de 2 - deoxi - estreptamina. - Google Patents

Procedimiento para la obtencion de aminoglicosidos de 2 - deoxi - estreptamina.

Info

Publication number
ES426998A1
ES426998A1 ES426998A ES426998A ES426998A1 ES 426998 A1 ES426998 A1 ES 426998A1 ES 426998 A ES426998 A ES 426998A ES 426998 A ES426998 A ES 426998A ES 426998 A1 ES426998 A1 ES 426998A1
Authority
ES
Spain
Prior art keywords
aminoglycoside antibiotics
intermediates therefor
aminoglycoside
novel derivatives
dehydrokanamycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES426998A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2671873A external-priority patent/GB1445871A/en
Priority claimed from GB2671973A external-priority patent/GB1445872A/en
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Publication of ES426998A1 publication Critical patent/ES426998A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES426998A 1973-06-05 1974-06-05 Procedimiento para la obtencion de aminoglicosidos de 2 - deoxi - estreptamina. Expired ES426998A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2671873A GB1445871A (en) 1973-06-05 1973-06-05 Intermediates for the preparation of 2-deoxystreptamine-amino glycosides
GB2671973A GB1445872A (en) 1973-06-05 1973-06-05 2-deoxystreptamine-aminoglycosides and methods for their preparation paration

Publications (1)

Publication Number Publication Date
ES426998A1 true ES426998A1 (es) 1976-09-01

Family

ID=26258384

Family Applications (1)

Application Number Title Priority Date Filing Date
ES426998A Expired ES426998A1 (es) 1973-06-05 1974-06-05 Procedimiento para la obtencion de aminoglicosidos de 2 - deoxi - estreptamina.

Country Status (8)

Country Link
US (1) US4024332A (enExample)
JP (1) JPS5035131A (enExample)
DE (1) DE2427096A1 (enExample)
DK (1) DK304574A (enExample)
ES (1) ES426998A1 (enExample)
FR (1) FR2232326B1 (enExample)
LU (1) LU70223A1 (enExample)
NL (1) NL7407483A (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2712160A1 (de) * 1977-03-19 1978-09-28 Bayer Ag Pseudotrisaccharide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2730372A1 (de) * 1977-07-05 1979-01-25 Bayer Ag Pseudodisaccharide
JPS6030320B2 (ja) * 1978-01-13 1985-07-16 山之内製薬株式会社 新規抗生物質およびその製造法
FR2427341A1 (fr) * 1978-06-02 1979-12-28 Delalande Sa Nouveaux derives aminoglycosidiques hemisynthetiques, leur procede de preparation et leur application en therapeutique
US4247687A (en) * 1979-06-12 1981-01-27 Farmitalia Carlo Erba S.P.A. Aminoglycoside antibiotic derivatives and process for their preparation
US4831123A (en) * 1985-10-15 1989-05-16 Schering Corporation Process for preparing netilmicin
DE4137271A1 (de) * 1991-11-13 1993-05-19 Bayer Ag Verfahren zur herstellung von n-(2-chlor-pyridin-5-yl-methyl)-ethylendiamin
DE4429465A1 (de) 1994-08-19 1996-02-22 Bayer Ag Verfahren zur Herstellung von 2-Halogenpyridinaldehyden und neue 2-Halogenpyridinaldehyde
AU2002953095A0 (en) * 2002-11-29 2002-12-19 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
HUE031643T2 (en) * 2006-04-03 2017-07-28 Technion Res & Dev Foundation New aminoglycosides and their applications in the treatment of genetic disorders
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
US10786520B2 (en) 2015-09-02 2020-09-29 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
CN114957357A (zh) 2015-09-02 2022-08-30 Eloxx制药有限公司 氨基糖苷衍生物及其在治疗遗传性病症中的应用
EP3344640A4 (en) 2015-09-02 2019-05-01 Eloxx Pharmaceuticals Ltd. AMINO-LIKES DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF GENETIC DISEASES
BR112019018834A2 (pt) 2017-03-15 2020-04-14 Eloxx Pharmaceuticals Ltd preparação em grande escala de aminoglicosídeos de pseudotrissacarídeos e de seus intermediários
WO2020105054A1 (en) 2018-11-22 2020-05-28 Technion Research & Development Foundation Limited Modified aminoglycoside compounds and uses thereof in disabling bacterial ribosome
US12110310B2 (en) * 2020-01-23 2024-10-08 Utah State University Amphiphilic kanamycin compositions and methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE630462A (enExample) * 1962-04-03

Also Published As

Publication number Publication date
DK304574A (enExample) 1975-02-03
DE2427096A1 (de) 1975-01-09
FR2232326B1 (enExample) 1977-11-10
NL7407483A (enExample) 1974-12-09
LU70223A1 (enExample) 1976-04-13
JPS5035131A (enExample) 1975-04-03
FR2232326A1 (enExample) 1975-01-03
US4024332A (en) 1977-05-17

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