JPS5035131A - - Google Patents

Info

Publication number
JPS5035131A
JPS5035131A JP49063829A JP6382974A JPS5035131A JP S5035131 A JPS5035131 A JP S5035131A JP 49063829 A JP49063829 A JP 49063829A JP 6382974 A JP6382974 A JP 6382974A JP S5035131 A JPS5035131 A JP S5035131A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP49063829A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2671973A external-priority patent/GB1445872A/en
Priority claimed from GB2671873A external-priority patent/GB1445871A/en
Application filed filed Critical
Publication of JPS5035131A publication Critical patent/JPS5035131A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP49063829A 1973-06-05 1974-06-05 Pending JPS5035131A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2671973A GB1445872A (en) 1973-06-05 1973-06-05 2-deoxystreptamine-aminoglycosides and methods for their preparation paration
GB2671873A GB1445871A (en) 1973-06-05 1973-06-05 Intermediates for the preparation of 2-deoxystreptamine-amino glycosides

Publications (1)

Publication Number Publication Date
JPS5035131A true JPS5035131A (ja) 1975-04-03

Family

ID=26258384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49063829A Pending JPS5035131A (ja) 1973-06-05 1974-06-05

Country Status (8)

Country Link
US (1) US4024332A (ja)
JP (1) JPS5035131A (ja)
DE (1) DE2427096A1 (ja)
DK (1) DK304574A (ja)
ES (1) ES426998A1 (ja)
FR (1) FR2232326B1 (ja)
LU (1) LU70223A1 (ja)
NL (1) NL7407483A (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2712160A1 (de) * 1977-03-19 1978-09-28 Bayer Ag Pseudotrisaccharide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2730372A1 (de) * 1977-07-05 1979-01-25 Bayer Ag Pseudodisaccharide
JPS6030320B2 (ja) * 1978-01-13 1985-07-16 山之内製薬株式会社 新規抗生物質およびその製造法
FR2427341A1 (fr) * 1978-06-02 1979-12-28 Delalande Sa Nouveaux derives aminoglycosidiques hemisynthetiques, leur procede de preparation et leur application en therapeutique
US4247687A (en) * 1979-06-12 1981-01-27 Farmitalia Carlo Erba S.P.A. Aminoglycoside antibiotic derivatives and process for their preparation
US4831123A (en) * 1985-10-15 1989-05-16 Schering Corporation Process for preparing netilmicin
DE4137271A1 (de) * 1991-11-13 1993-05-19 Bayer Ag Verfahren zur herstellung von n-(2-chlor-pyridin-5-yl-methyl)-ethylendiamin
DE4429465A1 (de) 1994-08-19 1996-02-22 Bayer Ag Verfahren zur Herstellung von 2-Halogenpyridinaldehyden und neue 2-Halogenpyridinaldehyde
AU2002953095A0 (en) * 2002-11-29 2002-12-19 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
EP2007783B1 (en) 2006-04-03 2018-07-11 Technion Research & Development Foundation Ltd. Novel aminoglycosides and uses thereof in the treatment of genetic disorders
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
US10786520B2 (en) 2015-09-02 2020-09-29 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
US11306115B2 (en) 2015-09-02 2022-04-19 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
IL257820B (en) 2015-09-02 2022-09-01 Eloxx Pharmaceuticals Ltd Aminoglycosides for the treatment of genetic diseases
US11136345B2 (en) 2017-03-15 2021-10-05 Eloxx Pharmaceuticals Ltd. Large scale preparation of pseudo-trisaccharide aminoglycosides and of intermediates thereof
WO2020105054A1 (en) 2018-11-22 2020-05-28 Technion Research & Development Foundation Limited Modified aminoglycoside compounds and uses thereof in disabling bacterial ribosome
US20210230203A1 (en) * 2020-01-23 2021-07-29 Utah State University Amphiphilic Kanamycin Compositions and Methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL291070A (ja) * 1962-04-03

Also Published As

Publication number Publication date
DE2427096A1 (de) 1975-01-09
LU70223A1 (ja) 1976-04-13
FR2232326A1 (ja) 1975-01-03
NL7407483A (ja) 1974-12-09
ES426998A1 (es) 1976-09-01
FR2232326B1 (ja) 1977-11-10
US4024332A (en) 1977-05-17
DK304574A (ja) 1975-02-03

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