ES426505A1 - Un procedimiento para la preparacion de compuestos aneste- sicos locales de alcohilo terciario-amino-acilo inferior-xi-lidida. - Google Patents
Un procedimiento para la preparacion de compuestos aneste- sicos locales de alcohilo terciario-amino-acilo inferior-xi-lidida.Info
- Publication number
- ES426505A1 ES426505A1 ES426505A ES426505A ES426505A1 ES 426505 A1 ES426505 A1 ES 426505A1 ES 426505 A ES426505 A ES 426505A ES 426505 A ES426505 A ES 426505A ES 426505 A1 ES426505 A1 ES 426505A1
- Authority
- ES
- Spain
- Prior art keywords
- local anesthetic
- formula
- xylidide
- lidocaine
- xilocaine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Compuestos anestésicos locales de alcohilo terciaro-amino-acilo-inferior-xilidida. Los dos compuestos anestésicos locales de acilixilidida que están disponibles en el comercion son la N-n-butilpipecolil-2,6-xilidida o bupivacaína vendido con la marca registrada "Marcaina" que tiene la fórmula estructura **fórmula** y la dietilaminoaceto-2,6-xilidida u omega-dietilamino-2,6-dimetil-acetanilida o lidocaína vendida con la marca registrada "Xilocaina que tiene la fórmula estructural **fórmula** Sin embargo, aunque la buvivacaina o "Marcaina" es un anestésico local de larga duración, tiene el inconveniente de ser más irritante para los tejidos que la lidocaina y aunque la lidocaina o "Xilocaina" no es irritante para los tejidos, tiene el inconveniente de no ser un anestésico local de larga duración.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23011472A | 1972-02-28 | 1972-02-28 | |
| US32537873A | 1973-01-22 | 1973-01-22 | |
| AT587374A AT326641B (de) | 1972-02-28 | 1973-02-26 | Verfahren zur herstellung von neuen n,n-dialkylaminoessigsaure-2,6-xylididen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES426505A1 true ES426505A1 (es) | 1976-12-01 |
Family
ID=30773186
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES73412068A Expired ES412068A1 (es) | 1972-02-28 | 1973-02-26 | Un procedimiento para la preparacion de compuestos anaste- sicos locales. |
| ES426505A Expired ES426505A1 (es) | 1972-02-28 | 1974-05-21 | Un procedimiento para la preparacion de compuestos aneste- sicos locales de alcohilo terciario-amino-acilo inferior-xi-lidida. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES73412068A Expired ES412068A1 (es) | 1972-02-28 | 1973-02-26 | Un procedimiento para la preparacion de compuestos anaste- sicos locales. |
Country Status (10)
| Country | Link |
|---|---|
| JP (2) | JPS4897822A (es) |
| AR (2) | AR200995A1 (es) |
| AT (1) | AT326110B (es) |
| CH (2) | CH589046A5 (es) |
| ES (2) | ES412068A1 (es) |
| FR (1) | FR2181766B1 (es) |
| GB (2) | GB1423762A (es) |
| IE (1) | IE37932B1 (es) |
| NL (2) | NL7302541A (es) |
| NO (2) | NO137501B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5834693A (ja) * | 1981-08-26 | 1983-03-01 | Hitachi Ltd | コンバ−ゼンス補正装置 |
| JPS5848589A (ja) * | 1981-09-18 | 1983-03-22 | Hitachi Ltd | コンバ−ゼンス補正装置 |
| ZA828142B (en) * | 1981-11-16 | 1984-06-27 | Dow Chemical Co | Inhibiting the antagonism between pyridyloxy-phenoxyalkanoate herbicides and benzothiadiazinone herbicides in post-emergent applications |
| US4855497A (en) * | 1985-04-02 | 1989-08-08 | Chugai Seiyaku Kabushiki Kaisha | Novel diamine derivatives |
-
1973
- 1973-02-23 NL NL7302541A patent/NL7302541A/xx unknown
- 1973-02-26 GB GB2855475A patent/GB1423762A/en not_active Expired
- 1973-02-26 GB GB939173A patent/GB1423761A/en not_active Expired
- 1973-02-26 ES ES73412068A patent/ES412068A1/es not_active Expired
- 1973-02-26 AT AT167273A patent/AT326110B/de not_active IP Right Cessation
- 1973-02-27 FR FR7306927A patent/FR2181766B1/fr not_active Expired
- 1973-02-27 CH CH1077776A patent/CH589046A5/xx not_active IP Right Cessation
- 1973-02-27 CH CH282873A patent/CH585698A5/xx not_active IP Right Cessation
- 1973-02-27 NO NO79273A patent/NO137501B/no unknown
- 1973-02-27 IE IE30573A patent/IE37932B1/xx unknown
- 1973-02-27 AR AR24681673A patent/AR200995A1/es active
- 1973-02-28 JP JP2417273A patent/JPS4897822A/ja active Pending
- 1973-10-12 NO NO397673A patent/NO137498B/no unknown
-
1974
- 1974-05-21 ES ES426505A patent/ES426505A1/es not_active Expired
- 1974-11-29 AR AR25673274A patent/AR201072A1/es active
-
1975
- 1975-06-23 JP JP7744175A patent/JPS5119733A/ja active Pending
-
1978
- 1978-01-02 NL NL7800008A patent/NL7800008A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES412068A1 (es) | 1976-01-01 |
| DE2309023B2 (de) | 1976-08-19 |
| AR200995A1 (es) | 1975-02-06 |
| NO137498B (no) | 1977-11-28 |
| NO137501B (no) | 1977-11-28 |
| NL7302541A (es) | 1973-08-30 |
| GB1423761A (en) | 1976-02-04 |
| GB1423762A (en) | 1976-02-04 |
| CH589046A5 (es) | 1977-06-30 |
| JPS5119733A (en) | 1976-02-17 |
| IE37932L (en) | 1973-08-28 |
| AU5258373A (en) | 1974-08-29 |
| DE2309023A1 (de) | 1973-09-13 |
| AT326110B (de) | 1975-11-25 |
| NL7800008A (nl) | 1978-05-31 |
| JPS4897822A (es) | 1973-12-13 |
| ATA167273A (de) | 1975-02-15 |
| IE37932B1 (en) | 1977-11-23 |
| FR2181766A1 (es) | 1973-12-07 |
| AR201072A1 (es) | 1975-02-06 |
| CH585698A5 (es) | 1977-03-15 |
| FR2181766B1 (es) | 1976-09-03 |
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