FR2315276A1 - Compositions pharmaceutiques contenant des tetrahydroisoquinoleines substituees - Google Patents

Compositions pharmaceutiques contenant des tetrahydroisoquinoleines substituees

Info

Publication number
FR2315276A1
FR2315276A1 FR7618972A FR7618972A FR2315276A1 FR 2315276 A1 FR2315276 A1 FR 2315276A1 FR 7618972 A FR7618972 A FR 7618972A FR 7618972 A FR7618972 A FR 7618972A FR 2315276 A1 FR2315276 A1 FR 2315276A1
Authority
FR
France
Prior art keywords
tetrahydroisoquinoleins
pharmaceutical compositions
compositions containing
containing substituted
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7618972A
Other languages
English (en)
Other versions
FR2315276B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/590,772 external-priority patent/US3988339A/en
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of FR2315276A1 publication Critical patent/FR2315276A1/fr
Application granted granted Critical
Publication of FR2315276B1 publication Critical patent/FR2315276B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/298Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C07C45/43Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis of >CX2 groups, X being halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FR7618972A 1975-06-26 1976-06-22 Compositions pharmaceutiques contenant des tetrahydroisoquinoleines substituees Granted FR2315276A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/590,772 US3988339A (en) 1974-02-08 1975-06-26 Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase

Publications (2)

Publication Number Publication Date
FR2315276A1 true FR2315276A1 (fr) 1977-01-21
FR2315276B1 FR2315276B1 (fr) 1980-03-14

Family

ID=24363639

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7618972A Granted FR2315276A1 (fr) 1975-06-26 1976-06-22 Compositions pharmaceutiques contenant des tetrahydroisoquinoleines substituees

Country Status (12)

Country Link
US (1) US4062961A (fr)
JP (1) JPS527445A (fr)
AU (1) AU499217B2 (fr)
BE (1) BE843412A (fr)
CA (1) CA1069440A (fr)
DE (1) DE2628425A1 (fr)
FR (1) FR2315276A1 (fr)
GB (1) GB1561583A (fr)
IE (1) IE43794B1 (fr)
IL (1) IL49897A (fr)
NL (1) NL7606960A (fr)
ZA (1) ZA763806B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258049A (en) * 1979-07-02 1981-03-24 Smithkline Corporation Inhibiting phenylethanolamine N-methyltransferase with thiadiazolo and oxadiazolotetrahydroisoquinolines
US4340600A (en) * 1980-05-22 1982-07-20 Smithkline Corporation Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988339A (en) * 1974-02-08 1976-10-26 Smithkline Corporation Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase

Also Published As

Publication number Publication date
AU1532376A (en) 1978-01-05
ZA763806B (en) 1977-05-25
GB1561583A (en) 1980-02-27
US4062961A (en) 1977-12-13
IE43794B1 (en) 1981-06-03
NL7606960A (nl) 1976-12-28
CA1069440A (fr) 1980-01-08
BE843412A (fr) 1976-12-27
FR2315276B1 (fr) 1980-03-14
AU499217B2 (en) 1979-04-12
JPS527445A (en) 1977-01-20
IL49897A0 (en) 1976-08-31
IE43794L (en) 1976-12-26
DE2628425A1 (de) 1977-01-20
IL49897A (en) 1979-09-30

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Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse