ES422155A1 - Un procedimiento para la preparacion de 2,2'-anhidro-1-be- ta-d-arabinofuranosil 5-fluorocitosina. - Google Patents
Un procedimiento para la preparacion de 2,2'-anhidro-1-be- ta-d-arabinofuranosil 5-fluorocitosina.Info
- Publication number
- ES422155A1 ES422155A1 ES422155A ES422155A ES422155A1 ES 422155 A1 ES422155 A1 ES 422155A1 ES 422155 A ES422155 A ES 422155A ES 422155 A ES422155 A ES 422155A ES 422155 A1 ES422155 A1 ES 422155A1
- Authority
- ES
- Spain
- Prior art keywords
- anhydro
- fluorocytosine
- aafc
- arabinofuranosil
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XRECTZIEBJDKEO-UHFFFAOYSA-N flucytosine Chemical compound NC1=NC(=O)NC=C1F XRECTZIEBJDKEO-UHFFFAOYSA-N 0.000 title 1
- 229960004413 flucytosine Drugs 0.000 title 1
- PAYBYKKERMGTSS-MNCSTQPFSA-N (2r,3r,3as,9ar)-7-fluoro-2-(hydroxymethyl)-6-imino-2,3,3a,9a-tetrahydrofuro[1,2][1,3]oxazolo[3,4-a]pyrimidin-3-ol Chemical compound N=C1C(F)=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3OC2=N1 PAYBYKKERMGTSS-MNCSTQPFSA-N 0.000 abstract 3
- RMCFDHVUFKPQRX-CFHSPSGHSA-N (2r,3r,3as,9ar)-7-fluoro-2-(hydroxymethyl)-6-imino-2,3,3a,9a-tetrahydrofuro[1,2][1,3]oxazolo[3,4-a]pyrimidin-3-ol;hydrochloride Chemical compound Cl.N=C1C(F)=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3OC2=N1 RMCFDHVUFKPQRX-CFHSPSGHSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/322,837 US4124757A (en) | 1973-01-11 | 1973-01-11 | Process for preparing 2,2'-anhydro-1β-D-arabi nofuranosyl-5-fluorocytosine and salts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES422155A1 true ES422155A1 (es) | 1976-04-16 |
Family
ID=23256649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES422155A Expired ES422155A1 (es) | 1973-01-11 | 1974-01-10 | Un procedimiento para la preparacion de 2,2'-anhidro-1-be- ta-d-arabinofuranosil 5-fluorocitosina. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4124757A (forum.php) |
| JP (1) | JPS5418266B2 (forum.php) |
| AR (1) | AR201121A1 (forum.php) |
| AT (1) | AT331999B (forum.php) |
| BE (1) | BE809592A (forum.php) |
| CA (1) | CA1008451A (forum.php) |
| CH (1) | CH586718A5 (forum.php) |
| DD (1) | DD109631A5 (forum.php) |
| DE (1) | DE2363536C3 (forum.php) |
| DK (1) | DK133247C (forum.php) |
| ES (1) | ES422155A1 (forum.php) |
| FR (1) | FR2323686A1 (forum.php) |
| GB (1) | GB1407381A (forum.php) |
| HU (1) | HU169851B (forum.php) |
| IE (1) | IE38785B1 (forum.php) |
| IL (1) | IL43619A (forum.php) |
| LU (1) | LU69129A1 (forum.php) |
| NL (1) | NL150804B (forum.php) |
| NO (1) | NO138146C (forum.php) |
| PL (1) | PL88485B1 (forum.php) |
| SE (1) | SE407689B (forum.php) |
| ZA (1) | ZA738658B (forum.php) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5527782A (en) * | 1990-03-13 | 1996-06-18 | Acic (Canada) Inc. | 5-halo-2,3'-O-cyclocytidines |
| US7337777B1 (en) * | 2005-03-29 | 2008-03-04 | Steven Islava | Airway stabilizer for resuscitation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3155646A (en) * | 1960-08-23 | 1964-11-03 | Upjohn Co | 1-arabinofuranosyl-5-halouracil and process for the preparation thereof |
| US3709874A (en) * | 1970-03-19 | 1973-01-09 | Syntex Corp | 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing |
| US3812098A (en) * | 1970-03-19 | 1974-05-21 | Syntex Inc | O2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosine derivatives and methods of making and related procedures |
| DE2310302A1 (de) * | 1972-03-03 | 1973-09-20 | Syntex Corp | 0 hoch 2,2'-anhydro-1-(beta-darabinofuranosyl)-cytosinderivate und verfahren zu ihrer herstellung |
-
1973
- 1973-01-11 CH CH1559873A patent/CH586718A5/xx not_active IP Right Cessation
- 1973-01-11 US US05/322,837 patent/US4124757A/en not_active Expired - Lifetime
- 1973-11-12 ZA ZA738658A patent/ZA738658B/xx unknown
- 1973-11-12 IL IL43619A patent/IL43619A/en unknown
- 1973-11-13 CA CA185,714A patent/CA1008451A/en not_active Expired
- 1973-11-28 NL NL737316269A patent/NL150804B/xx unknown
- 1973-11-30 AR AR251278A patent/AR201121A1/es active
- 1973-12-20 DE DE2363536A patent/DE2363536C3/de not_active Expired
- 1973-12-28 NO NO5007/73A patent/NO138146C/no unknown
-
1974
- 1974-01-07 IE IE27/74A patent/IE38785B1/xx unknown
- 1974-01-09 DD DD175919A patent/DD109631A5/xx unknown
- 1974-01-09 PL PL1974168003A patent/PL88485B1/pl unknown
- 1974-01-09 JP JP540474A patent/JPS5418266B2/ja not_active Expired
- 1974-01-09 LU LU69129A patent/LU69129A1/xx unknown
- 1974-01-09 FR FR7400695A patent/FR2323686A1/fr active Granted
- 1974-01-09 HU HUHO1639A patent/HU169851B/hu unknown
- 1974-01-10 DK DK13774*#A patent/DK133247C/da active
- 1974-01-10 SE SE7400314A patent/SE407689B/xx unknown
- 1974-01-10 AT AT17274*#A patent/AT331999B/de not_active IP Right Cessation
- 1974-01-10 BE BE139682A patent/BE809592A/xx unknown
- 1974-01-10 GB GB114274A patent/GB1407381A/en not_active Expired
- 1974-01-10 ES ES422155A patent/ES422155A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO138146B (no) | 1978-04-03 |
| DD109631A5 (forum.php) | 1974-11-12 |
| CA1008451A (en) | 1977-04-12 |
| BE809592A (fr) | 1974-07-10 |
| DE2363536C3 (de) | 1979-07-26 |
| IE38785L (en) | 1974-07-11 |
| SE407689B (sv) | 1979-04-09 |
| DK133247C (da) | 1976-09-13 |
| ZA738658B (en) | 1974-10-30 |
| US4124757A (en) | 1978-11-07 |
| IL43619A0 (en) | 1974-03-14 |
| DE2363536A1 (de) | 1974-08-01 |
| PL88485B1 (forum.php) | 1976-09-30 |
| AR201121A1 (es) | 1975-02-14 |
| FR2323686B1 (forum.php) | 1978-06-23 |
| JPS5418266B2 (forum.php) | 1979-07-06 |
| NO138146C (no) | 1978-07-12 |
| NL7316269A (forum.php) | 1974-07-15 |
| FR2323686A1 (fr) | 1977-04-08 |
| GB1407381A (en) | 1975-09-24 |
| IL43619A (en) | 1976-04-30 |
| JPS4995998A (forum.php) | 1974-09-11 |
| NL150804B (nl) | 1976-09-15 |
| LU69129A1 (forum.php) | 1975-12-09 |
| HU169851B (forum.php) | 1977-02-28 |
| DK133247B (da) | 1976-04-12 |
| AT331999B (de) | 1976-09-10 |
| DE2363536B2 (de) | 1978-11-23 |
| CH586718A5 (forum.php) | 1977-04-15 |
| IE38785B1 (en) | 1978-06-07 |
| ATA17274A (de) | 1975-12-15 |
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