ES419195A1 - Benzoisoindoline derivatives - Google Patents

Benzoisoindoline derivatives

Info

Publication number
ES419195A1
ES419195A1 ES419195A ES419195A ES419195A1 ES 419195 A1 ES419195 A1 ES 419195A1 ES 419195 A ES419195 A ES 419195A ES 419195 A ES419195 A ES 419195A ES 419195 A1 ES419195 A1 ES 419195A1
Authority
ES
Spain
Prior art keywords
formula
optical antipodes
definition
compounds
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES419195A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1425072A external-priority patent/CH590231A5/en
Priority claimed from CH1130573A external-priority patent/CH605748A5/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES419195A1 publication Critical patent/ES419195A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/62Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Procedure for obtaining benz [F] isoindoline derivatives of formula Ib, **(See formula)** which, according to the definition, also comprises the optical antipodes of these compounds of formula Ib as well as the racemic mixtures of these optical antipodes, in which formula R1 and R2 which are the same or different, each represent hydrogen, halogen or alkyl of 1 to 4 carbon atoms, each of X and Y being hydrogen, in which case rings B and C are linked by a cis bond, or X and Y together form an additional bond, and their acid addition salts ; characterized by comprising: separate group R9, from a compound of formula VI: **(See formula)** which, according to the definition, also includes the optical antipodes of the compounds of formula VI as well as the racemic mixtures of the optical antipodes, and in which formula R1, R2, X and Y are defined as above and R9 is an attractive group of electrodes, conveniently in a solvent, preferably between room temperature and reflux temperature. (Machine-translation by Google Translate, not legally binding)
ES419195A 1972-09-29 1973-09-29 Benzoisoindoline derivatives Expired ES419195A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1425072A CH590231A5 (en) 1972-09-29 1972-09-29 Benzo(f)isoindoline derivs - with antidepressant and analgesic activity
CH1130573A CH605748A5 (en) 1973-08-03 1973-08-03 Benzo(f)isoindoline derivs

Publications (1)

Publication Number Publication Date
ES419195A1 true ES419195A1 (en) 1976-12-16

Family

ID=25708104

Family Applications (4)

Application Number Title Priority Date Filing Date
ES419195A Expired ES419195A1 (en) 1972-09-29 1973-09-29 Benzoisoindoline derivatives
ES443519A Expired ES443519A1 (en) 1972-09-29 1975-12-16 Benzoisoindoline derivatives
ES443518A Expired ES443518A1 (en) 1972-09-29 1975-12-16 Benzoisoindoline derivatives
ES443517A Expired ES443517A1 (en) 1972-09-29 1975-12-16 Benzoisoindoline derivatives

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES443519A Expired ES443519A1 (en) 1972-09-29 1975-12-16 Benzoisoindoline derivatives
ES443518A Expired ES443518A1 (en) 1972-09-29 1975-12-16 Benzoisoindoline derivatives
ES443517A Expired ES443517A1 (en) 1972-09-29 1975-12-16 Benzoisoindoline derivatives

Country Status (18)

Country Link
JP (1) JPS602304B2 (en)
AT (1) AT339891B (en)
CA (1) CA1008865A (en)
DD (2) DD118630A5 (en)
DE (1) DE2348593A1 (en)
DK (1) DK136420B (en)
ES (4) ES419195A1 (en)
FI (1) FI57748C (en)
FR (1) FR2201092B1 (en)
GB (1) GB1449159A (en)
HK (1) HK380A (en)
IE (1) IE39474B1 (en)
IL (1) IL43333A (en)
MY (1) MY8000220A (en)
NL (1) NL7313111A (en)
PH (1) PH12933A (en)
SE (1) SE394110B (en)
SU (1) SU707521A3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2860878D1 (en) * 1977-06-28 1981-10-29 Sandoz Ag New benz(f)isoindolines, their preparation and medicaments containing them
FR2791345B1 (en) * 1999-03-26 2001-05-04 Adir NOVEL BENZO [3,4] CYCLOBUTA [1,2-C] PYRROLE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792374A (en) * 1971-12-08 1973-06-06 Allen & Hanburys Ltd NEW DERIVATIVES OF ISOINDOLINE

Also Published As

Publication number Publication date
ES443518A1 (en) 1977-08-01
ES443519A1 (en) 1977-08-16
IL43333A0 (en) 1973-11-28
FR2201092A1 (en) 1974-04-26
IE39474L (en) 1974-03-29
JPS4970960A (en) 1974-07-09
HK380A (en) 1980-01-11
FR2201092B1 (en) 1977-09-09
FI57748C (en) 1980-10-10
JPS602304B2 (en) 1985-01-21
DE2348593A1 (en) 1974-04-11
AU6085273A (en) 1975-04-10
AT339891B (en) 1977-11-10
MY8000220A (en) 1980-12-31
DD118630A5 (en) 1976-03-12
CA1008865A (en) 1977-04-19
ATA833873A (en) 1977-02-15
FI57748B (en) 1980-06-30
ES443517A1 (en) 1977-08-16
DD114604A5 (en) 1975-08-12
GB1449159A (en) 1976-09-15
SE394110B (en) 1977-06-06
IE39474B1 (en) 1978-10-25
IL43333A (en) 1978-10-31
DK136420B (en) 1977-10-10
DK136420C (en) 1978-03-13
SU707521A3 (en) 1979-12-30
PH12933A (en) 1979-10-17
NL7313111A (en) 1974-04-02

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