ES418036A1 - Procedimiento de preparacion de nuevos compuestos de quina-zolina. - Google Patents
Procedimiento de preparacion de nuevos compuestos de quina-zolina.Info
- Publication number
- ES418036A1 ES418036A1 ES418036A ES418036A ES418036A1 ES 418036 A1 ES418036 A1 ES 418036A1 ES 418036 A ES418036 A ES 418036A ES 418036 A ES418036 A ES 418036A ES 418036 A1 ES418036 A1 ES 418036A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- piperazinylalkyl
- production
- methods
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- PXBFMLJZNCDSMP-UHFFFAOYSA-N 2-Aminobenzamide Chemical compound NC(=O)C1=CC=CC=C1N PXBFMLJZNCDSMP-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00282332A US3819630A (en) | 1972-08-21 | 1972-08-21 | 3-(1-piperazinylalkyl)-2,4-quinazolinedione compounds and methods for their production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES418036A1 true ES418036A1 (es) | 1976-03-01 |
Family
ID=23081024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES418036A Expired ES418036A1 (es) | 1972-08-21 | 1973-08-20 | Procedimiento de preparacion de nuevos compuestos de quina-zolina. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US3819630A (en:Method) |
| JP (1) | JPS4985077A (en:Method) |
| AR (1) | AR200736A1 (en:Method) |
| AT (1) | AT327923B (en:Method) |
| AU (1) | AU476177B2 (en:Method) |
| BE (1) | BE803800A (en:Method) |
| CA (1) | CA990293A (en:Method) |
| CH (1) | CH586695A5 (en:Method) |
| DE (1) | DE2342028A1 (en:Method) |
| DK (1) | DK132758C (en:Method) |
| ES (1) | ES418036A1 (en:Method) |
| FI (1) | FI57937C (en:Method) |
| FR (1) | FR2196803B1 (en:Method) |
| GB (1) | GB1379188A (en:Method) |
| IE (1) | IE38102B1 (en:Method) |
| IL (1) | IL43033A (en:Method) |
| NL (1) | NL7311458A (en:Method) |
| NO (1) | NO138660C (en:Method) |
| PH (1) | PH9220A (en:Method) |
| SE (1) | SE398120B (en:Method) |
| ZA (1) | ZA735728B (en:Method) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3879395A (en) * | 1973-10-23 | 1975-04-22 | Parke Davis & Co | 3-(1-Piperazinylalkylamino)-2-cycloalken-1-one compounds and methods for their production |
| US4268511A (en) * | 1980-03-11 | 1981-05-19 | Berri-Balzac | 3-Amino(1H,3H)quinazoline-2,4-dione derivatives and their therapeutic applications |
| EP0040793B1 (en) * | 1980-05-22 | 1985-08-28 | Masayuki Ishikawa | Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof |
| JPS58159480A (ja) * | 1982-03-17 | 1983-09-21 | Chugai Pharmaceut Co Ltd | 新規なフエニルピペラジン誘導体 |
| JPS5955878A (ja) * | 1982-09-24 | 1984-03-31 | Chugai Pharmaceut Co Ltd | 新規なフエニルピペラジン誘導体 |
| JPS60169467A (ja) * | 1984-02-10 | 1985-09-02 | Chugai Pharmaceut Co Ltd | 新規なフエニルピペラジン誘導体 |
| US4711883A (en) * | 1985-09-30 | 1987-12-08 | Ortho Pharmaceutical Corporation | Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use |
| US5160727A (en) * | 1990-02-13 | 1992-11-03 | Warner-Lambert Company | Tumor cell sensitization method using quinazolinedione derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3274194A (en) * | 1963-03-29 | 1966-09-20 | Miles Lab | Quinazolinedione derivatives |
-
1972
- 1972-08-21 US US00282332A patent/US3819630A/en not_active Expired - Lifetime
-
1973
- 1973-08-20 IL IL43033A patent/IL43033A/en unknown
- 1973-08-20 JP JP48093222A patent/JPS4985077A/ja active Pending
- 1973-08-20 BE BE134748A patent/BE803800A/xx unknown
- 1973-08-20 FR FR7330161A patent/FR2196803B1/fr not_active Expired
- 1973-08-20 CH CH1194973A patent/CH586695A5/xx not_active IP Right Cessation
- 1973-08-20 AR AR249617A patent/AR200736A1/es active
- 1973-08-20 DE DE19732342028 patent/DE2342028A1/de not_active Withdrawn
- 1973-08-20 IE IE1437/73A patent/IE38102B1/xx unknown
- 1973-08-20 AT AT722773A patent/AT327923B/de not_active IP Right Cessation
- 1973-08-20 CA CA179,161A patent/CA990293A/en not_active Expired
- 1973-08-20 NL NL7311458A patent/NL7311458A/xx not_active Application Discontinuation
- 1973-08-20 AU AU59420/73A patent/AU476177B2/en not_active Expired
- 1973-08-20 NO NO3283/73A patent/NO138660C/no unknown
- 1973-08-20 SE SE7311297A patent/SE398120B/xx unknown
- 1973-08-20 FI FI2591/73A patent/FI57937C/fi active
- 1973-08-20 DK DK457173A patent/DK132758C/da active
- 1973-08-20 ES ES418036A patent/ES418036A1/es not_active Expired
- 1973-08-20 GB GB3932673A patent/GB1379188A/en not_active Expired
- 1973-08-21 ZA ZA00735728A patent/ZA735728B/xx unknown
- 1973-09-26 PH PH15053*UA patent/PH9220A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK132758C (da) | 1976-08-23 |
| IL43033A (en) | 1976-09-30 |
| IE38102B1 (en) | 1977-12-21 |
| CA990293A (en) | 1976-06-01 |
| FR2196803A1 (en:Method) | 1974-03-22 |
| AT327923B (de) | 1976-02-25 |
| IE38102L (en) | 1974-02-21 |
| FI57937B (fi) | 1980-07-31 |
| AU476177B2 (en) | 1976-09-16 |
| JPS4985077A (en:Method) | 1974-08-15 |
| CH586695A5 (en:Method) | 1977-04-15 |
| DK132758B (da) | 1976-02-02 |
| NO138660C (no) | 1978-10-18 |
| SE398120B (sv) | 1977-12-05 |
| ATA722773A (de) | 1975-05-15 |
| AU5942073A (en) | 1975-02-20 |
| NL7311458A (en:Method) | 1974-02-25 |
| BE803800A (fr) | 1973-12-17 |
| FI57937C (fi) | 1980-11-10 |
| IL43033A0 (en) | 1973-11-28 |
| PH9220A (en) | 1975-07-10 |
| GB1379188A (en) | 1975-01-02 |
| FR2196803B1 (en:Method) | 1976-05-14 |
| DE2342028A1 (de) | 1974-03-07 |
| NO138660B (no) | 1978-07-10 |
| ZA735728B (en) | 1975-04-30 |
| US3819630A (en) | 1974-06-25 |
| AR200736A1 (es) | 1974-12-13 |
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