ES417127A1 - Un procedimiento de preparacion de 4a-aril-transdecahidroi-soquinoleinas. - Google Patents
Un procedimiento de preparacion de 4a-aril-transdecahidroi-soquinoleinas.Info
- Publication number
- ES417127A1 ES417127A1 ES417127A ES417127A ES417127A1 ES 417127 A1 ES417127 A1 ES 417127A1 ES 417127 A ES417127 A ES 417127A ES 417127 A ES417127 A ES 417127A ES 417127 A1 ES417127 A1 ES 417127A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- see formula
- derivative
- see
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Isoquinoline derivatives isoquinoline derivatives Chemical class 0.000 title abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 229910000104 sodium hydride Inorganic materials 0.000 abstract 1
- 239000012312 sodium hydride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27380672A | 1972-07-20 | 1972-07-20 | |
| US36584373A | 1973-06-01 | 1973-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES417127A1 true ES417127A1 (es) | 1976-04-01 |
Family
ID=26956443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES417127A Expired ES417127A1 (es) | 1972-07-20 | 1973-07-20 | Un procedimiento de preparacion de 4a-aril-transdecahidroi-soquinoleinas. |
Country Status (13)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7509337L (sv) * | 1974-09-23 | 1976-03-24 | Du Pont | Smertstillande foreningar |
| BG30927A3 (bg) * | 1977-12-27 | 1981-09-15 | Eli Lilly And Company | Метод за получаване на транс-4-алфа-фенил-октахидро-1н-2 пиридини |
| CA2064853C (en) * | 1990-06-05 | 1999-08-24 | Hiroshi Nagase | Indole derivatives |
| DE69232484T2 (de) * | 1991-07-05 | 2002-10-31 | Smithkline Beecham S.P.A., Baranzate Di Bollate | Hydroisochinolinderivate |
| IT1307327B1 (it) * | 1995-09-12 | 2001-10-30 | Smithkline Beecham Spa | Derivati idroisochinolinici sostituiti |
-
1973
- 1973-07-18 DE DE19732336559 patent/DE2336559A1/de active Pending
- 1973-07-18 CA CA176,763A patent/CA1024149A/en not_active Expired
- 1973-07-18 DE DE19732351599 patent/DE2351599A1/de active Pending
- 1973-07-19 NL NL7310078A patent/NL7310078A/xx not_active Application Discontinuation
- 1973-07-19 IL IL42790A patent/IL42790A/en unknown
- 1973-07-19 AR AR249168A patent/AR208650A1/es active
- 1973-07-19 GB GB3938775A patent/GB1436377A/en not_active Expired
- 1973-07-19 IE IE1229/73A patent/IE37929B1/xx unknown
- 1973-07-19 HU HUDU206A patent/HU167738B/hu unknown
- 1973-07-19 FR FR7326508A patent/FR2193600B1/fr not_active Expired
- 1973-07-19 IL IL48667A patent/IL48667A/en unknown
- 1973-07-19 GB GB3443873A patent/GB1436376A/en not_active Expired
- 1973-07-20 LU LU68066A patent/LU68066A1/xx unknown
- 1973-07-20 ES ES417127A patent/ES417127A1/es not_active Expired
- 1973-07-20 JP JP48082484A patent/JPS4985075A/ja active Pending
-
1975
- 1975-12-15 IL IL48667A patent/IL48667A0/xx unknown
-
1976
- 1976-02-23 SE SE7602150A patent/SE7602150L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE37929L (en) | 1974-01-20 |
| IE37929B1 (en) | 1977-11-09 |
| FR2193600B1 (enrdf_load_stackoverflow) | 1976-10-22 |
| CA1024149A (en) | 1978-01-10 |
| HU167738B (enrdf_load_stackoverflow) | 1975-12-25 |
| JPS4985075A (enrdf_load_stackoverflow) | 1974-08-15 |
| IL42790A0 (en) | 1973-10-25 |
| FR2193600A1 (enrdf_load_stackoverflow) | 1974-02-22 |
| NL7310078A (enrdf_load_stackoverflow) | 1974-01-22 |
| LU68066A1 (enrdf_load_stackoverflow) | 1973-09-26 |
| SE7602150L (sv) | 1976-02-23 |
| IL42790A (en) | 1976-11-30 |
| GB1436376A (en) | 1976-05-19 |
| AU5820773A (en) | 1975-01-23 |
| GB1436377A (en) | 1976-05-19 |
| IL48667A0 (en) | 1976-02-29 |
| IL48667A (en) | 1976-11-30 |
| DE2336559A1 (de) | 1974-01-31 |
| DE2351599A1 (de) | 1974-01-31 |
| AR208650A1 (es) | 1977-02-28 |
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