ES414870A1 - Procedimiento de preparacion de nuevos derivados de la 6- alfa-metilprednisolona. - Google Patents
Procedimiento de preparacion de nuevos derivados de la 6- alfa-metilprednisolona.Info
- Publication number
- ES414870A1 ES414870A1 ES414870A ES414870A ES414870A1 ES 414870 A1 ES414870 A1 ES 414870A1 ES 414870 A ES414870 A ES 414870A ES 414870 A ES414870 A ES 414870A ES 414870 A1 ES414870 A1 ES 414870A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- product
- methylprednisolone
- translation
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VHRSUDSXCMQTMA-PJHHCJLFSA-N 6alpha-methylprednisolone Chemical compound C([C@@]12C)=CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)[C@@](O)(C(=O)CO)CC[C@H]21 VHRSUDSXCMQTMA-PJHHCJLFSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 3
- 150000001340 alkali metals Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- QMWGSOMVXSRXQX-UHFFFAOYSA-N 3-sulfobenzoic acid Chemical compound OC(=O)C1=CC=CC(S(O)(=O)=O)=C1 QMWGSOMVXSRXQX-UHFFFAOYSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7218035A FR2193576B1 (enrdf_load_stackoverflow) | 1972-05-19 | 1972-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES414870A1 true ES414870A1 (es) | 1976-05-01 |
Family
ID=9098837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES414870A Expired ES414870A1 (es) | 1972-05-19 | 1973-05-18 | Procedimiento de preparacion de nuevos derivados de la 6- alfa-metilprednisolona. |
Country Status (25)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5112816A (ja) * | 1975-04-03 | 1976-01-31 | Wakao Kanao | Tairubaripurekyasutokonkuriitono seizohoho |
| JPS51122118A (en) * | 1975-04-15 | 1976-10-26 | Wakao Kanao | Production of tiled precast concrete |
| US4948533A (en) * | 1984-03-28 | 1990-08-14 | The Upjohn Company | 11a-hydroxy steroid diester |
| US4588718A (en) * | 1984-03-28 | 1986-05-13 | The Upjohn Company | Carboxy containing ester prodrugs of corticosteroids |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3089881A (en) * | 1957-10-29 | 1963-05-14 | Schering Corp | Sulfocarboxylic acid esters of hydroxylated steroids |
-
1972
- 1972-05-19 FR FR7218035A patent/FR2193576B1/fr not_active Expired
-
1973
- 1973-05-04 CH CH638173A patent/CH572068A5/xx not_active IP Right Cessation
- 1973-05-10 PH PH7314601A patent/PH12351A/en unknown
- 1973-05-11 IL IL42250A patent/IL42250A/en unknown
- 1973-05-15 FI FI731564A patent/FI52588C/fi active
- 1973-05-15 CS CS3446A patent/CS165956B2/cs unknown
- 1973-05-15 YU YU1278/73A patent/YU35037B/xx unknown
- 1973-05-16 BE BE131184A patent/BE799615A/xx unknown
- 1973-05-17 HU HURO730A patent/HU165993B/hu unknown
- 1973-05-17 SE SE7306996A patent/SE399711B/xx unknown
- 1973-05-17 ZA ZA733340A patent/ZA733340B/xx unknown
- 1973-05-17 PL PL1973162627A patent/PL85506B1/pl unknown
- 1973-05-18 JP JP48054774A patent/JPS5212777B2/ja not_active Expired
- 1973-05-18 SU SU1916475A patent/SU493961A3/ru active
- 1973-05-18 AU AU55900/73A patent/AU473292B2/en not_active Expired
- 1973-05-18 DD DD170919A patent/DD104787A5/xx unknown
- 1973-05-18 NO NO2058/73A patent/NO138148C/no unknown
- 1973-05-18 NL NL7306962A patent/NL7306962A/xx unknown
- 1973-05-18 ES ES414870A patent/ES414870A1/es not_active Expired
- 1973-05-18 CA CA171,864A patent/CA977746A/en not_active Expired
- 1973-05-19 EG EG186/73A patent/EG11080A/xx active
- 1973-05-21 DK DK277473AA patent/DK133683B/da unknown
- 1973-05-21 GB GB2401373A patent/GB1375357A/en not_active Expired
- 1973-05-21 AT AT441473A patent/AT325221B/de not_active IP Right Cessation
- 1973-05-21 IE IE811/73A patent/IE37657B1/xx unknown
Also Published As
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