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Boehringer Ingelheim Pharma GmbH and Co KG
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Dr Karl Thomae GmbH
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Priority to ES411407ApriorityCriticalpatent/ES411407A1/en
Publication of ES411407A1publicationCriticalpatent/ES411407A1/en
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms
(AREA)
Abstract
Procedure for the preparation of new oxazoles of the general formula I **(See formula)** in which R means a hydrogen atom, an alcohol radical with 1 to 4 carbon atoms substituted by a hydroxy, carboxy or carbalkoxy group, an aliphatic acyl radical with 1 to 6 carbon atoms, saturated or unsaturated, optionally substituted by a hydroxy group, a benzoyl radical optionally substituted by methyl or methoxy groups or halogen atoms, a pyridinecarbonyl or phenylacetyl radical, and its salts physiologically compatible with organic or inorganic acids, characterized in that a 5-halogen derivative is reacted with urea -azepinone- (4) of the general formula II **(See formula)** in which R is as initially defined and Hal represents a chlorine, bromine or iodine atom, or its acid addition salts, in a melt or in a solvent, and a compound obtained from the general formula I is transformed in case then desired in its salt with a physiologically compatible organic or inorganic acid. (Machine-translation by Google Translate, not legally binding)
ES411407A1973-02-081973-02-08Procedure for the preparation of new oxazoles. (Machine-translation by Google Translate, not legally binding)
ExpiredES411407A1
(en)
Procedure for the preparation of new acids 4- (4 bifenilil) -4-hydroxy-butirrics, its esteres or lactonas. (Machine-translation by Google Translate, not legally binding)
A process for the preparation of acids 2- (6-metoxy2'naftil) propionico and 2- (6-metoxy-2-naftil) -1-propanol. (Machine-translation by Google Translate, not legally binding)