ES429772A2 - Procedure for the preparation of bencilamines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of bencilamines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES429772A2
ES429772A2 ES429772A ES429772A ES429772A2 ES 429772 A2 ES429772 A2 ES 429772A2 ES 429772 A ES429772 A ES 429772A ES 429772 A ES429772 A ES 429772A ES 429772 A2 ES429772 A2 ES 429772A2
Authority
ES
Spain
Prior art keywords
denotes
radical
formula
image
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES429772A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742402577 external-priority patent/DE2402577C3/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES429772A2 publication Critical patent/ES429772A2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

2-Aminobenzylamines of the formula I < IMAGE > in which Hal denotes a chlorine or bromine atom R1 denotes a hydrogen, chlorine or bromine atom R2 denotes a hydrogen atom or an alkyl radical having 1 to 3 carbon atoms R3 denotes a cyclohexyl or hydroxycyclohexyl radical and R4 denotes a hydrogen atom or R3 denotes the isopropylaminocarbonylmethyl or morpholinocarbonylmethyl radical and R4 denotes a hydrogen atom or the benzoyl radical are prepared by reacting a compound of the formula II < IMAGE > in which X represents a trialkylammonium or pyridinium radical, with an amine of the formula III < IMAGE > This process is novel and surprisingly gives virtually quantitative yields. The compounds of the formula I and their physiologically tolerable salts with inorganic or organic acids have an antitussive, secretolytic and/or respiratory-stimulating action.
ES429772A 1974-01-19 1974-09-05 Procedure for the preparation of bencilamines. (Machine-translation by Google Translate, not legally binding) Expired ES429772A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19742402577 DE2402577C3 (en) 1974-01-19 Process for the preparation of benzylamines

Publications (1)

Publication Number Publication Date
ES429772A2 true ES429772A2 (en) 1977-03-16

Family

ID=5905201

Family Applications (1)

Application Number Title Priority Date Filing Date
ES429772A Expired ES429772A2 (en) 1974-01-19 1974-09-05 Procedure for the preparation of bencilamines. (Machine-translation by Google Translate, not legally binding)

Country Status (14)

Country Link
JP (2) JPS50101329A (en)
AT (1) AT327876B (en)
BG (1) BG22385A4 (en)
CA (1) CA1050541A (en)
CH (1) CH612663A5 (en)
CS (1) CS167213B2 (en)
DK (1) DK473174A (en)
ES (1) ES429772A2 (en)
FI (1) FI60552C (en)
HU (1) HU167562B (en)
NL (1) NL7410822A (en)
PL (1) PL91730B1 (en)
SE (1) SE439157B (en)
YU (1) YU37110B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT332375B (en) * 1973-04-13 1976-09-27 Thomae Gmbh Dr K PROCESS FOR THE PRODUCTION OF NEW AMINOBENZYLAMINES AND THEIR ACID ADDITION SALTS

Also Published As

Publication number Publication date
AT327876B (en) 1976-02-25
YU37110B (en) 1984-08-31
NL7410822A (en) 1975-07-22
JPS5353624A (en) 1978-05-16
BG22385A4 (en) 1977-02-20
CA1050541A (en) 1979-03-13
FI60552C (en) 1982-02-10
HU167562B (en) 1975-11-28
CH612663A5 (en) 1979-08-15
PL91730B1 (en) 1977-03-31
ATA651074A (en) 1975-05-15
JPS50101329A (en) 1975-08-11
SE7411314L (en) 1975-07-21
DK473174A (en) 1975-09-08
YU239374A (en) 1983-04-27
JPS568022B2 (en) 1981-02-20
CS167213B2 (en) 1976-04-29
DE2402577A1 (en) 1975-12-18
FI247174A (en) 1975-07-20
DE2402577B2 (en) 1976-09-02
FI60552B (en) 1981-10-30
SE439157B (en) 1985-06-03

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