ES409296A1 - Un procedimiento para preparar compuestos heterociclos de- rivados de la perimidina, imidazolina y diacepina. - Google Patents

Un procedimiento para preparar compuestos heterociclos de- rivados de la perimidina, imidazolina y diacepina.

Info

Publication number
ES409296A1
ES409296A1 ES409296A ES409296A ES409296A1 ES 409296 A1 ES409296 A1 ES 409296A1 ES 409296 A ES409296 A ES 409296A ES 409296 A ES409296 A ES 409296A ES 409296 A1 ES409296 A1 ES 409296A1
Authority
ES
Spain
Prior art keywords
compound
group
hydroxyl
halogen
conversion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES409296A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Publication of ES409296A1 publication Critical patent/ES409296A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
ES409296A 1971-01-11 1972-12-05 Un procedimiento para preparar compuestos heterociclos de- rivados de la perimidina, imidazolina y diacepina. Expired ES409296A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB125071*[A GB1366133A (en) 1971-01-11 1971-01-11 Fused ring indole derivatives
GB4095971 1971-09-02
GB5646771 1971-12-06

Publications (1)

Publication Number Publication Date
ES409296A1 true ES409296A1 (es) 1976-03-16

Family

ID=27253859

Family Applications (2)

Application Number Title Priority Date Filing Date
ES398678A Expired ES398678A1 (es) 1971-01-11 1972-01-08 Un procedimiento para preparar un derivado de indol.
ES409296A Expired ES409296A1 (es) 1971-01-11 1972-12-05 Un procedimiento para preparar compuestos heterociclos de- rivados de la perimidina, imidazolina y diacepina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES398678A Expired ES398678A1 (es) 1971-01-11 1972-01-08 Un procedimiento para preparar un derivado de indol.

Country Status (20)

Country Link
JP (1) JPS5531156B2 (es)
AR (1) AR192734A1 (es)
AT (1) AT312595B (es)
AU (1) AU464388B2 (es)
BE (1) BE777911A (es)
CA (1) CA1012150A (es)
CH (1) CH573938A5 (es)
CY (1) CY926A (es)
DK (1) DK150143C (es)
EG (1) EG10888A (es)
ES (2) ES398678A1 (es)
FI (1) FI54120C (es)
FR (1) FR2121699B1 (es)
GB (1) GB1366133A (es)
HK (1) HK52877A (es)
IE (1) IE35956B1 (es)
KE (1) KE2777A (es)
MY (1) MY7800048A (es)
NL (1) NL174251C (es)
SE (1) SE398645B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520611A (en) * 1976-06-11 1978-08-09 Wyeth John & Brother Ltd Fused ring indole derivatives
JPS5845741B2 (ja) * 1977-06-06 1983-10-12 株式会社日立製作所 情報検索装置
ZA824382B (en) * 1981-07-07 1984-02-29 Wyeth John & Brother Ltd Anti-obesity agents
JPS60204057A (ja) * 1984-03-28 1985-10-15 Casio Comput Co Ltd デ−タ記憶機能付小型電子機器
GB8606253D0 (en) * 1986-03-13 1986-04-16 Wyeth John & Brother Ltd Pyrimidoindoles
GB8606254D0 (en) * 1986-03-13 1986-04-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
GB8614246D0 (en) * 1986-06-11 1986-07-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
WO2010090680A1 (en) * 2008-12-15 2010-08-12 Wyeth Llc Substituted oxindole cb2 agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888846A (en) * 1967-03-30 1975-06-10 Hoffmann La Roche Process for 2(2-(1,3-diazacycloalk-2-enyl))benzophenone derivatives and 1,3-diazacycloalkenyl(2,1-a)isoindole derivatives
US3586693A (en) * 1969-07-07 1971-06-22 American Home Prod Imidazo(1,2-a)indolin-9-ols

Also Published As

Publication number Publication date
FR2121699B1 (es) 1975-08-01
JPS5531156B2 (es) 1980-08-15
AR192734A1 (es) 1973-03-14
IE35956L (en) 1972-07-11
DK150143C (da) 1987-06-01
AU3755872A (en) 1973-07-05
IE35956B1 (en) 1976-07-07
JPS4839500A (es) 1973-06-09
CH573938A5 (es) 1976-03-31
SE398645B (sv) 1978-01-09
FR2121699A1 (es) 1972-08-25
BE777911A (fr) 1972-07-11
NL174251B (nl) 1983-12-16
MY7800048A (en) 1978-12-31
FI54120C (fi) 1978-10-10
AU464388B2 (en) 1975-08-28
AT312595B (de) 1974-01-10
KE2777A (en) 1977-10-21
CY926A (en) 1977-12-23
NL174251C (nl) 1984-05-16
ES398678A1 (es) 1975-05-16
FI54120B (fi) 1978-06-30
HK52877A (en) 1977-10-20
GB1366133A (en) 1974-09-11
CA1012150A (en) 1977-06-14
EG10888A (en) 1978-06-30
NL7200415A (es) 1972-07-13
DK150143B (da) 1986-12-15

Similar Documents

Publication Publication Date Title
ES408736A1 (es) Procedimiento para la preparacion de compuestos imidazo- triazinonas.
KR880001583A (ko) 광학적 활성 벤젠설폰아미드 유도체의 제조방법
ES387554A1 (es) Procedimiento para la preparacion de 4-morfolino - tieno (3,2) pirimidinas.
CA1254209A (en) 3,7-DIAZA-BICYCLO-(3,3,1)-NONANE COMPOUNDS; COMPOSITIONS CONTAINING THEM; PREPARATION AND USE
ES409296A1 (es) Un procedimiento para preparar compuestos heterociclos de- rivados de la perimidina, imidazolina y diacepina.
ES385627A2 (es) Procedimiento para la preparacion de derivados de morfoli- na.
ES323083A1 (es) Procedimiento para la fabricacion de derivados de naftaleno.
ES384182A1 (es) Procedimiento para la preparacion de nuevos butanoles ter- ciarios basicamente sustituidos.
ATE17577T1 (de) Verfahren zur herstellung von 2-benzoxazolon und seinen derivaten aus orthonitrophenolen und carbonmonoxid.
ES419386A1 (es) Un procedimiento para la preparacion de nuevos derivados deindenopirrol.
ES394894A1 (es) Procedimiento para la obtencion de acidos fenilacetohidro- xamicos.
ES420538A1 (es) Procedimiento para la obtencion de 1,2,4-triazina-1,4-di-n-oxidos.
MX3037E (es) Procedimiento para preparar derivados de di oxo lano
ES386460A1 (es) Un procedimiento para la preparacion de acidos indolaceti- cos y derivados.
GB1378403A (en) Process for the preparation of 3-2h-isoquinolones
ES291879A1 (es) Procedimiento para la fabricacion de nuevos 1,3-dioxanos basicos y de sus sales
GB1110725A (en) Process for preparing cyloheptimidazolinium halides
ES413742A1 (es) Un procedimiento para la preparacion de compuestos de acidol-alfa-hidrazino-betaf-fenilpropionico.
ES386294A1 (es) Procedimiento de sintesis quimica para la preparacion de 2,6-dietanolamino 4,8-dipiperidino-pirimidino-(5,4 d)-piri- midina.
ES420295A1 (es) Procedimiento para preparar una butanodiamina-1,3.
ES362824A1 (es) Procedimiento de obtencion de compuestos antiulcerosos.
ES329559A1 (es) Un procedimiento para producir dihidro-1,2,4-benztriazinas sustituidas.
ES321534A1 (es) Procedimiento para la preparacion de compuestos de dihidrodibenzociclohepteno.
GB935406A (en) Novel piperazine derivatives and a process for the manufacture thereof
ES390235A1 (es) Procedimiento para la preparacion de derivados de penicili-na.