CA1012150A - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
CA1012150A
CA1012150A CA157,326A CA157326A CA1012150A CA 1012150 A CA1012150 A CA 1012150A CA 157326 A CA157326 A CA 157326A CA 1012150 A CA1012150 A CA 1012150A
Authority
CA
Canada
Prior art keywords
indole derivatives
indole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA157,326A
Other versions
CA157326S (en
Inventor
Robin M. Black
Alan C. White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Application granted granted Critical
Publication of CA1012150A publication Critical patent/CA1012150A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CA157,326A 1971-01-11 1972-11-23 Indole derivatives Expired CA1012150A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB125071*[A GB1366133A (en) 1971-01-11 1971-01-11 Fused ring indole derivatives
GB4095971 1971-09-02
GB5646771 1971-12-06

Publications (1)

Publication Number Publication Date
CA1012150A true CA1012150A (en) 1977-06-14

Family

ID=27253859

Family Applications (1)

Application Number Title Priority Date Filing Date
CA157,326A Expired CA1012150A (en) 1971-01-11 1972-11-23 Indole derivatives

Country Status (20)

Country Link
JP (1) JPS5531156B2 (en)
AR (1) AR192734A1 (en)
AT (1) AT312595B (en)
AU (1) AU464388B2 (en)
BE (1) BE777911A (en)
CA (1) CA1012150A (en)
CH (1) CH573938A5 (en)
CY (1) CY926A (en)
DK (1) DK150143C (en)
EG (1) EG10888A (en)
ES (2) ES398678A1 (en)
FI (1) FI54120C (en)
FR (1) FR2121699B1 (en)
GB (1) GB1366133A (en)
HK (1) HK52877A (en)
IE (1) IE35956B1 (en)
KE (1) KE2777A (en)
MY (1) MY7800048A (en)
NL (1) NL174251C (en)
SE (1) SE398645B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520611A (en) * 1976-06-11 1978-08-09 Wyeth John & Brother Ltd Fused ring indole derivatives
JPS5845741B2 (en) * 1977-06-06 1983-10-12 株式会社日立製作所 information retrieval device
ZA824382B (en) * 1981-07-07 1984-02-29 Wyeth John & Brother Ltd Anti-obesity agents
JPS60204057A (en) * 1984-03-28 1985-10-15 Casio Comput Co Ltd Small-sized electronic apparatus with data storage function
GB8606253D0 (en) * 1986-03-13 1986-04-16 Wyeth John & Brother Ltd Pyrimidoindoles
GB8606254D0 (en) * 1986-03-13 1986-04-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
GB8614246D0 (en) * 1986-06-11 1986-07-16 Wyeth John & Brother Ltd Substituted pyrimidoindoles
WO2010090680A1 (en) * 2008-12-15 2010-08-12 Wyeth Llc Substituted oxindole cb2 agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888846A (en) * 1967-03-30 1975-06-10 Hoffmann La Roche Process for 2(2-(1,3-diazacycloalk-2-enyl))benzophenone derivatives and 1,3-diazacycloalkenyl(2,1-a)isoindole derivatives
US3586693A (en) * 1969-07-07 1971-06-22 American Home Prod Imidazo(1,2-a)indolin-9-ols

Also Published As

Publication number Publication date
IE35956B1 (en) 1976-07-07
DK150143B (en) 1986-12-15
DK150143C (en) 1987-06-01
JPS4839500A (en) 1973-06-09
FI54120C (en) 1978-10-10
FI54120B (en) 1978-06-30
AR192734A1 (en) 1973-03-14
EG10888A (en) 1978-06-30
JPS5531156B2 (en) 1980-08-15
GB1366133A (en) 1974-09-11
HK52877A (en) 1977-10-20
FR2121699A1 (en) 1972-08-25
NL174251B (en) 1983-12-16
FR2121699B1 (en) 1975-08-01
SE398645B (en) 1978-01-09
ES409296A1 (en) 1976-03-16
CY926A (en) 1977-12-23
IE35956L (en) 1972-07-11
NL7200415A (en) 1972-07-13
KE2777A (en) 1977-10-21
MY7800048A (en) 1978-12-31
CH573938A5 (en) 1976-03-31
BE777911A (en) 1972-07-11
ES398678A1 (en) 1975-05-16
NL174251C (en) 1984-05-16
AT312595B (en) 1974-01-10
AU464388B2 (en) 1975-08-28
AU3755872A (en) 1973-07-05

Similar Documents

Publication Publication Date Title
CA1006875A (en) Indole derivatives
CA983932A (en) Indole derivatives
AU468250B2 (en) 3-nitropyrazole derivatives
AU462723B2 (en) 2-nitro-5-imidazolyaldehyde derivatives
CA1012150A (en) Indole derivatives
AU461957B2 (en) Lumilysergol derivatives
CA1017335A (en) Triazolyl-ethenyl-phenylene derivatives
AU463679B2 (en) Dibenzocycloheptadioxolan derivatives
AU470552B2 (en) Aminocephalosporin derivatives
AU472069B2 (en) Dibenzoxirenazepine derivatives
GB1405800A (en) Indole derivatives
CA882140A (en) Indole derivatives
AU438840B2 (en) Indole derivatives
AU464145B2 (en) Indole derivatives
CA861515A (en) Indole derivatives
CA876724A (en) Indole derivatives
CA878514A (en) Indole derivatives
CA973882A (en) Indoles
CA866825A (en) 2-benzoyl-3-(2-tertiaryamino-ethoxy)-indole derivatives
AU2912871A (en) Indole derivatives
CA877321A (en) Ndole derivatives
CA882717A (en) Indole alkaloid derivatives
AU475691B2 (en) 7-amino-indazole derivatives
AU458249B2 (en) Tropan-3-ol derivatives
AU454731B2 (en) Pyrazinylurea derivatives