ES406846A1 - Cyclic ketones - Google Patents
Cyclic ketonesInfo
- Publication number
- ES406846A1 ES406846A1 ES406846A ES406846A ES406846A1 ES 406846 A1 ES406846 A1 ES 406846A1 ES 406846 A ES406846 A ES 406846A ES 406846 A ES406846 A ES 406846A ES 406846 A1 ES406846 A1 ES 406846A1
- Authority
- ES
- Spain
- Prior art keywords
- chr
- lower alkyl
- phenyl
- hydrogen
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Abstract
A method of inhibiting the action of androgens, characterized by administering to a subject exhibiting an overabundance of androgen action an effective amount of an arylidene cyclone of the formula ** (See formula) ** where Y is -CHR-, -CHR-CHR- or -CHR-CHR-CHR-; each of the radicals R is independently hydrogen, methyl, ethyl or propyl; Ar is phenyl, furyl, thienyl, styryl, naphthyl or a monosubstituted or disubstituted derivative of each of them, the substituents being selected from the group consisting of hydroxy, lower alkoxy, lower alkyl, methylenedioxy, amino, lower alkyl, dialkyl - (lower) amino, nitro and halogen; R1 is hydrogen, cyclohexyl, phenyl, lower alkyl cyclohexyl or lower alkyl phenyl and R2 is hydrogen; R1 and R2 together represent -CH-Ar as defined herein; or R1 and R2 together with the portion of the cyclone ring to which they are attached represent ** (See formula) ** or a lower alkyl or lower alkoxy derivative thereof. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18212371A | 1971-09-20 | 1971-09-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES406846A1 true ES406846A1 (en) | 1976-05-01 |
Family
ID=22667147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES406846A Expired ES406846A1 (en) | 1971-09-20 | 1972-09-19 | Cyclic ketones |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS4836155A (en) |
AU (1) | AU463813B2 (en) |
BE (1) | BE788991A (en) |
CA (1) | CA986015A (en) |
DD (1) | DD103811A5 (en) |
DE (1) | DE2245518A1 (en) |
ES (1) | ES406846A1 (en) |
FR (1) | FR2154536B1 (en) |
GB (1) | GB1394717A (en) |
IE (1) | IE36663B1 (en) |
IL (1) | IL40220A (en) |
NL (1) | NL7212741A (en) |
PH (1) | PH10556A (en) |
PL (1) | PL85198B1 (en) |
ZA (1) | ZA725886B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4857029A (en) * | 1971-09-22 | 1973-08-10 | ||
JPS493029A (en) * | 1972-04-27 | 1974-01-11 | ||
JPS5074038A (en) * | 1973-11-07 | 1975-06-18 | ||
FR2399426A1 (en) * | 1977-08-04 | 1979-03-02 | Unicler | A-BENZYLIDENE-CYCLOALCANONES AND CORRESPONDING ALCOHOLS AND THEIR APPLICATION IN THERAPEUTICS |
DE2951101A1 (en) * | 1979-12-19 | 1981-06-25 | Merck Patent Gmbh, 6100 Darmstadt | METHOD FOR PRODUCING AZIDOBENZAL COMPOUNDS |
FR2641277B1 (en) * | 1988-12-29 | 1994-08-26 | Rhone Poulenc Agrochimie | AZOLYLMETHYLCYCLOPENTANE OR CYCLOPENTENE BENZOLIDENE AND USE AS A FUNGICIDE |
CA2006309C (en) * | 1988-12-29 | 2001-12-18 | Jean Hutt | Azolylmethylcyclopentane benzylidene fungicide |
FR2649101B1 (en) * | 1989-06-30 | 1994-10-28 | Rhone Poulenc Agrochimie | AZOLYLMETHYLCYCLOHEXANE BENZILIDENE AND USE AS A FUNGICIDE |
JPH10273467A (en) * | 1997-01-29 | 1998-10-13 | Snow Brand Milk Prod Co Ltd | New tetralone or benzopyranone derivative and its production |
US6162810A (en) * | 1997-11-17 | 2000-12-19 | The Regents Of The University Of California | Inadone and tetralone compounds for inhibiting cell proliferation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1160689A (en) * | 1953-04-13 | 1958-07-24 | Anton Von Waldheim Chemisch Ph | Method for preparing divanillydene-cyclohexanone |
FR64M (en) * | 1960-07-22 | 1961-01-09 | ||
FR1867M (en) * | 1962-04-12 | 1963-06-17 | Egema | New composition intended in particular for the treatment of cholesterolemia. |
FR1414456A (en) * | 1964-11-19 | 1965-10-15 | Eastman Kodak Co | Process for the preparation of 2-alkylbutanones and products obtained by carrying out this process |
-
0
- BE BE788991D patent/BE788991A/en unknown
-
1972
- 1972-08-28 ZA ZA725886A patent/ZA725886B/en unknown
- 1972-08-28 IL IL40220A patent/IL40220A/en unknown
- 1972-08-30 CA CA150,548A patent/CA986015A/en not_active Expired
- 1972-08-31 AU AU46183/72A patent/AU463813B2/en not_active Expired
- 1972-09-01 IE IE1189/72A patent/IE36663B1/en unknown
- 1972-09-07 PH PH13872A patent/PH10556A/en unknown
- 1972-09-15 DE DE2245518A patent/DE2245518A1/en active Pending
- 1972-09-18 PL PL1972157806A patent/PL85198B1/pl unknown
- 1972-09-19 GB GB4337572A patent/GB1394717A/en not_active Expired
- 1972-09-19 ES ES406846A patent/ES406846A1/en not_active Expired
- 1972-09-20 JP JP47093762A patent/JPS4836155A/ja active Pending
- 1972-09-20 FR FR7233325A patent/FR2154536B1/fr not_active Expired
- 1972-09-20 NL NL7212741A patent/NL7212741A/xx not_active Application Discontinuation
- 1972-09-20 DD DD165766A patent/DD103811A5/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU463813B2 (en) | 1975-08-07 |
PL85198B1 (en) | 1976-04-30 |
NL7212741A (en) | 1973-03-22 |
PH10556A (en) | 1977-06-08 |
IE36663B1 (en) | 1977-01-19 |
ZA725886B (en) | 1974-04-24 |
FR2154536B1 (en) | 1976-07-02 |
DE2245518A1 (en) | 1973-04-26 |
GB1394717A (en) | 1975-05-21 |
CA986015A (en) | 1976-03-23 |
IL40220A0 (en) | 1972-10-29 |
FR2154536A1 (en) | 1973-05-11 |
JPS4836155A (en) | 1973-05-28 |
IL40220A (en) | 1976-07-30 |
BE788991A (en) | 1973-03-19 |
AU4618372A (en) | 1974-03-07 |
IE36663L (en) | 1973-03-20 |
DD103811A5 (en) | 1974-02-12 |
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