ES402608A1 - Procedimiento para el desdoblamiento de racematos de d, 1- fenilpropanolamina con acidos opticamente activos. - Google Patents
Procedimiento para el desdoblamiento de racematos de d, 1- fenilpropanolamina con acidos opticamente activos.Info
- Publication number
- ES402608A1 ES402608A1 ES402608A ES402608A ES402608A1 ES 402608 A1 ES402608 A1 ES 402608A1 ES 402608 A ES402608 A ES 402608A ES 402608 A ES402608 A ES 402608A ES 402608 A1 ES402608 A1 ES 402608A1
- Authority
- ES
- Spain
- Prior art keywords
- phenylpropanolamine
- optically active
- group
- resolution
- thiazolidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- DLNKOYKMWOXYQA-CBAPKCEASA-N (-)-norephedrine Chemical compound C[C@H](N)[C@H](O)C1=CC=CC=C1 DLNKOYKMWOXYQA-CBAPKCEASA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- -1 alcohol radical Chemical class 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- PZCAZWWYYBZBPV-UHFFFAOYSA-N o-(1-phenylpropyl)hydroxylamine Chemical class CCC(ON)C1=CC=CC=C1 PZCAZWWYYBZBPV-UHFFFAOYSA-N 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- DZLNHFMRPBPULJ-UHFFFAOYSA-N thioproline Chemical compound OC(=O)C1CSCN1 DZLNHFMRPBPULJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712138121 DE2138121C3 (de) | 1971-07-30 | 1971-07-30 | Verfahren zur Racematspaltung von d, i - 1-Phenyl-2-amino-l-propanoI |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES402608A1 true ES402608A1 (es) | 1975-04-16 |
Family
ID=5815276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES402608A Expired ES402608A1 (es) | 1971-07-30 | 1972-05-10 | Procedimiento para el desdoblamiento de racematos de d, 1- fenilpropanolamina con acidos opticamente activos. |
Country Status (12)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2304055C3 (de) * | 1973-01-27 | 1982-04-29 | Degussa Ag, 6000 Frankfurt | Verfahren zur Gewinnung von D- Penicillamin |
| US4237134A (en) | 1976-12-03 | 1980-12-02 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
| US4237129A (en) | 1976-12-03 | 1980-12-02 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
| US4192878A (en) | 1976-12-03 | 1980-03-11 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
| US4282235A (en) | 1978-05-22 | 1981-08-04 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
| DE3134129A1 (de) * | 1981-08-28 | 1983-03-17 | Degussa Ag, 6000 Frankfurt | Verfahren zur trennung des racemats (1rs: 2sr)-2-amino-1-phenyl-propan-1-ol |
| US4463176A (en) * | 1982-09-13 | 1984-07-31 | Mead Johnson & Company | Process for resolution of optical isomers |
| ES2328502T3 (es) | 2004-04-15 | 2009-11-13 | Emmellen Biotech Pharmaceuticals Limited | Procedimiento para la preparacion de 1-eritro-2-amino-1-fenil-1-propanol optimamente activo. |
-
0
- BE BE786963D patent/BE786963A/xx not_active IP Right Cessation
-
1971
- 1971-07-30 DE DE19712138121 patent/DE2138121C3/de not_active Expired
-
1972
- 1972-05-10 ES ES402608A patent/ES402608A1/es not_active Expired
- 1972-05-26 DD DD16330372A patent/DD97196A5/xx unknown
- 1972-06-01 FI FI154472A patent/FI55987C/fi active
- 1972-06-20 CH CH921872A patent/CH578489A5/xx not_active IP Right Cessation
- 1972-06-27 FR FR7223220A patent/FR2147955B1/fr not_active Expired
- 1972-07-26 GB GB3487472A patent/GB1385409A/en not_active Expired
- 1972-07-27 AT AT646972A patent/AT314503B/de not_active IP Right Cessation
- 1972-07-28 IT IT5184472A patent/IT1035050B/it active
- 1972-07-28 CA CA148,202A patent/CA1001174A/en not_active Expired
- 1972-07-31 JP JP7684872A patent/JPS5525180B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BE786963A (fr) | 1973-01-29 |
| FR2147955A1 (enrdf_load_stackoverflow) | 1973-03-11 |
| GB1385409A (en) | 1975-02-26 |
| IT1035050B (it) | 1979-10-20 |
| AT314503B (de) | 1974-04-10 |
| FI55987B (fi) | 1979-07-31 |
| FI55987C (fi) | 1979-11-12 |
| DE2138121A1 (de) | 1973-02-08 |
| JPS5525180B1 (enrdf_load_stackoverflow) | 1980-07-04 |
| DE2138121B2 (de) | 1979-08-02 |
| DE2138121C3 (de) | 1980-04-10 |
| CA1001174A (en) | 1976-12-07 |
| FR2147955B1 (enrdf_load_stackoverflow) | 1976-03-12 |
| DD97196A5 (enrdf_load_stackoverflow) | 1973-04-20 |
| CH578489A5 (enrdf_load_stackoverflow) | 1976-08-13 |
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