ES373753A1 - Un procedimiento para preparar benzoindenos. - Google Patents

Un procedimiento para preparar benzoindenos.

Info

Publication number
ES373753A1
ES373753A1 ES373753A ES373753A ES373753A1 ES 373753 A1 ES373753 A1 ES 373753A1 ES 373753 A ES373753 A ES 373753A ES 373753 A ES373753 A ES 373753A ES 373753 A1 ES373753 A1 ES 373753A1
Authority
ES
Spain
Prior art keywords
group
lower alkyl
formula
hydrogen
methylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES373753A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES373753A1 publication Critical patent/ES373753A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/653Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J15/00Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • C07J15/005Retrosteroids (9 beta 10 alfa)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16Benz[e]indenes; Hydrogenated benz[e]indenes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES373753A 1968-11-22 1969-11-21 Un procedimiento para preparar benzoindenos. Expired ES373753A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77831468A 1968-11-22 1968-11-22

Publications (1)

Publication Number Publication Date
ES373753A1 true ES373753A1 (es) 1973-04-16

Family

ID=25112933

Family Applications (5)

Application Number Title Priority Date Filing Date
ES373751A Expired ES373751A1 (es) 1968-11-22 1969-11-21 Un procedimiento para la preparacion de nuevos derivados deisoxazol.
ES373752A Expired ES373752A1 (es) 1968-11-22 1969-11-21 Un procedimiento para la preparacion de nuevos derivados deisoxazol.
ES373753A Expired ES373753A1 (es) 1968-11-22 1969-11-21 Un procedimiento para preparar benzoindenos.
ES373754A Expired ES373754A1 (es) 1968-11-22 1969-11-22 Un procedimiento para la preparacion de esteroides.
ES401968A Expired ES401968A1 (es) 1968-11-22 1972-04-21 Procedimiento para la preparacion de perhidrobenzindenos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES373751A Expired ES373751A1 (es) 1968-11-22 1969-11-21 Un procedimiento para la preparacion de nuevos derivados deisoxazol.
ES373752A Expired ES373752A1 (es) 1968-11-22 1969-11-21 Un procedimiento para la preparacion de nuevos derivados deisoxazol.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES373754A Expired ES373754A1 (es) 1968-11-22 1969-11-22 Un procedimiento para la preparacion de esteroides.
ES401968A Expired ES401968A1 (es) 1968-11-22 1972-04-21 Procedimiento para la preparacion de perhidrobenzindenos.

Country Status (19)

Country Link
US (1) US3700661A (es)
JP (1) JPS5022031B1 (es)
AT (8) AT294331B (es)
BE (4) BE742088A (es)
BR (4) BR6914373D0 (es)
CA (2) CA918669A (es)
CH (10) CH537938A (es)
DE (3) DE1958601A1 (es)
DK (4) DK130117B (es)
ES (5) ES373751A1 (es)
FI (1) FI47572C (es)
FR (4) FR2030078A1 (es)
GB (9) GB1298217A (es)
IE (1) IE33651B1 (es)
IL (2) IL33369A (es)
NL (4) NL6917499A (es)
NO (1) NO133806C (es)
PH (2) PH11342A (es)
SE (5) SE364715B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984428A (en) * 1968-11-22 1976-10-05 Hoffmann-La Roche Inc. Isoxazolyl-substituted perhydrobenzindenes
US3994930A (en) * 1970-08-26 1976-11-30 Hoffmann-La Roche Inc. 6-(3-Cyanopropyl)-2-vinyl tetrahydropyran-2-ol and its tautomer
US3991084A (en) * 1970-08-26 1976-11-09 Hoffmann-La Roche Inc. Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor
US3873562A (en) * 1972-06-05 1975-03-25 Hoffmann La Roche 1-(4-Isoxazolyl)-7-hydroxy-3-heptanones
US3900491A (en) * 1972-06-05 1975-08-19 Hoffmann La Roche 1-(4-isoxazolyl)-7-hydroxy-2-hydroxyimino heptanes
US3873561A (en) * 1972-06-05 1975-03-25 Hoffmann La Roche 7-(4-Isoxazolyl)-5-oxo-heptanals
US3994926A (en) * 1973-05-24 1976-11-30 Hoffmann-La Roche Inc. Aryl ketals of polycyclic oxo compounds and processes
US3855209A (en) * 1973-09-04 1974-12-17 Eastman Kodak Co Synthesis of indolininium methine dyes
US4054583A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one
US6030970A (en) * 1995-08-02 2000-02-29 Smithkline Beecham Corporation Endothelin receptor antagonists
DE69626986T2 (de) * 1995-08-02 2004-02-05 Smithkline Beecham Corp. Endothelinrezeptorantagonist
US6136828A (en) * 1996-02-01 2000-10-24 Smithkline Beecham Corporation Endothelin receptor antagonists
US6174906B1 (en) 1999-10-01 2001-01-16 Smithkline Beecham Corporation Endothelin receptor antagonists

Also Published As

Publication number Publication date
CH537938A (de) 1973-07-31
DE1958600C3 (de) 1980-08-07
PH11342A (en) 1977-11-02
AT292694B (de) 1971-09-10
CH561192A5 (es) 1975-04-30
GB1298219A (en) 1972-11-29
IE33651L (en) 1970-05-22
CH567489A5 (es) 1975-10-15
GB1298214A (en) 1972-11-29
CH574890A5 (es) 1976-04-30
AT294832B (de) 1971-12-10
GB1298212A (en) 1972-11-29
BE742089A (es) 1970-05-25
NL6917554A (es) 1970-05-26
SE376422B (es) 1975-05-26
US3700661A (en) 1972-10-24
DE1958608A1 (de) 1970-06-18
DE1958600B2 (de) 1979-11-29
DK130117B (da) 1974-12-23
NL6917557A (es) 1970-05-26
GB1298216A (en) 1972-11-29
FR2024920A1 (es) 1970-09-04
SE364715B (es) 1974-03-04
BR6914375D0 (pt) 1973-04-19
SE354657B (es) 1973-03-19
CH568314A5 (es) 1975-10-31
ES373751A1 (es) 1972-02-01
ES373754A1 (es) 1972-04-01
AT304772B (de) 1973-01-25
GB1298211A (en) 1972-11-29
GB1298215A (en) 1972-11-29
FR2024919A1 (es) 1970-09-04
BR6914374D0 (pt) 1973-04-19
AT295757B (de) 1972-01-25
DK129090B (da) 1974-08-19
FR2024918A1 (es) 1970-09-04
IL42366A0 (en) 1973-07-30
PH10667A (en) 1977-08-02
CH567523A5 (es) 1975-10-15
BE742087A (es) 1970-05-25
DK127975B (da) 1974-02-11
CH529774A (de) 1972-10-31
CH567490A5 (es) 1975-10-15
ES401968A1 (es) 1976-04-16
BR6914372D0 (pt) 1973-02-08
IE33651B1 (en) 1974-09-18
SE361887B (es) 1973-11-19
JPS5022031B1 (es) 1975-07-28
DK130117C (es) 1975-06-09
AT299463B (de) 1972-06-26
CH537942A (de) 1973-07-31
NO133806B (es) 1976-03-22
BE742088A (es) 1970-05-25
SE355801B (es) 1973-05-07
FR2030078A1 (es) 1970-10-30
NL6917499A (es) 1970-05-26
NO133806C (es) 1976-06-30
BR6914373D0 (pt) 1973-02-08
DK126655B (da) 1973-08-06
CH578547A5 (es) 1976-08-13
BE742090A (es) 1970-05-25
AT308981B (de) 1973-07-25
FI47572C (fi) 1974-01-10
ES373752A1 (es) 1973-04-16
DE1958600A1 (de) 1970-07-09
GB1298217A (en) 1972-11-29
GB1298218A (en) 1972-11-29
AT292695B (de) 1971-09-10
CA944770A (en) 1974-04-02
FI47572B (es) 1973-10-01
NL6917574A (es) 1970-05-26
AT294331B (de) 1971-11-25
IL33369A (en) 1973-10-25
IL33369A0 (en) 1970-01-29
GB1298213A (en) 1972-11-29
CA918669A (en) 1973-01-09
DE1958601A1 (de) 1970-06-18

Similar Documents

Publication Publication Date Title
ES373753A1 (es) Un procedimiento para preparar benzoindenos.
ES395494A1 (es) Procedimiento para la obtencion de derivados de aminopropa-nol.
ES323287A1 (es) Procedimiento para preparar compuestos de pirrolindazol sustituido.
ES451466A1 (es) Procedimiento para la preparacion de nuevos derivados de 5- tiazol-metanoamina.
ES419839A1 (es) Procedimiento para preparar derivados de metilendiamina sustituidos.
ES429020A1 (es) Procedimiento para preparar nuevos derivados de tiazol-5- metanol.
ES412047A1 (es) Un procedimiento para la preparacion de dihidrocumarina o una alcohil-dihidrocumarina.
ES419386A1 (es) Un procedimiento para la preparacion de nuevos derivados deindenopirrol.
ES394504A1 (es) Un procedimiento para la preparacion de compuestos trici- clicos.
ES364980A1 (es) Un metodo para preparar nuevos derivados de adamantano.
ES380390A1 (es) Procedimiento para la preparacion de un compuesto de 5-ni- tro-furil-pirazol.
ES274909A1 (es) Procedimiento para la preparaciën de nuevos derivados de iminodibencilo
ES412799A1 (es) Un procedimiento para preparar alcoholes alcohilsulfonilme-tilbencilicos.
ES390754A1 (es) Procedimiento para la preparacion de nuevos derivados de tiazoloquinolina.
ES442612A1 (es) Procedimiento para la obtencion de nuevos derivados de iso- quinoleina.
ES442051A1 (es) Procedimiento para preparar aminoglicosidos de 2-deoxies- treptamina.
ES459871A1 (es) Procedimiento para la obtencion de sales de hidrocarbil-tio-etilaminas.
ES321807A1 (es) Procedimiento para la sintesis de nuevos derivados de la 1,2,3,6-tetrahidropiridina.
ES415653A1 (es) Un procedimiento para la preparacion de derivados antiame- bicos de la benzo (a)-quinolicidina.
ES313335A1 (es) Un metodo de preparar nuevos compuestos de glioxalilo
ES437041A1 (es) Un procedimiento para preparar derivados de 1-ftalazona.
ES341698A1 (es) Procedimiento para la produccion de nuevas 1,2,3,4-tetrahi-dro-1-piridil-isoquinoleinas.
ES272911A3 (es) Procedimiento para la producciën de nuevos aminoalcoholes
ES279961A1 (es) Procedimiento de preparación de esteroides de la serie del estrano y del lumiestrano
ES438725A1 (es) Un procedimiento de preparacion de derivados sustituidos del acido prostanoico.