AT294832B - Verfahren zur Herstellung von neuen Isoxazolderivaten, deren Ketalen und Salzen - Google Patents
Verfahren zur Herstellung von neuen Isoxazolderivaten, deren Ketalen und SalzenInfo
- Publication number
- AT294832B AT294832B AT899970A AT899970A AT294832B AT 294832 B AT294832 B AT 294832B AT 899970 A AT899970 A AT 899970A AT 899970 A AT899970 A AT 899970A AT 294832 B AT294832 B AT 294832B
- Authority
- AT
- Austria
- Prior art keywords
- ketals
- salts
- production
- isoxazole derivatives
- new isoxazole
- Prior art date
Links
- 150000002545 isoxazoles Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
- C07J15/005—Retrosteroids (9 beta 10 alfa)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77831468A | 1968-11-22 | 1968-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT294832B true AT294832B (de) | 1971-12-10 |
Family
ID=25112933
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT1089069A AT294331B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung neuer Isoxazolderivate |
| AT877270A AT299463B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung neuer Isoxazolderivate |
| AT464671A AT308981B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von neuen Perhydrobenzindenen |
| AT1089169A AT304772B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von des-A-Steroiden |
| AT899970A AT294832B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von neuen Isoxazolderivaten, deren Ketalen und Salzen |
| AT1088969A AT292694B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von neuen Isoxazolderivaten, deren Ketalen und Salzen |
| AT1089269A AT295757B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von Benzindenen |
| AT877370A AT292695B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung neuer Isoxazolderivate |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT1089069A AT294331B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung neuer Isoxazolderivate |
| AT877270A AT299463B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung neuer Isoxazolderivate |
| AT464671A AT308981B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von neuen Perhydrobenzindenen |
| AT1089169A AT304772B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von des-A-Steroiden |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT1088969A AT292694B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von neuen Isoxazolderivaten, deren Ketalen und Salzen |
| AT1089269A AT295757B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung von Benzindenen |
| AT877370A AT292695B (de) | 1968-11-22 | 1969-11-21 | Verfahren zur Herstellung neuer Isoxazolderivate |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3700661A (de) |
| JP (1) | JPS5022031B1 (de) |
| AT (8) | AT294331B (de) |
| BE (4) | BE742087A (de) |
| BR (4) | BR6914374D0 (de) |
| CA (2) | CA918669A (de) |
| CH (10) | CH529774A (de) |
| DE (3) | DE1958601A1 (de) |
| DK (4) | DK130117B (de) |
| ES (5) | ES373753A1 (de) |
| FI (1) | FI47572C (de) |
| FR (4) | FR2024920A1 (de) |
| GB (9) | GB1298218A (de) |
| IE (1) | IE33651B1 (de) |
| IL (2) | IL33369A (de) |
| NL (4) | NL6917499A (de) |
| NO (1) | NO133806C (de) |
| PH (2) | PH11342A (de) |
| SE (5) | SE376422B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3984428A (en) * | 1968-11-22 | 1976-10-05 | Hoffmann-La Roche Inc. | Isoxazolyl-substituted perhydrobenzindenes |
| US3994930A (en) * | 1970-08-26 | 1976-11-30 | Hoffmann-La Roche Inc. | 6-(3-Cyanopropyl)-2-vinyl tetrahydropyran-2-ol and its tautomer |
| US3991084A (en) * | 1970-08-26 | 1976-11-09 | Hoffmann-La Roche Inc. | Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor |
| US3873562A (en) * | 1972-06-05 | 1975-03-25 | Hoffmann La Roche | 1-(4-Isoxazolyl)-7-hydroxy-3-heptanones |
| US3873561A (en) * | 1972-06-05 | 1975-03-25 | Hoffmann La Roche | 7-(4-Isoxazolyl)-5-oxo-heptanals |
| US3900491A (en) * | 1972-06-05 | 1975-08-19 | Hoffmann La Roche | 1-(4-isoxazolyl)-7-hydroxy-2-hydroxyimino heptanes |
| US3994926A (en) * | 1973-05-24 | 1976-11-30 | Hoffmann-La Roche Inc. | Aryl ketals of polycyclic oxo compounds and processes |
| US3855209A (en) * | 1973-09-04 | 1974-12-17 | Eastman Kodak Co | Synthesis of indolininium methine dyes |
| US4054583A (en) * | 1976-07-06 | 1977-10-18 | Eli Lilly And Company | Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one |
| WO1997004774A1 (en) * | 1995-08-02 | 1997-02-13 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
| US6030970A (en) * | 1995-08-02 | 2000-02-29 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
| JP2000504013A (ja) * | 1996-02-01 | 2000-04-04 | スミスクライン・ビーチャム・コーポレイション | エンドセリンレセプターアンタゴニスト |
| US6174906B1 (en) | 1999-10-01 | 2001-01-16 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
-
1968
- 1968-11-22 US US778314A patent/US3700661A/en not_active Expired - Lifetime
-
1969
- 1969-11-12 CH CH1679469A patent/CH529774A/de not_active IP Right Cessation
- 1969-11-12 CH CH350272A patent/CH537938A/de not_active IP Right Cessation
- 1969-11-12 CH CH350372A patent/CH537942A/de not_active IP Right Cessation
- 1969-11-14 CH CH217372A patent/CH567490A5/xx not_active IP Right Cessation
- 1969-11-14 CH CH1695669A patent/CH561192A5/xx not_active IP Right Cessation
- 1969-11-14 CA CA067476A patent/CA918669A/en not_active Expired
- 1969-11-14 CH CH217272A patent/CH567489A5/xx not_active IP Right Cessation
- 1969-11-14 CH CH217472A patent/CH568314A5/xx not_active IP Right Cessation
- 1969-11-17 IL IL33369A patent/IL33369A/en unknown
- 1969-11-18 CH CH1710469A patent/CH567523A5/xx not_active IP Right Cessation
- 1969-11-18 CH CH107372A patent/CH578547A5/xx not_active IP Right Cessation
- 1969-11-19 CH CH1719469A patent/CH574890A5/xx not_active IP Right Cessation
- 1969-11-20 GB GB28139/71A patent/GB1298218A/en not_active Expired
- 1969-11-20 DK DK617169AA patent/DK130117B/da unknown
- 1969-11-20 GB GB56792/69A patent/GB1298213A/en not_active Expired
- 1969-11-20 GB GB00793/71A patent/GB1298216A/en not_active Expired
- 1969-11-20 GB GB00792/71A patent/GB1298215A/en not_active Expired
- 1969-11-20 NL NL6917499A patent/NL6917499A/xx unknown
- 1969-11-20 GB GB56791/69A patent/GB1298212A/en not_active Expired
- 1969-11-20 DK DK617269AA patent/DK129090B/da unknown
- 1969-11-20 GB GB56790/69A patent/GB1298211A/en not_active Expired
- 1969-11-20 CA CA067,962A patent/CA944770A/en not_active Expired
- 1969-11-20 GB GB28138/71A patent/GB1298217A/en not_active Expired
- 1969-11-20 GB GB28140/71A patent/GB1298219A/en not_active Expired
- 1969-11-20 GB GB56793/63A patent/GB1298214A/en not_active Expired
- 1969-11-21 NO NO4629/69A patent/NO133806C/no unknown
- 1969-11-21 FR FR6940173A patent/FR2024920A1/fr not_active Withdrawn
- 1969-11-21 AT AT1089069A patent/AT294331B/de not_active IP Right Cessation
- 1969-11-21 SE SE7209181A patent/SE376422B/xx unknown
- 1969-11-21 SE SE16038/69A patent/SE355801B/xx unknown
- 1969-11-21 AT AT877270A patent/AT299463B/de not_active IP Right Cessation
- 1969-11-21 BR BR214374/69A patent/BR6914374D0/pt unknown
- 1969-11-21 NL NL6917554A patent/NL6917554A/xx unknown
- 1969-11-21 FR FR6940172A patent/FR2030078A1/fr not_active Withdrawn
- 1969-11-21 FR FR6940170A patent/FR2024918A1/fr not_active Withdrawn
- 1969-11-21 ES ES373753A patent/ES373753A1/es not_active Expired
- 1969-11-21 FR FR6940171A patent/FR2024919A1/fr not_active Withdrawn
- 1969-11-21 NL NL6917557A patent/NL6917557A/xx not_active Application Discontinuation
- 1969-11-21 AT AT464671A patent/AT308981B/de active
- 1969-11-21 BR BR214373/69A patent/BR6914373D0/pt unknown
- 1969-11-21 AT AT1089169A patent/AT304772B/de not_active IP Right Cessation
- 1969-11-21 ES ES373752A patent/ES373752A1/es not_active Expired
- 1969-11-21 SE SE16036/69A patent/SE364715B/xx unknown
- 1969-11-21 NL NL6917574A patent/NL6917574A/xx unknown
- 1969-11-21 BR BR214375/69A patent/BR6914375D0/pt unknown
- 1969-11-21 DE DE19691958601 patent/DE1958601A1/de active Pending
- 1969-11-21 AT AT899970A patent/AT294832B/de not_active IP Right Cessation
- 1969-11-21 ES ES373751A patent/ES373751A1/es not_active Expired
- 1969-11-21 FI FI693380A patent/FI47572C/fi active
- 1969-11-21 SE SE16039/69A patent/SE354657B/xx unknown
- 1969-11-21 IE IE1575/69A patent/IE33651B1/xx unknown
- 1969-11-21 AT AT1088969A patent/AT292694B/de not_active IP Right Cessation
- 1969-11-21 SE SE16037/69A patent/SE361887B/xx unknown
- 1969-11-21 BR BR214372/69A patent/BR6914372D0/pt unknown
- 1969-11-21 DE DE1958600A patent/DE1958600C3/de not_active Expired
- 1969-11-21 AT AT1089269A patent/AT295757B/de not_active IP Right Cessation
- 1969-11-21 DE DE19691958608 patent/DE1958608A1/de active Pending
- 1969-11-21 AT AT877370A patent/AT292695B/de not_active IP Right Cessation
- 1969-11-22 JP JP44093897A patent/JPS5022031B1/ja active Pending
- 1969-11-22 ES ES373754A patent/ES373754A1/es not_active Expired
- 1969-11-24 BE BE742087D patent/BE742087A/xx unknown
- 1969-11-24 BE BE742090D patent/BE742090A/xx unknown
- 1969-11-24 BE BE742089D patent/BE742089A/xx unknown
- 1969-11-24 BE BE742088D patent/BE742088A/xx unknown
-
1971
- 1971-08-12 DK DK394671AA patent/DK126655B/da unknown
-
1972
- 1972-02-04 DK DK50772AA patent/DK127975B/da unknown
- 1972-04-21 ES ES401968A patent/ES401968A1/es not_active Expired
-
1973
- 1973-05-28 IL IL42366A patent/IL42366A0/xx unknown
- 1973-08-27 PH PH14968A patent/PH11342A/en unknown
- 1973-08-27 PH PH14967A patent/PH10667A/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |