ES398210A1 - Un procedimiento para preparar compuestos de acil-xilidida. - Google Patents
Un procedimiento para preparar compuestos de acil-xilidida.Info
- Publication number
- ES398210A1 ES398210A1 ES398210A ES398210A ES398210A1 ES 398210 A1 ES398210 A1 ES 398210A1 ES 398210 A ES398210 A ES 398210A ES 398210 A ES398210 A ES 398210A ES 398210 A1 ES398210 A1 ES 398210A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- propyl
- reacted
- butyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960005015 local anesthetics Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/38—Acyl halides
- C07C53/46—Acyl halides containing halogen outside the carbonyl halide group
- C07C53/50—Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10077770A | 1970-12-22 | 1970-12-22 | |
| US00164022A US3812147A (en) | 1970-12-22 | 1971-07-19 | Acylxylidide local anaesthetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES398210A1 true ES398210A1 (es) | 1975-03-16 |
Family
ID=26797539
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES398210A Expired ES398210A1 (es) | 1970-12-22 | 1971-12-21 | Un procedimiento para preparar compuestos de acil-xilidida. |
| ES425626A Expired ES425626A1 (es) | 1970-12-22 | 1974-04-24 | Un procedimiento para preparar compuestos de acil-xilidida. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES425626A Expired ES425626A1 (es) | 1970-12-22 | 1974-04-24 | Un procedimiento para preparar compuestos de acil-xilidida. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US3812147A (en, 2012) |
| JP (1) | JPS5644063B1 (en, 2012) |
| AR (1) | AR193840A1 (en, 2012) |
| AT (1) | AT319205B (en, 2012) |
| AU (1) | AU468489B2 (en, 2012) |
| BE (1) | BE776656A (en, 2012) |
| BR (1) | BR7108466D0 (en, 2012) |
| CA (1) | CA943966A (en, 2012) |
| DD (1) | DD99779A5 (en, 2012) |
| DE (1) | DE2162744C3 (en, 2012) |
| DK (1) | DK139814B (en, 2012) |
| ES (2) | ES398210A1 (en, 2012) |
| FI (1) | FI55027C (en, 2012) |
| FR (1) | FR2118985B1 (en, 2012) |
| GB (1) | GB1369259A (en, 2012) |
| HU (1) | HU163373B (en, 2012) |
| IE (1) | IE35909B1 (en, 2012) |
| IT (1) | IT1066334B (en, 2012) |
| NL (2) | NL172149C (en, 2012) |
| NO (1) | NO135934C (en, 2012) |
| PL (1) | PL83097B1 (en, 2012) |
| SE (1) | SE393374B (en, 2012) |
| SU (1) | SU419023A3 (en, 2012) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4237068A (en) * | 1971-07-28 | 1980-12-02 | Astra Pharmaceutical Products, Inc. | Primary aminoacylanilides |
| US3957996A (en) * | 1971-12-08 | 1976-05-18 | Astra Pharmaceutical Products, Inc. | Pharmaceutical local anesthetic compositions |
| US3966934A (en) * | 1971-12-08 | 1976-06-29 | Astra Pharmaceutical Products, Inc. | Synergistic local anesthetic compositions |
| US3975443A (en) * | 1972-06-06 | 1976-08-17 | Allen & Hanburys Limited | 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine |
| JPS598269B2 (ja) * | 1975-08-22 | 1984-02-23 | 萬有製薬株式会社 | オメガ − アミノアルカンサンアリ−ルアミドノ セイホウ |
| JPS57176939A (en) * | 1981-04-03 | 1982-10-30 | Goodrich Co B F | Improved synthesis of hindered amine stabilizer for high polymer materials |
| US4891058A (en) * | 1988-07-18 | 1990-01-02 | Ici Americas Inc. | 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use |
| SE8900685D0 (sv) * | 1989-02-28 | 1989-02-28 | Astra Ab | New compounds |
| US5153226A (en) * | 1989-08-31 | 1992-10-06 | Warner-Lambert Company | Acat inhibitors for treating hypocholesterolemia |
| JP2010510227A (ja) | 2006-11-20 | 2010-04-02 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 痛みおよび痒みの治療方法、組成物およびキット |
| EP2451944A4 (en) | 2009-07-10 | 2012-11-28 | Harvard College | PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI-INFLAMMATORY AGENTS |
| JP6833811B2 (ja) | 2015-08-03 | 2021-02-24 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 荷電イオンチャネル遮断薬及び使用方法 |
| US10934263B2 (en) | 2019-03-11 | 2021-03-02 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10968179B2 (en) | 2019-03-11 | 2021-04-06 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10786485B1 (en) | 2019-03-11 | 2020-09-29 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| KR20210145164A (ko) | 2019-03-11 | 2021-12-01 | 녹시온 테라퓨틱스 인코포레이티드 | 에스테르 치환된 이온 채널 차단제 및 사용 방법 |
| BR112022008575A2 (pt) | 2019-11-06 | 2022-08-09 | Nocion Therapeutics Inc | Bloqueadores de canal iônico carregado e métodos para uso |
| EP4054586A4 (en) | 2019-11-06 | 2023-11-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CN119118953A (zh) | 2020-03-11 | 2024-12-13 | 诺西恩医疗公司 | 带电的离子通道阻滞剂及其使用方法 |
| US12162851B2 (en) | 2020-03-11 | 2024-12-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1124837A (en) * | 1966-06-03 | 1968-08-21 | Wyeth John & Brother Ltd | Substituted anilides |
-
1971
- 1971-07-19 US US00164022A patent/US3812147A/en not_active Expired - Lifetime
- 1971-12-07 SE SE7115656A patent/SE393374B/xx unknown
- 1971-12-14 BE BE776656A patent/BE776656A/xx not_active IP Right Cessation
- 1971-12-15 SU SU1726195A patent/SU419023A3/ru active
- 1971-12-16 HU HUAA690A patent/HU163373B/hu unknown
- 1971-12-17 DK DK619771AA patent/DK139814B/da not_active IP Right Cessation
- 1971-12-17 NO NO4669/71A patent/NO135934C/no unknown
- 1971-12-17 DE DE2162744A patent/DE2162744C3/de not_active Expired
- 1971-12-18 IT IT54845/71A patent/IT1066334B/it active
- 1971-12-20 AU AU37099/71A patent/AU468489B2/en not_active Expired
- 1971-12-20 AT AT1089671A patent/AT319205B/de not_active IP Right Cessation
- 1971-12-20 IE IE1609/71A patent/IE35909B1/xx unknown
- 1971-12-21 AR AR239721A patent/AR193840A1/es active
- 1971-12-21 CA CA130,662A patent/CA943966A/en not_active Expired
- 1971-12-21 GB GB5937771A patent/GB1369259A/en not_active Expired
- 1971-12-21 BR BR8466/71A patent/BR7108466D0/pt unknown
- 1971-12-21 PL PL1971152331A patent/PL83097B1/pl unknown
- 1971-12-21 DD DD159785A patent/DD99779A5/xx unknown
- 1971-12-21 ES ES398210A patent/ES398210A1/es not_active Expired
- 1971-12-21 FR FR7145983A patent/FR2118985B1/fr not_active Expired
- 1971-12-22 FI FI3658/71A patent/FI55027C/fi active
- 1971-12-22 JP JP10453571A patent/JPS5644063B1/ja active Pending
- 1971-12-22 NL NLAANVRAGE7117644,A patent/NL172149C/xx not_active IP Right Cessation
-
1974
- 1974-04-24 ES ES425626A patent/ES425626A1/es not_active Expired
-
1982
- 1982-10-26 NL NL8204126A patent/NL8204126A/nl not_active Application Discontinuation
Also Published As
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