ES396132A1 - Proceso de preparacion de los complejos del acido metafos- forico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcali-metalicas de los mismos. - Google Patents
Proceso de preparacion de los complejos del acido metafos- forico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcali-metalicas de los mismos.Info
- Publication number
- ES396132A1 ES396132A1 ES396132A ES396132A ES396132A1 ES 396132 A1 ES396132 A1 ES 396132A1 ES 396132 A ES396132 A ES 396132A ES 396132 A ES396132 A ES 396132A ES 396132 A1 ES396132 A1 ES 396132A1
- Authority
- ES
- Spain
- Prior art keywords
- deoxy
- c22h24n2o8
- hpo3
- compounds
- complexes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- SGKRLCUYIXIAHR-AKNGSSGZSA-N (4s,4ar,5s,5ar,6r,12ar)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1=CC=C2[C@H](C)[C@@H]([C@H](O)[C@@H]3[C@](C(O)=C(C(N)=O)C(=O)[C@H]3N(C)C)(O)C3=O)C3=C(O)C2=C1O SGKRLCUYIXIAHR-AKNGSSGZSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- UEZVMMHDMIWARA-UHFFFAOYSA-N Metaphosphoric acid Chemical compound OP(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-N 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 229920000388 Polyphosphate Polymers 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000001205 polyphosphate Substances 0.000 abstract 1
- 235000011176 polyphosphates Nutrition 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT5470870 | 1970-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES396132A1 true ES396132A1 (es) | 1972-12-01 |
Family
ID=20081722
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES396132A Expired ES396132A1 (es) | 1970-10-30 | 1971-10-19 | Proceso de preparacion de los complejos del acido metafos- forico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcali-metalicas de los mismos. |
| ES427715A Expired ES427715A2 (es) | 1970-10-30 | 1974-06-27 | Proceso de preparacion de los complejos del acido metafosfo-rico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcalimetalicas de los mismos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES427715A Expired ES427715A2 (es) | 1970-10-30 | 1974-06-27 | Proceso de preparacion de los complejos del acido metafosfo-rico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcalimetalicas de los mismos. |
Country Status (18)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES396132A1 (es) * | 1970-10-30 | 1972-12-01 | Villax | Proceso de preparacion de los complejos del acido metafos- forico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcali-metalicas de los mismos. |
| GB1350196A (en) * | 1972-10-26 | 1974-04-18 | Pfizer | Doxycyline parenteral composition |
| PT72107B (fr) * | 1980-11-25 | 1981-10-28 | Joao Emerico Villax | Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium |
| CN114276271A (zh) * | 2021-11-22 | 2022-04-05 | 新乡医学院三全学院 | 一种制备不同颗粒度盐酸多西环素固体粉末的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1068701B (de) * | 1959-11-12 | Bristol Laboratories Inc., East Syracuse, N. Y. (V. St. A.) | Verfahren zur Herstellung von antibiotisch wirksamem Tetracyclinnatriumhexametaphosphat | |
| US3068264A (en) * | 1961-06-06 | 1962-12-11 | American Cyanamid Co | Tetracycline antibiotic-aluminumphosphoric acid complexes |
| ES396132A1 (es) * | 1970-10-30 | 1972-12-01 | Villax | Proceso de preparacion de los complejos del acido metafos- forico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcali-metalicas de los mismos. |
-
1971
- 1971-10-19 ES ES396132A patent/ES396132A1/es not_active Expired
- 1971-10-21 DE DE19712152476 patent/DE2152476A1/de active Pending
- 1971-10-25 DK DK516671A patent/DK152118C/da not_active IP Right Cessation
- 1971-10-26 IL IL38014A patent/IL38014A/xx unknown
- 1971-10-26 CH CH1558071A patent/CH593239A5/xx not_active IP Right Cessation
- 1971-10-26 NL NL717114749A patent/NL152248B/xx not_active IP Right Cessation
- 1971-10-26 SE SE7113551A patent/SE380518B/xx unknown
- 1971-10-27 NO NO3985/71A patent/NO140718C/no unknown
- 1971-10-27 FI FI3060/71A patent/FI54799C/fi active
- 1971-10-27 CA CA126,250A patent/CA988081A/en not_active Expired
- 1971-10-28 FR FR7138787A patent/FR2111952B1/fr not_active Expired
- 1971-10-28 ZA ZA717214A patent/ZA717214B/xx unknown
- 1971-10-29 BE BE774717A patent/BE774717A/xx not_active IP Right Cessation
- 1971-10-30 JP JP8671171A patent/JPS5510576B1/ja active Pending
- 1971-11-01 AU AU35209/71A patent/AU473909B2/en not_active Expired
- 1971-11-02 AT AT09439/71A patent/AT312166B/de not_active IP Right Cessation
-
1974
- 1974-06-24 DK DK337274A patent/DK152119C/da not_active IP Right Cessation
- 1974-06-24 FI FI1919/74A patent/FI59789C/fi active
- 1974-06-26 AU AU70520/74A patent/AU497158B2/en not_active Expired
- 1974-06-26 DE DE2430550A patent/DE2430550C2/de not_active Expired
- 1974-06-27 ES ES427715A patent/ES427715A2/es not_active Expired
- 1974-06-28 BE BE146061A patent/BE817063R/xx active
- 1974-06-28 GB GB2877374A patent/GB1463726A/en not_active Expired
- 1974-06-28 AT AT540074A patent/AT332970B/de not_active IP Right Cessation
- 1974-06-28 CH CH895274A patent/CH611875A5/xx not_active IP Right Cessation
- 1974-06-28 CA CA203,732A patent/CA1014552A/en not_active Expired
- 1974-06-28 IL IL45146A patent/IL45146A/en unknown
- 1974-06-28 ZA ZA00744181A patent/ZA744181B/xx unknown
- 1974-06-28 FR FR7422640A patent/FR2282865A2/fr active Granted
- 1974-07-01 NL NL7408875A patent/NL7408875A/xx not_active Application Discontinuation
- 1974-07-01 JP JP49075255A patent/JPS5745215B2/ja not_active Expired
- 1974-07-01 SE SE7408685A patent/SE389333B/xx not_active IP Right Cessation
-
1979
- 1979-11-15 HK HK790/79A patent/HK79079A/xx unknown
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