PT72107B - Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium - Google Patents

Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium

Info

Publication number
PT72107B
PT72107B PT72107A PT7210780A PT72107B PT 72107 B PT72107 B PT 72107B PT 72107 A PT72107 A PT 72107A PT 7210780 A PT7210780 A PT 7210780A PT 72107 B PT72107 B PT 72107B
Authority
PT
Portugal
Prior art keywords
hydroxitetracycline
desodium
dioxi
tetrametaphosphate
alpha
Prior art date
Application number
PT72107A
Other languages
English (en)
Portuguese (pt)
Other versions
PT72107A (fr
Original Assignee
Joao Emerico Villax
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to PT72107A priority Critical patent/PT72107B/fr
Application filed by Joao Emerico Villax filed Critical Joao Emerico Villax
Publication of PT72107A publication Critical patent/PT72107A/fr
Publication of PT72107B publication Critical patent/PT72107B/fr
Priority to ZA817804A priority patent/ZA817804B/xx
Priority to AU77612/81A priority patent/AU543041B2/en
Priority to KR1019810004468A priority patent/KR860000450B1/ko
Priority to ES507293A priority patent/ES8302629A1/es
Priority to PH26527A priority patent/PH20236A/en
Priority to DE19813146279 priority patent/DE3146279A1/de
Priority to FR8121887A priority patent/FR2494685A1/fr
Priority to NLAANVRAGE8105309,A priority patent/NL190067C/xx
Priority to BE0/206644A priority patent/BE891236A/fr
Priority to JP56187068A priority patent/JPS57116033A/ja
Priority to GB8135611A priority patent/GB2088864B/en
Priority to HK106/87A priority patent/HK10687A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04—Sodium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT72107A 1980-11-25 1980-11-25 Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium PT72107B (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
PT72107A PT72107B (fr) 1980-11-25 1980-11-25 Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium
ZA817804A ZA817804B (en) 1980-11-25 1981-11-11 Process for the preparation of a water soluble complex of alpha-6-deoxy-5-hydroxytetracycline and of sodium tetrametaphosphate
AU77612/81A AU543041B2 (en) 1980-11-25 1981-11-18 Alpha-6-deoxy-5-hydroxytetracycline sodium tetrameta- phosphate complex
KR1019810004468A KR860000450B1 (ko) 1980-11-25 1981-11-19 α-6-데옥씨-5-하이드록씨 테트라 싸이클린과 소듐 테트라메타포스 페이트의 수용성 복합체의 제조방법
ES507293A ES8302629A1 (es) 1980-11-25 1981-11-19 Proceso de preparacion de un complejo soluble en agua de al-fa-6-desoxi-5-hidroxitetraciclina y sodio tetrametafosfato.
PH26527A PH20236A (en) 1980-11-25 1981-11-20 Process of oreoaration of a water soluble complex of 0(-6-deoxy-5-hydroxytetracyline and sodium tetrametaphoshate
DE19813146279 DE3146279A1 (de) 1980-11-25 1981-11-21 Verfahren zur herstellung eines wasserloeslichen komplexes aus (alpha)-6-desoxy-5-hydroxytetracyclin und natriumtetrametaphosphat
FR8121887A FR2494685A1 (fr) 1980-11-25 1981-11-23 Complexes d'a-6-desoxy-5-hydroxytetracycline et de tetrametaphosphate de sodium solubles dans l'eau, leur preparation et leur utilisation
JP56187068A JPS57116033A (en) 1980-11-25 1981-11-24 Lower alcohol-water solvation of sodium tetrametaphosphate complex of alpha-6-deoxy- hydroxytetracycline and manufacture
BE0/206644A BE891236A (fr) 1980-11-25 1981-11-24 Complexes d'alpha-6-desoxy-5-hydroxytetracycline et de tetrametaphosphate de sodium solubles dans l'eau, leur preparation et leur utilisation
NLAANVRAGE8105309,A NL190067C (nl) 1980-11-25 1981-11-24 Werkwijze voor de bereiding van een in water oplosbaar complex van alfa-6-deoxy-5-hydroxytetracycline en natriumtetrametafosfaat.
GB8135611A GB2088864B (en) 1980-11-25 1981-11-25 Doxycycline monosodium tetrametaphosphate complexes and their preparation
HK106/87A HK10687A (en) 1980-11-25 1987-01-28 Doxycycline monosodium tetrametaphosphate complexes and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT72107A PT72107B (fr) 1980-11-25 1980-11-25 Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium

Publications (2)

Publication Number Publication Date
PT72107A PT72107A (fr) 1980-12-01
PT72107B true PT72107B (fr) 1981-10-28

Family

ID=20082809

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72107A PT72107B (fr) 1980-11-25 1980-11-25 Procede de preparation d'un complexe hydrosoluble de alpha-6-dioxi-5-hydroxitetracycline et de tetrametaphosphate desodium

Country Status (13)

Country Link
JP (1) JPS57116033A (fr)
KR (1) KR860000450B1 (fr)
AU (1) AU543041B2 (fr)
BE (1) BE891236A (fr)
DE (1) DE3146279A1 (fr)
ES (1) ES8302629A1 (fr)
FR (1) FR2494685A1 (fr)
GB (1) GB2088864B (fr)
HK (1) HK10687A (fr)
NL (1) NL190067C (fr)
PH (1) PH20236A (fr)
PT (1) PT72107B (fr)
ZA (1) ZA817804B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5538954A (en) * 1994-06-24 1996-07-23 A/S Dumex (Dumex Ltd.) Salts of tetracyclines
NZ544826A (en) 2003-07-25 2008-07-31 Warner Chilcott Co Inc A doxycycline metal complex in a solid dosage form

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE568762A (fr) *
DE1068701B (de) * 1959-11-12 Bristol Laboratories Inc., East Syracuse, N. Y. (V. St. A.) Verfahren zur Herstellung von antibiotisch wirksamem Tetracyclinnatriumhexametaphosphat
US2791609A (en) * 1956-09-27 1957-05-07 Murray A Kaplan Tetracycline metallo-phosphate complexes and method preparation
US2795528A (en) * 1956-10-24 1957-06-11 Frank H Buckwalter Therapeutic composition containing a tetracycline and a phosphate other than orthophosphate
US3053892A (en) * 1960-04-27 1962-09-11 American Cyanamid Co Metaphosphoric acid complexes of tetracycline and its analogs
US3068264A (en) * 1961-06-06 1962-12-11 American Cyanamid Co Tetracycline antibiotic-aluminumphosphoric acid complexes
GB1180701A (en) * 1967-06-23 1970-02-11 Pfizer & Co C Process for Purifying Tetracycline Antibiotics with Phosphate Salts
ES396132A1 (es) * 1970-10-30 1972-12-01 Villax Proceso de preparacion de los complejos del acido metafos- forico de la alfa-6-deoxi-5-hidroxitetraciclina y las sales alcali-metalicas de los mismos.
JPS5745215A (en) * 1980-09-01 1982-03-15 Toshiba Corp Molding device of iron plate for wound core

Also Published As

Publication number Publication date
FR2494685A1 (fr) 1982-05-28
AU543041B2 (en) 1985-03-28
FR2494685B1 (fr) 1985-02-01
NL190067B (nl) 1993-05-17
NL190067C (nl) 1993-10-18
PH20236A (en) 1986-11-10
JPS57116033A (en) 1982-07-19
ES507293A0 (es) 1983-02-01
BE891236A (fr) 1982-05-24
GB2088864A (en) 1982-06-16
DE3146279A1 (de) 1982-08-19
AU7761281A (en) 1982-06-03
ZA817804B (en) 1982-12-29
ES8302629A1 (es) 1983-02-01
NL8105309A (nl) 1982-06-16
KR860000450B1 (ko) 1986-04-26
PT72107A (fr) 1980-12-01
KR830007076A (ko) 1983-10-14
HK10687A (en) 1987-02-06
GB2088864B (en) 1984-09-12

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