ES391792A1 - Procedure for the preparation of bencenosulfonilureas. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of bencenosulfonilureas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES391792A1
ES391792A1 ES391792A ES391792A ES391792A1 ES 391792 A1 ES391792 A1 ES 391792A1 ES 391792 A ES391792 A ES 391792A ES 391792 A ES391792 A ES 391792A ES 391792 A1 ES391792 A1 ES 391792A1
Authority
ES
Spain
Prior art keywords
carbon atoms
radical
formula
optionally
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES391792A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702027950 external-priority patent/DE2027950A1/en
Priority claimed from DE19712120266 external-priority patent/DE2120266A1/en
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of ES391792A1 publication Critical patent/ES391792A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for the preparation of benzenesulfonylureas of the formula **(See formula)** in which: X signifies hydrogen, chlorine, bromine, methoxy or methyl; Y means -CH (CH3) -CH2-, -CH2-CH (CH3) - or preferably -CH2-CH2; R means a) alcohol with 3 to t carbon atoms, b) cycloalcohyl with 5 to 8 carbon atoms which may optionally be substituted by 1 or 2 alcohol groups with a total of 3 carbon atoms or by chlorine, c) cycloalkenyl with 5 to 8 carbon atoms, which may optionally be replaced by a total of 3 carbon atoms, d) bicycloalkoxy or bicycloalkenyl with 7 or 8 carbon atoms, e) nortricicycl, f) spiro [2,4] -heptyl, g) an alkylene-imino radical with 3 to 7 carbon atoms in the ring that can be optionally saturated or substituted by 1 or 2 methyl groups or a lower alcohol group or a methoxy group, h) a pentamethylene imino radical substituted by an endoalkylene radical with 1 to 3 carbon atoms, i) a hexamethylene radical substituted by an endoethylene group in beta-epsilon position, k) a tetrahydro-isoindoline, 4,7-endoalkylene-hexahydro- or tetrahydro-isoindoline radical, in which the endoalkylene group contains 1 or 2 carbon atoms and the double bond of the tetrahydro compound is in position 5, 6. Z means hydrogen or a hydrocarbon radical with 1 or 2 carbon atoms that forms with Y a 5- or 6-membered ring, and its salts, characterized in that it is introduced into compounds containing group I of the formula **(See formula)** where n means the name 0, 1 or 2, a radical II of the formula **(See formula)** and a radical III of the formula **(See formula)** optionally in a stepwise manner, in which the radicals I and III are linked by means of a NH-group contained in I or III, the products according to the invention are optionally oxidized and these products are subsequently treated optionally for the formation of salts with alkaline or acidic agents physiologically acceptable inorganic or organic. (Machine-translation by Google Translate, not legally binding)
ES391792A 1970-06-06 1971-05-31 Procedure for the preparation of bencenosulfonilureas. (Machine-translation by Google Translate, not legally binding) Expired ES391792A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19702027950 DE2027950A1 (en) 1970-06-06 1970-06-06 Benzenesulfonylureas and process for their preparation
DE19712120266 DE2120266A1 (en) 1971-04-26 1971-04-26 Benzenesulfonyl semicarbazides and processes for their preparation

Publications (1)

Publication Number Publication Date
ES391792A1 true ES391792A1 (en) 1974-08-01

Family

ID=25759238

Family Applications (3)

Application Number Title Priority Date Filing Date
ES391792A Expired ES391792A1 (en) 1970-06-06 1971-05-31 Procedure for the preparation of bencenosulfonilureas. (Machine-translation by Google Translate, not legally binding)
ES418120A Expired ES418120A1 (en) 1970-06-06 1973-08-22 Procedure for the preparation of sulfonil-ureas. (Machine-translation by Google Translate, not legally binding)
ES444834A Expired ES444834A1 (en) 1970-06-06 1976-01-31 Procedure for the preparation of semicarbazides. (Machine-translation by Google Translate, not legally binding)

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES418120A Expired ES418120A1 (en) 1970-06-06 1973-08-22 Procedure for the preparation of sulfonil-ureas. (Machine-translation by Google Translate, not legally binding)
ES444834A Expired ES444834A1 (en) 1970-06-06 1976-01-31 Procedure for the preparation of semicarbazides. (Machine-translation by Google Translate, not legally binding)

Country Status (15)

Country Link
BE (1) BE768135A (en)
BG (1) BG19796A3 (en)
CA (1) CA986114A (en)
CH (12) CH586203A5 (en)
DK (1) DK138793C (en)
ES (3) ES391792A1 (en)
FI (1) FI50792C (en)
FR (1) FR2100731A1 (en)
HU (1) HU166708B (en)
IE (1) IE35332B1 (en)
IL (1) IL36983A (en)
IT (1) IT1037032B (en)
NL (1) NL7107502A (en)
RO (1) RO58731A (en)
SE (1) SE361038B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1294957B (en) * 1966-07-02 1969-05-14 Boehringer & Soehne Gmbh Process for the preparation of hydrindene sulphonylureas and sulphonyl semicarbazides

Also Published As

Publication number Publication date
FR2100731A1 (en) 1972-03-24
HU166708B (en) 1975-05-28
DK138793C (en) 1979-03-26
FR2100731B1 (en) 1974-09-06
SE361038B (en) 1973-10-15
ES418120A1 (en) 1976-09-01
RO58731A (en) 1975-12-15
CH568291A5 (en) 1975-10-31
CH580593A5 (en) 1976-10-15
CH586219A5 (en) 1977-03-31
IE35332L (en) 1971-12-06
ES444834A1 (en) 1977-05-01
CH576973A5 (en) 1976-06-30
CH577498A5 (en) 1976-07-15
CH586203A5 (en) 1977-03-31
IL36983A (en) 1976-03-31
NL7107502A (en) 1971-12-08
CH577478A5 (en) 1976-07-15
CH576965A5 (en) 1976-06-30
BG19796A3 (en) 1975-10-10
FI50792C (en) 1976-07-12
BE768135A (en) 1971-12-06
IE35332B1 (en) 1976-01-21
DK138793B (en) 1978-10-30
CH577479A5 (en) 1976-07-15
CA986114A (en) 1976-03-23
CH577974A5 (en) 1976-07-30
FI50792B (en) 1976-03-31
IT1037032B (en) 1979-11-10
IL36983A0 (en) 1971-08-25
CH576972A5 (en) 1976-06-30
CH576971A5 (en) 1976-06-30

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