ES448000A1 - 2,3-methylene prostaglandins and their preparation - Google Patents

2,3-methylene prostaglandins and their preparation

Info

Publication number
ES448000A1
ES448000A1 ES448000A ES448000A ES448000A1 ES 448000 A1 ES448000 A1 ES 448000A1 ES 448000 A ES448000 A ES 448000A ES 448000 A ES448000 A ES 448000A ES 448000 A1 ES448000 A1 ES 448000A1
Authority
ES
Spain
Prior art keywords
formula
prostaglandins
methylene
preparation
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES448000A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH995973A external-priority patent/CH599147A5/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES448000A1 publication Critical patent/ES448000A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the production of cyclopropane derivatives of formula Ic, ** (See formula) ** wherein R1 is alkyl, cycloalkyl, or aralkyl, and D is one of the four carbocycles of formulas IIa, IIb, IIc or IId, ** (See formula) ** R2 and R3 are independently hydrogen or C 1-4 -alkyl, characterized in that a compound of formula Id is esterified, ** (See formula) ** where R1 is hydrogen, and R2, R3 and D have the meanings indicated above. (Machine-translation by Google Translate, not legally binding)
ES448000A 1973-07-09 1976-05-17 2,3-methylene prostaglandins and their preparation Expired ES448000A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH995973A CH599147A5 (en) 1973-07-09 1973-07-09 Long-acting synthetic prostaglandins
CH604974 1974-05-04

Publications (1)

Publication Number Publication Date
ES448000A1 true ES448000A1 (en) 1977-11-01

Family

ID=25698889

Family Applications (2)

Application Number Title Priority Date Filing Date
ES74428063A Expired ES428063A1 (en) 1973-07-09 1974-07-08 2,3-methylene prostaglandins and their preparation
ES448000A Expired ES448000A1 (en) 1973-07-09 1976-05-17 2,3-methylene prostaglandins and their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES74428063A Expired ES428063A1 (en) 1973-07-09 1974-07-08 2,3-methylene prostaglandins and their preparation

Country Status (15)

Country Link
JP (1) JPS5040549A (en)
AT (1) AT355233B (en)
CA (1) CA1050976A (en)
DD (1) DD113348A5 (en)
DE (1) DE2431930A1 (en)
DK (1) DK142143B (en)
ES (2) ES428063A1 (en)
FI (1) FI58117C (en)
FR (2) FR2236490B1 (en)
GB (2) GB1479964A (en)
IE (1) IE41342B1 (en)
IL (1) IL45215A (en)
NL (1) NL7409119A (en)
NO (1) NO742378L (en)
SE (2) SE7408689L (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2638401A1 (en) * 1975-09-05 1977-03-17 Sandoz Ag NEW PROSTAGLANDIN, THEIR USE AND MANUFACTURING
JPS52116930U (en) * 1976-03-03 1977-09-05
JPS55147056U (en) * 1979-04-06 1980-10-22
US4431669A (en) * 1982-12-17 1984-02-14 Schering Corporation Cyclopropyl substituted polyenes
JPH04204679A (en) * 1990-11-30 1992-07-27 Fuji Photo Film Co Ltd Electrophotographic image recorder

Also Published As

Publication number Publication date
DK142143B (en) 1980-09-08
DE2431930A1 (en) 1975-01-30
SE7512194L (en) 1975-10-30
DK142143C (en) 1981-02-09
IE41342L (en) 1975-01-09
FR2318169A1 (en) 1977-02-11
SE7408689L (en) 1975-01-10
IL45215A (en) 1977-07-31
FI201174A (en) 1975-01-10
CA1050976A (en) 1979-03-20
JPS5040549A (en) 1975-04-14
FI58117C (en) 1980-12-10
NL7409119A (en) 1975-01-13
IL45215A0 (en) 1975-02-10
ATA559874A (en) 1979-07-15
GB1479964A (en) 1977-07-13
FR2318169B1 (en) 1978-11-03
DK352974A (en) 1975-03-03
FR2236490A1 (en) 1975-02-07
GB1479965A (en) 1977-07-13
DD113348A5 (en) 1975-06-05
AT355233B (en) 1980-02-25
ES428063A1 (en) 1977-02-01
FR2236490B1 (en) 1978-07-21
IE41342B1 (en) 1979-12-05
NO742378L (en) 1975-02-03
FI58117B (en) 1980-08-29

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