ES405984A1 - Substituted isoindolines processes for their manufacture and preparations containing them - Google Patents

Substituted isoindolines processes for their manufacture and preparations containing them

Info

Publication number
ES405984A1
ES405984A1 ES405984A ES405984A ES405984A1 ES 405984 A1 ES405984 A1 ES 405984A1 ES 405984 A ES405984 A ES 405984A ES 405984 A ES405984 A ES 405984A ES 405984 A1 ES405984 A1 ES 405984A1
Authority
ES
Spain
Prior art keywords
formula
compound
see formula
above meanings
see
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES405984A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of ES405984A1 publication Critical patent/ES405984A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the preparation of basically substituted phenylisoindolines of the formula I **(See formula)** where X is hydrogen or halogen, Y is hydrogen, halogen, an alcohol group with 1 to 4 carbon atoms, or an alkoxy group with 1 to 4 carbon atoms, and A is an alcohol radical with 2 to 3 carbon atoms, and where R1 and R2 signify the same or different alcohol radicals with 1 to 4 carbon atoms, or where R1 and R2, together with the nitrogen atoms, signify a saturated 5- or 6-membered heterocyclic ring, which may eventually be interrupted by another nitrogen atom, possibly substituted by lower alcohol or hydroxyalkyl groups, characterized in that a) a compound of formula II is reacted **(See formula)** wherein A, Y, R1 and R2 have the above meanings, with a substituted orthoxylene of formula III **(See formula)** where X has the above meanings and Z means an ester radical capable of reacting, or b) a compound of formula IV is reacted **(See formula)** where X and Y have the above meanings, with a compound of formula V **(See formula)** where Z, A, R1 and R2 have the above meanings; or c) a compound of formula VI is reacted **(See formula)** where X, A, and Z have the above meanings, with an amine of the formula NHR1R2, or d) a compound of the formula VII is reduced **(See formula)** where X, Y, R1 and R2 have the above meanings and W represents one oxygen atom or two hydrogen atoms; or e) a compound of formula VIII is reduced **(See formula)** where X, W, Y, R1 and R2 have the previous meanings and A'means (see formula). (Machine-translation by Google Translate, not legally binding)
ES405984A 1971-08-25 1972-08-19 Substituted isoindolines processes for their manufacture and preparations containing them Expired ES405984A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2142563A DE2142563A1 (en) 1971-08-25 1971-08-25 SUBSTITUTED ISOINDOLINE AND PROCESS FOR THEIR PRODUCTION

Publications (1)

Publication Number Publication Date
ES405984A1 true ES405984A1 (en) 1976-02-01

Family

ID=5817747

Family Applications (1)

Application Number Title Priority Date Filing Date
ES405984A Expired ES405984A1 (en) 1971-08-25 1972-08-19 Substituted isoindolines processes for their manufacture and preparations containing them

Country Status (11)

Country Link
JP (1) JPS4832863A (en)
AT (1) AT324321B (en)
AU (1) AU4595072A (en)
BE (1) BE788032A (en)
DE (1) DE2142563A1 (en)
ES (1) ES405984A1 (en)
FR (1) FR2150828B1 (en)
GB (1) GB1383408A (en)
HU (1) HU165059B (en)
NL (1) NL7211327A (en)
ZA (1) ZA725836B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000383A1 (en) * 1977-12-13 1979-06-28 Fujitsu Ltd Thin-film coil producing method
EP1717235A3 (en) * 2005-04-29 2007-02-28 Bioprojet Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands

Also Published As

Publication number Publication date
HU165059B (en) 1974-06-28
FR2150828B1 (en) 1976-04-16
DE2142563A1 (en) 1973-05-03
AU4595072A (en) 1974-02-28
BE788032A (en) 1973-02-26
FR2150828A1 (en) 1973-04-13
JPS4832863A (en) 1973-05-02
GB1383408A (en) 1974-02-12
NL7211327A (en) 1973-02-27
AT324321B (en) 1975-08-25
ZA725836B (en) 1973-06-27

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