ES405984A1 - Substituted isoindolines processes for their manufacture and preparations containing them - Google Patents
Substituted isoindolines processes for their manufacture and preparations containing themInfo
- Publication number
- ES405984A1 ES405984A1 ES405984A ES405984A ES405984A1 ES 405984 A1 ES405984 A1 ES 405984A1 ES 405984 A ES405984 A ES 405984A ES 405984 A ES405984 A ES 405984A ES 405984 A1 ES405984 A1 ES 405984A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- see formula
- above meanings
- see
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of basically substituted phenylisoindolines of the formula I **(See formula)** where X is hydrogen or halogen, Y is hydrogen, halogen, an alcohol group with 1 to 4 carbon atoms, or an alkoxy group with 1 to 4 carbon atoms, and A is an alcohol radical with 2 to 3 carbon atoms, and where R1 and R2 signify the same or different alcohol radicals with 1 to 4 carbon atoms, or where R1 and R2, together with the nitrogen atoms, signify a saturated 5- or 6-membered heterocyclic ring, which may eventually be interrupted by another nitrogen atom, possibly substituted by lower alcohol or hydroxyalkyl groups, characterized in that a) a compound of formula II is reacted **(See formula)** wherein A, Y, R1 and R2 have the above meanings, with a substituted orthoxylene of formula III **(See formula)** where X has the above meanings and Z means an ester radical capable of reacting, or b) a compound of formula IV is reacted **(See formula)** where X and Y have the above meanings, with a compound of formula V **(See formula)** where Z, A, R1 and R2 have the above meanings; or c) a compound of formula VI is reacted **(See formula)** where X, A, and Z have the above meanings, with an amine of the formula NHR1R2, or d) a compound of the formula VII is reduced **(See formula)** where X, Y, R1 and R2 have the above meanings and W represents one oxygen atom or two hydrogen atoms; or e) a compound of formula VIII is reduced **(See formula)** where X, W, Y, R1 and R2 have the previous meanings and A'means (see formula). (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2142563A DE2142563A1 (en) | 1971-08-25 | 1971-08-25 | SUBSTITUTED ISOINDOLINE AND PROCESS FOR THEIR PRODUCTION |
Publications (1)
Publication Number | Publication Date |
---|---|
ES405984A1 true ES405984A1 (en) | 1976-02-01 |
Family
ID=5817747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES405984A Expired ES405984A1 (en) | 1971-08-25 | 1972-08-19 | Substituted isoindolines processes for their manufacture and preparations containing them |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS4832863A (en) |
AT (1) | AT324321B (en) |
AU (1) | AU4595072A (en) |
BE (1) | BE788032A (en) |
DE (1) | DE2142563A1 (en) |
ES (1) | ES405984A1 (en) |
FR (1) | FR2150828B1 (en) |
GB (1) | GB1383408A (en) |
HU (1) | HU165059B (en) |
NL (1) | NL7211327A (en) |
ZA (1) | ZA725836B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1979000383A1 (en) * | 1977-12-13 | 1979-06-28 | Fujitsu Ltd | Thin-film coil producing method |
EP1717235A3 (en) * | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
-
0
- BE BE788032D patent/BE788032A/en unknown
-
1971
- 1971-08-25 DE DE2142563A patent/DE2142563A1/en active Pending
-
1972
- 1972-08-18 NL NL7211327A patent/NL7211327A/xx unknown
- 1972-08-18 HU HUHO1509A patent/HU165059B/hu unknown
- 1972-08-19 ES ES405984A patent/ES405984A1/en not_active Expired
- 1972-08-23 FR FR7230017A patent/FR2150828B1/fr not_active Expired
- 1972-08-24 GB GB3950772A patent/GB1383408A/en not_active Expired
- 1972-08-24 AU AU45950/72A patent/AU4595072A/en not_active Expired
- 1972-08-24 ZA ZA725836A patent/ZA725836B/en unknown
- 1972-08-24 AT AT732372A patent/AT324321B/en not_active IP Right Cessation
- 1972-08-25 JP JP47085202A patent/JPS4832863A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
HU165059B (en) | 1974-06-28 |
FR2150828B1 (en) | 1976-04-16 |
DE2142563A1 (en) | 1973-05-03 |
AU4595072A (en) | 1974-02-28 |
BE788032A (en) | 1973-02-26 |
FR2150828A1 (en) | 1973-04-13 |
JPS4832863A (en) | 1973-05-02 |
GB1383408A (en) | 1974-02-12 |
NL7211327A (en) | 1973-02-27 |
AT324321B (en) | 1975-08-25 |
ZA725836B (en) | 1973-06-27 |
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