ES388067A1 - Process for isolating peptidase inhibitor - Google Patents

Process for isolating peptidase inhibitor

Info

Publication number
ES388067A1
ES388067A1 ES388067A ES388067A ES388067A1 ES 388067 A1 ES388067 A1 ES 388067A1 ES 388067 A ES388067 A ES 388067A ES 388067 A ES388067 A ES 388067A ES 388067 A1 ES388067 A1 ES 388067A1
Authority
ES
Spain
Prior art keywords
peptidase inhibitor
carbon atoms
reaction
starting material
hydrocarbon radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES388067A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Nutritional Products AG
Original Assignee
Pentapharm AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm AG filed Critical Pentapharm AG
Publication of ES388067A1 publication Critical patent/ES388067A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)

Abstract

A process for the preparation of a peptidase inhibitor preparation based on a starting material containing peptidase inhibitor, characterized in that the peptidase inhibitor contained in the starting material is transformed, by reaction with an acid ester of the orthophosphoric acid of the formula: ** (See formula) ** in which it represents a hydrocarbon radical with at least 2 carbon atoms, and R2 hydrogen or a hydrocarbon radical containing at least 2 carbon atoms, in a complex insoluble in water, but soluble in lower alkanols, a complex that by reaction with an inorganic base, mineral acid or alkaline earth metal salt soluble in a lower alkanol, breaks down to obtain the peptidase inhibitor. (Machine-translation by Google Translate, not legally binding)
ES388067A 1970-02-11 1971-02-08 Process for isolating peptidase inhibitor Expired ES388067A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH199670A CH539435A (en) 1970-02-11 1970-02-11 Process for obtaining a peptidase inhibitor

Publications (1)

Publication Number Publication Date
ES388067A1 true ES388067A1 (en) 1974-02-16

Family

ID=4223458

Family Applications (1)

Application Number Title Priority Date Filing Date
ES388067A Expired ES388067A1 (en) 1970-02-11 1971-02-08 Process for isolating peptidase inhibitor

Country Status (8)

Country Link
JP (1) JPS5020151B1 (en)
AT (1) AT307615B (en)
BR (1) BR7100950D0 (en)
CH (1) CH539435A (en)
DE (1) DE2103772C3 (en)
ES (1) ES388067A1 (en)
FR (1) FR2081503B1 (en)
GB (1) GB1337078A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63272020A (en) * 1987-04-30 1988-11-09 Harada Kogyo Kk Toroidal coil device and manufacture thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1155563B (en) * 1962-08-14 1963-10-10 Bayer Ag Process for the production of pure preparations of the kallikrein inactivator

Also Published As

Publication number Publication date
DE2103772A1 (en) 1971-08-26
GB1337078A (en) 1973-11-14
CH539435A (en) 1973-07-31
JPS5020151B1 (en) 1975-07-12
FR2081503B1 (en) 1974-11-15
FR2081503A1 (en) 1971-12-03
DE2103772C3 (en) 1975-03-13
BR7100950D0 (en) 1973-07-17
AT307615B (en) 1973-05-25
DE2103772B2 (en) 1974-07-18

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