ES365758A1 - Procedure for the obtaining of substitute gonanes. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of substitute gonanes. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES365758A1
ES365758A1 ES365758A ES365758A ES365758A1 ES 365758 A1 ES365758 A1 ES 365758A1 ES 365758 A ES365758 A ES 365758A ES 365758 A ES365758 A ES 365758A ES 365758 A1 ES365758 A1 ES 365758A1
Authority
ES
Spain
Prior art keywords
gonanes
translation
procedure
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES365758A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH383369A external-priority patent/CH503716A/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES365758A1 publication Critical patent/ES365758A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane

Abstract

Procedure for obtaining substituted gonanes, of formula Ic **(See formula)** wherein R2 represents an alkyl group containing from 1 to 3 carbon atoms, characterized in that it comprises cleaving a compound of formula II, **(See formula)** wherein R1 represents an alkyl group containing from 1 to 4 carbon atoms and preferably is methyl, and R2 has the meaning indicated above, by treating the compound of formula II with an acid under strong cleavage conditions. (Machine-translation by Google Translate, not legally binding)
ES365758A 1968-04-10 1969-04-08 Procedure for the obtaining of substitute gonanes. (Machine-translation by Google Translate, not legally binding) Expired ES365758A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72034268A 1968-04-10 1968-04-10
CH383369A CH503716A (en) 1968-04-10 1969-03-14 Process for the preparation of new 17B-Hydroxy-Gonans

Publications (1)

Publication Number Publication Date
ES365758A1 true ES365758A1 (en) 1971-04-01

Family

ID=25693954

Family Applications (1)

Application Number Title Priority Date Filing Date
ES365758A Expired ES365758A1 (en) 1968-04-10 1969-04-08 Procedure for the obtaining of substitute gonanes. (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
CH (1) CH507924A (en)
ES (1) ES365758A1 (en)

Also Published As

Publication number Publication date
CH507924A (en) 1971-05-31

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