ES385407A1 - Un procedimiento para la fabricacion de un polipeptido. - Google Patents
Un procedimiento para la fabricacion de un polipeptido.Info
- Publication number
- ES385407A1 ES385407A1 ES385407A ES385407A ES385407A1 ES 385407 A1 ES385407 A1 ES 385407A1 ES 385407 A ES385407 A ES 385407A ES 385407 A ES385407 A ES 385407A ES 385407 A1 ES385407 A1 ES 385407A1
- Authority
- ES
- Spain
- Prior art keywords
- lysyl
- valyl
- group
- protected
- prolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000001681 protective effect Effects 0.000 abstract 10
- 125000001424 substituent group Chemical group 0.000 abstract 10
- 239000002253 acid Substances 0.000 abstract 7
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 7
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 6
- -1 α-amino-isobutyryl Chemical group 0.000 abstract 6
- FUOOLUPWFVMBKG-UHFFFAOYSA-N 2-Aminoisobutyric acid Chemical compound CC(C)(N)C(O)=O FUOOLUPWFVMBKG-UHFFFAOYSA-N 0.000 abstract 4
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 4
- 150000001408 amides Chemical class 0.000 abstract 4
- 210000004899 c-terminal region Anatomy 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 abstract 4
- 235000019766 L-Lysine Nutrition 0.000 abstract 3
- 239000004472 Lysine Substances 0.000 abstract 3
- AWJGUZSYVIVZGP-YUMQZZPRSA-N Pro-Val Chemical compound CC(C)[C@@H](C(O)=O)NC(=O)[C@@H]1CCCN1 AWJGUZSYVIVZGP-YUMQZZPRSA-N 0.000 abstract 3
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 abstract 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 2
- 229930064664 L-arginine Natural products 0.000 abstract 2
- 235000014852 L-arginine Nutrition 0.000 abstract 2
- 108010077895 Sarcosine Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000004696 coordination complex Chemical class 0.000 abstract 2
- 229960002989 glutamic acid Drugs 0.000 abstract 2
- 229910001385 heavy metal Inorganic materials 0.000 abstract 2
- 229940043230 sarcosine Drugs 0.000 abstract 2
- 229960001153 serine Drugs 0.000 abstract 2
- 235000008733 Citrus aurantifolia Nutrition 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 229930195722 L-methionine Natural products 0.000 abstract 1
- 235000011941 Tilia x europaea Nutrition 0.000 abstract 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 1
- 239000004571 lime Substances 0.000 abstract 1
- 229960004452 methionine Drugs 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229960004441 tyrosine Drugs 0.000 abstract 1
- 229960004295 valine Drugs 0.000 abstract 1
- 239000004474 valine Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP44090321A JPS4826010B1 (enrdf_load_stackoverflow) | 1969-11-11 | 1969-11-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES385407A1 true ES385407A1 (es) | 1973-10-01 |
Family
ID=13995246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES385407A Expired ES385407A1 (es) | 1969-11-11 | 1970-11-10 | Un procedimiento para la fabricacion de un polipeptido. |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS4826010B1 (enrdf_load_stackoverflow) |
| CA (1) | CA951722A (enrdf_load_stackoverflow) |
| CH (1) | CH549556A (enrdf_load_stackoverflow) |
| DE (1) | DE2055141A1 (enrdf_load_stackoverflow) |
| ES (1) | ES385407A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2073339B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1292898A (enrdf_load_stackoverflow) |
| HU (1) | HU164986B (enrdf_load_stackoverflow) |
| NL (1) | NL7016460A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4298523A (en) * | 1980-06-17 | 1981-11-03 | Ortho Pharmaceutical Corporation | Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1493649A1 (de) * | 1963-08-16 | 1969-11-13 | Hoechst Ag | Verfahren zur Herstellung adrenocorticotrop wirksamer Peptide |
-
1969
- 1969-11-11 JP JP44090321A patent/JPS4826010B1/ja active Pending
-
1970
- 1970-11-10 HU HUTA1093A patent/HU164986B/hu unknown
- 1970-11-10 NL NL7016460A patent/NL7016460A/xx unknown
- 1970-11-10 ES ES385407A patent/ES385407A1/es not_active Expired
- 1970-11-10 DE DE19702055141 patent/DE2055141A1/de active Pending
- 1970-11-10 CA CA097,818,A patent/CA951722A/en not_active Expired
- 1970-11-10 FR FR7040468A patent/FR2073339B1/fr not_active Expired
- 1970-11-11 GB GB53573/70A patent/GB1292898A/en not_active Expired
- 1970-11-11 CH CH1668670A patent/CH549556A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2073339B1 (enrdf_load_stackoverflow) | 1975-06-06 |
| CA951722A (en) | 1974-07-23 |
| FR2073339A1 (enrdf_load_stackoverflow) | 1971-10-01 |
| DE2055141A1 (de) | 1971-05-19 |
| GB1292898A (en) | 1972-10-18 |
| NL7016460A (enrdf_load_stackoverflow) | 1971-05-13 |
| CH549556A (de) | 1974-05-31 |
| HU164986B (enrdf_load_stackoverflow) | 1974-05-28 |
| JPS4826010B1 (enrdf_load_stackoverflow) | 1973-08-03 |
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