ES385395A1 - Un metodo mejorado para la escision del grupo 7-carboxamidode una cefalosporina. - Google Patents
Un metodo mejorado para la escision del grupo 7-carboxamidode una cefalosporina.Info
- Publication number
- ES385395A1 ES385395A1 ES385395A ES385395A ES385395A1 ES 385395 A1 ES385395 A1 ES 385395A1 ES 385395 A ES385395 A ES 385395A ES 385395 A ES385395 A ES 385395A ES 385395 A1 ES385395 A1 ES 385395A1
- Authority
- ES
- Spain
- Prior art keywords
- sulfur
- oxygen
- integer
- formula
- see formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- HOKIDJSKDBPKTQ-UHFFFAOYSA-N 3-(acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C(NC(=O)CCCC(N)C(O)=O)C12 HOKIDJSKDBPKTQ-UHFFFAOYSA-N 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 5
- 229910052760 oxygen Inorganic materials 0.000 abstract 5
- 239000001301 oxygen Substances 0.000 abstract 5
- 229910052717 sulfur Inorganic materials 0.000 abstract 5
- 239000011593 sulfur Chemical group 0.000 abstract 5
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 229930186147 Cephalosporin Natural products 0.000 abstract 2
- -1 aminoadipoyl Chemical group 0.000 abstract 2
- 230000000903 blocking effect Effects 0.000 abstract 2
- 239000011203 carbon fibre reinforced carbon Chemical group 0.000 abstract 2
- 229940124587 cephalosporin Drugs 0.000 abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 1
- 125000004650 C1-C8 alkynyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 125000000262 haloalkenyl group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000000232 haloalkynyl group Chemical group 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87659769A | 1969-11-13 | 1969-11-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES385395A1 true ES385395A1 (es) | 1973-04-16 |
Family
ID=25368102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES385395A Expired ES385395A1 (es) | 1969-11-13 | 1970-11-10 | Un metodo mejorado para la escision del grupo 7-carboxamidode una cefalosporina. |
Country Status (24)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5248993B1 (enrdf_load_stackoverflow) * | 1971-07-29 | 1977-12-14 | ||
| US4008231A (en) * | 1975-09-15 | 1977-02-15 | Eli Lilly And Company | Preparation of 3-methoxymethylcephalosporins |
| GR70261B (enrdf_load_stackoverflow) * | 1977-12-12 | 1982-09-02 | Takeda Chemical Industries Ltd |
-
0
- BE BE758800D patent/BE758800A/xx not_active IP Right Cessation
-
1969
- 1969-12-12 BR BR215070/69A patent/BR6915070D0/pt unknown
-
1970
- 1970-10-20 ZA ZA707137A patent/ZA707137B/xx unknown
- 1970-10-25 IL IL35522A patent/IL35522A/xx unknown
- 1970-11-05 IE IE1411/70A patent/IE34699B1/xx unknown
- 1970-11-05 NL NLAANVRAGE7016199,A patent/NL171899C/xx not_active IP Right Cessation
- 1970-11-05 CY CY798A patent/CY798A/xx unknown
- 1970-11-05 GB GB5275570A patent/GB1302015A/en not_active Expired
- 1970-11-06 CA CA097,580A patent/CA977747A/en not_active Expired
- 1970-11-09 SU SU1490795A patent/SU501676A3/ru active
- 1970-11-10 SE SE7015136A patent/SE380808B/xx unknown
- 1970-11-10 ES ES385395A patent/ES385395A1/es not_active Expired
- 1970-11-10 CS CS7557A patent/CS167298B2/cs unknown
- 1970-11-11 NO NO4303/70A patent/NO143318C/no unknown
- 1970-11-11 YU YU2762/70A patent/YU36183B/xx unknown
- 1970-11-11 JP JP45099376A patent/JPS4940479B1/ja active Pending
- 1970-11-12 CH CH1675670A patent/CH550200A/xx not_active IP Right Cessation
- 1970-11-12 PL PL1970144387A patent/PL88926B1/pl unknown
- 1970-11-12 DE DE19702056491 patent/DE2056491A1/de active Pending
- 1970-11-13 RO RO64970A patent/RO58347A/ro unknown
- 1970-11-13 AT AT1025670A patent/AT301027B/de not_active IP Right Cessation
- 1970-11-13 FR FR707040881A patent/FR2067278B1/fr not_active Expired
-
1975
- 1975-12-30 MY MY99/75A patent/MY7500099A/xx unknown
-
1976
- 1976-03-25 HK HK175/76*UA patent/HK17576A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL171899C (nl) | 1983-06-01 |
| NL7016199A (enrdf_load_stackoverflow) | 1971-05-17 |
| SE380808B (sv) | 1975-11-17 |
| MY7500099A (en) | 1975-12-31 |
| CS167298B2 (enrdf_load_stackoverflow) | 1976-04-29 |
| NO143318B (no) | 1980-10-06 |
| SU501676A3 (ru) | 1976-01-30 |
| IE34699B1 (en) | 1975-07-23 |
| JPS4940479B1 (enrdf_load_stackoverflow) | 1974-11-02 |
| PL88926B1 (enrdf_load_stackoverflow) | 1976-10-30 |
| CY798A (en) | 1976-12-01 |
| IE34699L (en) | 1971-05-13 |
| YU36183B (en) | 1982-02-25 |
| RO58347A (enrdf_load_stackoverflow) | 1975-09-15 |
| YU276270A (en) | 1981-06-30 |
| CA977747A (en) | 1975-11-11 |
| FR2067278B1 (enrdf_load_stackoverflow) | 1973-02-02 |
| DE2056491A1 (de) | 1971-08-26 |
| AT301027B (de) | 1972-08-25 |
| ZA707137B (en) | 1972-05-31 |
| NL171899B (nl) | 1983-01-03 |
| FR2067278A1 (enrdf_load_stackoverflow) | 1971-08-20 |
| GB1302015A (enrdf_load_stackoverflow) | 1973-01-04 |
| HK17576A (en) | 1976-04-02 |
| IL35522A (en) | 1974-09-10 |
| NO143318C (no) | 1981-01-14 |
| BE758800A (fr) | 1971-05-12 |
| IL35522A0 (en) | 1970-12-24 |
| CH550200A (de) | 1974-06-14 |
| BR6915070D0 (pt) | 1973-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19930209 |