ES374515A1 - Procedure for obtaining new compounds with cardiovascular actions. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining new compounds with cardiovascular actions. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES374515A1
ES374515A1 ES374515A ES374515A ES374515A1 ES 374515 A1 ES374515 A1 ES 374515A1 ES 374515 A ES374515 A ES 374515A ES 374515 A ES374515 A ES 374515A ES 374515 A1 ES374515 A1 ES 374515A1
Authority
ES
Spain
Prior art keywords
translation
procedure
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES374515A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Liade SA
Original Assignee
Laboratorios Liade SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Liade SA filed Critical Laboratorios Liade SA
Priority to ES374515A priority Critical patent/ES374515A1/en
Priority to FR7044685A priority patent/FR2081346A1/en
Priority to DE19702061377 priority patent/DE2061377A1/en
Publication of ES374515A1 publication Critical patent/ES374515A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Procedure for obtaining synthesized compounds with cardiovascular actions, characterized by that aromatic amides of the type Ar-CONH2 where Ar can be heterocyclic, and sulfonic acid chlorides of the formula R - SO2Cl where R can be aryl or alkyl, and very particularly sulfonyl chlorides, are reacted, taking the piperazine amine as the molecular axis, until obtaining intermediate compounds of general formula **(See formula)** where R'= Ortho, Meta or Para Cl; 3, 4, 5-CH3O; For CH3C; Meta CF3; The reagents used are variable depending on the number of carbon atoms of the hydrocarbon chain - (CH2) n-o of the substituent of said chain, if any. (Machine-translation by Google Translate, not legally binding)
ES374515A 1969-12-12 1969-12-12 Procedure for obtaining new compounds with cardiovascular actions. (Machine-translation by Google Translate, not legally binding) Expired ES374515A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES374515A ES374515A1 (en) 1969-12-12 1969-12-12 Procedure for obtaining new compounds with cardiovascular actions. (Machine-translation by Google Translate, not legally binding)
FR7044685A FR2081346A1 (en) 1969-12-12 1970-12-11 1-benzamidoalkyl-4-camphorsulphonyl- - piperazines
DE19702061377 DE2061377A1 (en) 1969-12-12 1970-12-14 Process for the preparation of cardiovascular active compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES374515A ES374515A1 (en) 1969-12-12 1969-12-12 Procedure for obtaining new compounds with cardiovascular actions. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES374515A1 true ES374515A1 (en) 1972-01-01

Family

ID=8454556

Family Applications (1)

Application Number Title Priority Date Filing Date
ES374515A Expired ES374515A1 (en) 1969-12-12 1969-12-12 Procedure for obtaining new compounds with cardiovascular actions. (Machine-translation by Google Translate, not legally binding)

Country Status (3)

Country Link
DE (1) DE2061377A1 (en)
ES (1) ES374515A1 (en)
FR (1) FR2081346A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0533240A2 (en) * 1991-09-16 1993-03-24 Merck & Co. Inc. Substituted amine derivatives of piperazinylcamphorsulfonyl oxytocin antagonists
EP0533242A2 (en) * 1991-09-16 1993-03-24 Merck & Co. Inc. Substituted derivatives of piperazinylcamphorsulfonyl oxytocin antagonists

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES432334A1 (en) * 1974-11-27 1976-11-01 Liade Sa Lab 11 amidoarukiru 44 suruhoniruupiperajinkagobutsunoseizoho
US5648352A (en) * 1991-09-13 1997-07-15 Merck & Co., Inc. Piperazinylcamphorsulfonyl oxytocin antagonists
EP0533241A3 (en) * 1991-09-16 1993-09-29 Merck & Co. Inc. Substituted alkyl derivatives of piperazinylcamphorsulfonyl oxytocin antagonists
EP0708765A4 (en) * 1993-07-16 1996-06-26 Merck & Co Inc Substituted piperazinylcamphor derivatives as oxytocin antagonists
DE69430483D1 (en) * 1993-07-16 2002-05-29 Merck & Co Inc Benzoxazinone and benzopyrimidinone piperidinyl compounds as tocolytic oxytocin receptor antagonists
US5464788A (en) * 1994-03-24 1995-11-07 Merck & Co., Inc. Tocolytic oxytocin receptor antagonists

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0533240A2 (en) * 1991-09-16 1993-03-24 Merck & Co. Inc. Substituted amine derivatives of piperazinylcamphorsulfonyl oxytocin antagonists
EP0533242A2 (en) * 1991-09-16 1993-03-24 Merck & Co. Inc. Substituted derivatives of piperazinylcamphorsulfonyl oxytocin antagonists

Also Published As

Publication number Publication date
DE2061377A1 (en) 1971-06-16
FR2081346A1 (en) 1971-12-03
FR2081346B1 (en) 1974-06-21

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