ES373998A1 - Procedure for the production of orthosethyled feniletilaminas. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the production of orthosethyled feniletilaminas. (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Novartis AG
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JR Geigy AG
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Publication date
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Publication of ES373998A1publicationCriticalpatent/ES373998A1/en
Procedure for the production of ortho-substituted phenylethylanines corresponding to formula I-a **(See formula)** where R1 represents hydrogen, hydroxyl, chlorine or lower alkoxy or lower alkyl which comprise at most 4 carbon atoms, R'2 represents hydroxyl or methoxy and B represents alkyl, isoalkyl or cycloalkyl, each with 3 to 8 carbon atoms, inclusive, or the group -CR3R4R5, in which each of the symbols R3, R4 and R5 represent methyl or ethyl, and its acid addition salts, characterized by the reduction of a compound of formula II **(See formula)** where A represents the carbonyl group or the methylene group, B'has the meaning previously attributed to B, and may also represent alkanoyl or isoalkanoyl comprising 3 to 8 carbon atoms, inclusive, provided that only one of the symbols A and B'comprise a carbonyl group, and R1 and R2 have the same meaning as before, in an inert solvent, by means of a complex metal hydride or by means of borane or diborane; conversion, if desired, of a product in which R1 is lower alkoxy and/or R'2 is methoxy into the respective compound in which R1 and/or R'2 are hydroxyl, by cleavage of ether; and conversion of a product into an addition salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
ES373998A1968-11-291969-11-28Procedure for the production of orthosethyled feniletilaminas. (Machine-translation by Google Translate, not legally binding)
ExpiredES373998A1
(en)
Procedure for the preparation of 7-chlorine-1,2-dihydro-5-phenyl - 1,4-benzodiazepin-2-onas. (Machine-translation by Google Translate, not legally binding)