ES423376A1 - Bis-benzyl-acetic acid derivatives - Google Patents

Bis-benzyl-acetic acid derivatives

Info

Publication number
ES423376A1
ES423376A1 ES423376A ES423376A ES423376A1 ES 423376 A1 ES423376 A1 ES 423376A1 ES 423376 A ES423376 A ES 423376A ES 423376 A ES423376 A ES 423376A ES 423376 A1 ES423376 A1 ES 423376A1
Authority
ES
Spain
Prior art keywords
formula
different
same
symbols
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423376A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES423376A1 publication Critical patent/ES423376A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A process for the production of bis- (benzyl) acetic acid derivatives of formula I, **(See formula)** where the symbols R1, which may be the same or different, mean hydrogen, fluorine, chlorine, or straight chain alkoxy containing 1 to 4 carbon atoms, the symbols R2, which may be the same or different, mean methyl or ethyl, the symbols R3, which may be the same or different, signify methyl or ethyl, I (i) X signifies hydrogen and Y signifies -COOH, or (ii) X and Y are the same or different and each signifies a radical -COOR4, where R4 means alkyl of 1 to 4 carbon atoms, and salt forms of the compounds where X is hydrogen and Y is -COOH, characterized in that a compound of formula Ib is produced, **(See formula)** wherein R1, R2, R3 and R4 have the meanings indicated above, by reaction of a compound or compounds of formula III, where R1, R2 and R3 have the meanings indicated above, and X means chlorine or bromine, with a compound of formula IV, **(See formula)** where R4 has the meaning indicated above, and D stands for an alkali metal, in the presence of a strong base and in an inert organic solvent. (Machine-translation by Google Translate, not legally binding)
ES423376A 1973-02-20 1974-02-18 Bis-benzyl-acetic acid derivatives Expired ES423376A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33389273A 1973-02-20 1973-02-20
US40322573A 1973-10-03 1973-10-03

Publications (1)

Publication Number Publication Date
ES423376A1 true ES423376A1 (en) 1976-09-16

Family

ID=26988943

Family Applications (1)

Application Number Title Priority Date Filing Date
ES423376A Expired ES423376A1 (en) 1973-02-20 1974-02-18 Bis-benzyl-acetic acid derivatives

Country Status (16)

Country Link
JP (1) JPS5029534A (en)
AT (1) AT346308B (en)
CA (1) CA1043807A (en)
CH (1) CH591418A5 (en)
CS (1) CS170510B2 (en)
DD (1) DD110033A5 (en)
DE (1) DE2406881A1 (en)
ES (1) ES423376A1 (en)
FR (1) FR2218106B1 (en)
GB (2) GB1453643A (en)
HU (1) HU168102B (en)
IE (1) IE39419B1 (en)
IL (1) IL44224A (en)
NL (1) NL7402093A (en)
PH (1) PH10682A (en)
SE (1) SE399554B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607728A1 (en) * 1986-01-25 1987-07-30 Telefonbau & Normalzeit Gmbh TERMINAL OF A TELECOMMUNICATION SYSTEM

Also Published As

Publication number Publication date
GB1453644A (en) 1976-10-27
DD110033A5 (en) 1974-12-05
FR2218106B1 (en) 1978-01-13
PH10682A (en) 1977-08-10
FR2218106A1 (en) 1974-09-13
NL7402093A (en) 1974-08-22
GB1453643A (en) 1976-10-27
SE399554B (en) 1978-02-20
HU168102B (en) 1976-02-28
CS170510B2 (en) 1976-08-27
CA1043807A (en) 1978-12-05
IL44224A (en) 1977-11-30
IE39419L (en) 1974-08-20
DE2406881A1 (en) 1974-08-29
ATA125874A (en) 1978-03-15
AT346308B (en) 1978-11-10
AU6577274A (en) 1975-08-21
IE39419B1 (en) 1978-10-11
CH591418A5 (en) 1977-09-15
IL44224A0 (en) 1974-05-16
JPS5029534A (en) 1975-03-25

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