ES372227A1 - Un procedimiento para la preparacion de una nueva clase de derivados ergolinicos. - Google Patents
Un procedimiento para la preparacion de una nueva clase de derivados ergolinicos.Info
- Publication number
- ES372227A1 ES372227A1 ES372227A ES372227A ES372227A1 ES 372227 A1 ES372227 A1 ES 372227A1 ES 372227 A ES372227 A ES 372227A ES 372227 A ES372227 A ES 372227A ES 372227 A1 ES372227 A1 ES 372227A1
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- derivatives
- methoxy
- halogen
- ergolinic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- BPSNETAIJADFTO-UHFFFAOYSA-N 2-pyridinylacetic acid Chemical class OC(=O)CC1=CC=CC=N1 BPSNETAIJADFTO-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002908 adrenolytic effect Effects 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001805 chlorine compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000011987 methylation Effects 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- SIOXPEMLGUPBBT-UHFFFAOYSA-N picolinic acid Chemical compound OC(=O)C1=CC=CC=N1 SIOXPEMLGUPBBT-UHFFFAOYSA-N 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2217668 | 1968-10-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES372227A1 true ES372227A1 (es) | 1971-09-16 |
Family
ID=11192615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES372227A Expired ES372227A1 (es) | 1968-10-07 | 1969-10-06 | Un procedimiento para la preparacion de una nueva clase de derivados ergolinicos. |
Country Status (13)
-
1969
- 1969-09-26 NL NL6914648A patent/NL6914648A/xx unknown
- 1969-10-02 IE IE1370/69A patent/IE33331B1/xx unknown
- 1969-10-02 BR BR212978/69A patent/BR6912978D0/pt unknown
- 1969-10-02 GB GB1230515D patent/GB1230515A/en not_active Expired
- 1969-10-02 IL IL33107A patent/IL33107A/en unknown
- 1969-10-03 DK DK528269AA patent/DK124544B/da unknown
- 1969-10-03 AT AT933869A patent/AT290738B/de not_active IP Right Cessation
- 1969-10-03 DE DE19691950032 patent/DE1950032A1/de active Pending
- 1969-10-03 FR FR696933833A patent/FR2020031B1/fr not_active Expired
- 1969-10-03 BE BE739809D patent/BE739809A/xx unknown
- 1969-10-06 ES ES372227A patent/ES372227A1/es not_active Expired
- 1969-10-06 NO NO3976/69A patent/NO124775B/no unknown
- 1969-10-06 CH CH1501369A patent/CH518939A/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO124775B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-06-05 |
| IE33331B1 (en) | 1974-05-29 |
| GB1230515A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-05-05 |
| FR2020031B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-07-13 |
| NL6914648A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-04-09 |
| AT290738B (de) | 1971-06-11 |
| BE739809A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-04-03 |
| BR6912978D0 (pt) | 1973-05-24 |
| IL33107A0 (en) | 1969-12-31 |
| DE1950032A1 (de) | 1970-04-09 |
| CH518939A (de) | 1972-02-15 |
| IE33331L (en) | 1970-04-07 |
| FR2020031A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-07-10 |
| IL33107A (en) | 1973-02-28 |
| DK124544B (da) | 1972-10-30 |
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