ES366520A1 - Procedimiento para la preparacion de las nuevas alcanodioil-bis- (3-acilaminometil-5-carboxi - 2,4,6-triyodo - anilidas) apropiadas para la utilizacion en calidad de agentes de contraste de rayos x. - Google Patents
Procedimiento para la preparacion de las nuevas alcanodioil-bis- (3-acilaminometil-5-carboxi - 2,4,6-triyodo - anilidas) apropiadas para la utilizacion en calidad de agentes de contraste de rayos x.Info
- Publication number
- ES366520A1 ES366520A1 ES366520A ES366520A ES366520A1 ES 366520 A1 ES366520 A1 ES 366520A1 ES 366520 A ES366520 A ES 366520A ES 366520 A ES366520 A ES 366520A ES 366520 A1 ES366520 A1 ES 366520A1
- Authority
- ES
- Spain
- Prior art keywords
- alkylene
- novel compounds
- formula
- acid
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- -1 amine salts Chemical class 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 239000002872 contrast media Substances 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 150000003946 cyclohexylamines Chemical class 0.000 abstract 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/58—Preparation of carboxylic acid halides
- C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH662668A CH502104A (de) | 1968-05-02 | 1968-05-02 | Neue Röntgenkontrastmittel und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES366520A1 true ES366520A1 (es) | 1971-01-01 |
Family
ID=4312529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES366520A Expired ES366520A1 (es) | 1968-05-02 | 1969-04-26 | Procedimiento para la preparacion de las nuevas alcanodioil-bis- (3-acilaminometil-5-carboxi - 2,4,6-triyodo - anilidas) apropiadas para la utilizacion en calidad de agentes de contraste de rayos x. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3557197A (enExample) |
| AT (2) | AT285040B (enExample) |
| BE (1) | BE732412A (enExample) |
| BR (1) | BR6908500D0 (enExample) |
| CH (1) | CH502104A (enExample) |
| ES (1) | ES366520A1 (enExample) |
| FR (1) | FR2007675B1 (enExample) |
| GB (1) | GB1202179A (enExample) |
| NL (1) | NL6906750A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1491129A (en) * | 1975-06-04 | 1977-11-09 | Guerbet Sa | Iodo-benzene derivatives and an x-ray contrast medium containing them |
| DE2628517C2 (de) * | 1976-06-23 | 1985-02-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2853424A (en) * | 1952-08-06 | 1958-09-23 | Schering Ag | X-ray contrast agents comprising symmetrical bifunctional analogs of nu-acyl derivatives of 2, 4, 6 triiodo-3-amino benzoic acid |
| GB1033776A (en) * | 1963-06-06 | 1966-06-22 | Sterling Drug Inc | Iodinated acid amides and esters and salts thereof |
-
1968
- 1968-05-02 CH CH662668A patent/CH502104A/de not_active IP Right Cessation
-
1969
- 1969-04-01 GB GB07040/69A patent/GB1202179A/en not_active Expired
- 1969-04-07 US US814176A patent/US3557197A/en not_active Expired - Lifetime
- 1969-04-26 ES ES366520A patent/ES366520A1/es not_active Expired
- 1969-04-30 BE BE732412D patent/BE732412A/xx unknown
- 1969-04-30 AT AT412069A patent/AT285040B/de active
- 1969-04-30 AT AT1117369A patent/AT291229B/de not_active IP Right Cessation
- 1969-04-30 FR FR6913903A patent/FR2007675B1/fr not_active Expired
- 1969-05-02 NL NL6906750A patent/NL6906750A/xx unknown
- 1969-05-02 BR BR208500/69A patent/BR6908500D0/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR6908500D0 (pt) | 1973-01-04 |
| FR2007675A1 (enExample) | 1970-01-09 |
| FR2007675B1 (enExample) | 1974-03-22 |
| BE732412A (enExample) | 1969-10-30 |
| AT285040B (de) | 1970-10-12 |
| CH502104A (de) | 1971-01-31 |
| DE1922606A1 (de) | 1969-11-13 |
| NL6906750A (enExample) | 1969-11-04 |
| AT291229B (de) | 1971-07-12 |
| GB1202179A (en) | 1970-08-12 |
| DE1922606B2 (de) | 1977-03-17 |
| US3557197A (en) | 1971-01-19 |
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