ES357511A1 - Procedimiento para la preparacion de nuevos derivados de 5-nitro-2-furil-2-iso-xazolinas. - Google Patents
Procedimiento para la preparacion de nuevos derivados de 5-nitro-2-furil-2-iso-xazolinas.Info
- Publication number
- ES357511A1 ES357511A1 ES357511A ES357511A ES357511A1 ES 357511 A1 ES357511 A1 ES 357511A1 ES 357511 A ES357511 A ES 357511A ES 357511 A ES357511 A ES 357511A ES 357511 A1 ES357511 A1 ES 357511A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- substituted
- nhcoch
- nitro
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Nitrofuryl Chemical class 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- JLUWJHHWNWJLLJ-UHFFFAOYSA-N 5-nitrofuran-2-carbonitrile oxide Chemical compound [O-][N+]#CC1=CC=C([N+]([O-])=O)O1 JLUWJHHWNWJLLJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3935167 | 1967-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES357511A1 true ES357511A1 (es) | 1970-03-16 |
Family
ID=10409082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES357511A Expired ES357511A1 (es) | 1967-08-26 | 1968-08-23 | Procedimiento para la preparacion de nuevos derivados de 5-nitro-2-furil-2-iso-xazolinas. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3769295A (pm) |
| JP (1) | JPS4827310B1 (pm) |
| AT (1) | AT277221B (pm) |
| BE (1) | BE719891A (pm) |
| CA (1) | CA933926A (pm) |
| CH (1) | CH502372A (pm) |
| CS (1) | CS157037B2 (pm) |
| DE (1) | DE1795208A1 (pm) |
| DK (1) | DK118820B (pm) |
| ES (1) | ES357511A1 (pm) |
| FI (1) | FI48930C (pm) |
| FR (2) | FR1589115A (pm) |
| GB (1) | GB1234213A (pm) |
| IE (1) | IE32300B1 (pm) |
| NL (2) | NL6811722A (pm) |
| NO (1) | NO125931B (pm) |
| SE (1) | SE330540B (pm) |
| YU (1) | YU199068A (pm) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3915978A (en) * | 1970-01-07 | 1975-10-28 | Merck & Co Inc | Nitroimidazoles |
| US4010176A (en) * | 1972-10-27 | 1977-03-01 | Merck & Co., Inc. | Isoxazole substituted nitroimidazoles |
| US4203994A (en) * | 1976-06-14 | 1980-05-20 | Eli Lilly And Company | Fungicidal 3-phenyl-5-(substituted methyl)isoxazoles |
| US4109002A (en) * | 1976-06-14 | 1978-08-22 | Eli Lilly And Company | Fungicidal 3-phenyl-5-(substituted methyl) isoxaxoles |
| IL85691A0 (en) * | 1987-04-10 | 1988-08-31 | Pennwalt Corp | 5-(phenyl or phenoxymethyl)-3-(2-furanyl or 2-thienyl)-3-(1h-imidazol-1-ylmethyl)-2-methylisoxazolidines and salts thereof |
| PT920421E (pt) * | 1996-08-21 | 2003-03-31 | Upjohn Co | Derivados de isoxazolina uteis como agentes antimicrobianos |
| ATE222894T1 (de) * | 1998-02-13 | 2002-09-15 | Upjohn Co | Substituierte aminophenylisoxazolinderivate verwendbar als antimikrobielle agenzien |
| AU3180999A (en) * | 1998-02-25 | 1999-09-15 | Pharmacia & Upjohn Company | Substituted aminomethyl isoxazoline derivatives useful as antimicrobials |
| ES2256331T3 (es) | 2000-12-21 | 2006-07-16 | PHARMACIA & UPJOHN COMPANY LLC | Derivados de quinolina antimicrobianos y uso de los mismos para tratar infecciones bacterianas. |
| ATE323087T1 (de) * | 2001-10-25 | 2006-04-15 | Aryl substituierte oxazolidinone mit antibacterieller activität | |
| JP2005512975A (ja) * | 2001-10-25 | 2005-05-12 | アストラゼネカ アクチボラグ | 抗菌薬として有用なイソキサゾリン誘導体 |
| CN101774976B (zh) * | 2010-01-26 | 2012-05-09 | 天津药物研究院 | 磺酰基异噁唑啉衍生物及抗肿瘤用途 |
| CN101781294B (zh) * | 2010-03-10 | 2012-02-01 | 天津药物研究院 | 一类咪唑的衍生物、其制备方法和用途 |
| KR20180003534A (ko) * | 2015-02-27 | 2018-01-09 | 오피 바이오 팩토리 컴퍼니, 리미티드 | 카케로마이신 및 그의 유도체 제조방법 |
-
0
- NL NL137326D patent/NL137326C/xx active
-
1967
- 1967-08-26 GB GB3935167A patent/GB1234213A/en not_active Expired
-
1968
- 1968-08-09 FI FI682252A patent/FI48930C/fi active
- 1968-08-14 US US00752479A patent/US3769295A/en not_active Expired - Lifetime
- 1968-08-16 NL NL6811722A patent/NL6811722A/xx unknown
- 1968-08-16 NO NO3235/68A patent/NO125931B/no unknown
- 1968-08-16 DK DK397368AA patent/DK118820B/da unknown
- 1968-08-16 SE SE11046/68A patent/SE330540B/xx unknown
- 1968-08-22 CH CH1259968A patent/CH502372A/de not_active IP Right Cessation
- 1968-08-23 FR FR1589115D patent/FR1589115A/fr not_active Expired
- 1968-08-23 YU YU01990/68A patent/YU199068A/xx unknown
- 1968-08-23 ES ES357511A patent/ES357511A1/es not_active Expired
- 1968-08-23 CS CS605368A patent/CS157037B2/cs unknown
- 1968-08-23 CA CA028264A patent/CA933926A/en not_active Expired
- 1968-08-23 BE BE719891A patent/BE719891A/xx unknown
- 1968-08-23 AT AT824568A patent/AT277221B/de not_active IP Right Cessation
- 1968-08-23 JP JP43059998A patent/JPS4827310B1/ja active Pending
- 1968-08-23 DE DE19681795208 patent/DE1795208A1/de active Pending
- 1968-08-23 IE IE1030/68A patent/IE32300B1/xx unknown
- 1968-11-22 FR FR174905A patent/FR8102M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE719891A (pm) | 1969-02-24 |
| CS157037B2 (pm) | 1974-08-23 |
| AT277221B (de) | 1969-12-10 |
| SE330540B (pm) | 1970-11-23 |
| DK118820B (da) | 1970-10-12 |
| DE1795208A1 (de) | 1972-03-16 |
| GB1234213A (pm) | 1971-06-03 |
| NL6811722A (pm) | 1969-02-28 |
| IE32300B1 (en) | 1973-06-13 |
| NO125931B (pm) | 1972-11-27 |
| JPS4827310B1 (pm) | 1973-08-21 |
| CA933926A (en) | 1973-09-18 |
| FI48930B (pm) | 1974-10-31 |
| IE32300L (en) | 1969-02-26 |
| FR1589115A (pm) | 1970-03-23 |
| FI48930C (fi) | 1975-02-10 |
| US3769295A (en) | 1973-10-30 |
| NL137326C (pm) | |
| CH502372A (de) | 1971-01-31 |
| YU199068A (en) | 1978-05-15 |
| FR8102M (pm) | 1970-07-27 |
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